Results 11 to 20 of about 62,977 (257)
Reproductive Biology and Endocrinology, 2003 Retinoids, a class of compounds that include retinol and its metabolite, retinoic acid, are absolutely essential for ovarian steroid production, oocyte maturation, and early embryogenesis.
Malayer Jerry +2 more
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Meiosis occurs normally in the fetal ovary of mice lacking all retinoic acid receptors. [PDF]
Sci Adv, 2020 Gametes are generated through a specialized cell differentiation process, meiosis, which, in ovaries of most mammals, is initiated during fetal life. All-trans retinoic acid (ATRA) is considered as the molecular signal triggering meiosis initiation.
Vernet N +11 more
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Retinoic Acid Receptors in Acute Myeloid Leukemia Therapy. [PDF]
Cancers (Basel), 2019 Retinoic acid (RA) signaling pathways regulate fundamental biological processes, such as cell proliferation, development, differentiation, and apoptosis. Retinoid receptors (RARs and RXRs) are ligand-dependent transcription factors.
Martino OD, Welch JS.
europepmc +3 more sources
Nutrition & Metabolism, 2023 In the last century, vitamin A was identified that included the nutritional relevant vitamin A1 / provitamin A1, as well as the vitamin A2 pathway concept.
Torsten Bohn +4 more
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Neural Regeneration Research, 2019 All retinoids, which can be natural and synthetic, are chemically related to vitamin A. Both natural and synthetic retinoids use specific nuclear receptors such as retinoic acid receptors and retinoid X receptors to activate specific signaling pathways ...
Bhaskar C Das +2 more
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International Journal of Dermatology and Venerology, 2021 . Objective:. Acne inversa is a multifactorial chronic debilitating disease. Genetic factors are involved in 40% of patients, especially the nicastrin (NCSTN) gene.
Ying-Da Wu +8 more
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Journal of Lipid Research, 1992 In this study, we examined effects of retinol deficiency and three retinoids, all-trans-retinoic acid, 13-cis-retinoic acid, and etretin, the aromatic derivative of retinoic acid on nuclear retinoic acid receptor isoforms alpha, beta, and gamma mRNA in ...
Riaz-ul-Haq, F Chytil
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NADPH-cytochrome P450 reductase is regulated by all-trans retinoic acid and by 1,25-dihydroxyvitamin D3 in human acute myeloid leukemia cells. [PDF]
PLoS ONE, 2014 Acute myeloid leukemia (AML) cell lines can be driven to differentiate to monocyte-like cells by 1,25- dihydroxyvitamin D3 (1,25D) and to granulocyte-like cells by all-trans-retinoic acid (ATRA).
Elżbieta Gocek +3 more
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Thyroid hormone regulation of gene expression in primary cerebrocortical cells: role of thyroid hormone receptor subtypes and interactions with retinoic acid and glucocorticoids. [PDF]
PLoS ONE, 2014 The effects of thyroid hormone on brain development and function are largely mediated by the binding of 3,5,3'-triiodo-L-thyronine (T3) to its nuclear receptors (TR) to regulate positively or negatively gene expression.
Pilar Gil-Ibáñez +2 more
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Cloning retinoid and peroxisome proliferator-activated nuclear receptors of the Pacific oyster and in silico binding to environmental chemicals. [PDF]
PLoS ONE, 2017 Disruption of nuclear receptors, a transcription factor superfamily regulating gene expression in animals, is one proposed mechanism through which pollution causes effects in aquatic invertebrates.
Susanne Vogeler +3 more
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