Results 121 to 130 of about 121,956 (356)
Astrocyte Lipid Droplet Dynamics Orchestrate Neurological Disorders and Therapeutic Horizons
Small Science, EarlyView.This review examines astrocyte lipid droplet (LD) metabolism in neurological disorders, including Alzheimer's disease, stroke, epilepsy, and glioma. It analyzes regulatory mechanisms governing LD formation, transport, and degradation in astrocytes, highlighting their potential as biomarkers and therapeutic targets through integrative multiomics ...
Jiani Zhong +4 more
wiley +1 more source
Journal of Lipid Research, 1985 Chronic ethanol consumption reduces the liver retinoid store in man and rat. We have studied the effect of ethanol on some aspects of retinoid metabolism in parenchymal and nonparenchymal liver cells.
M Rasmussen +5 more
doaj
Frontiers in OncologyBackgroundRetinoid metabolism is critical for maintaining liver homeostasis, and its dysregulation is closely associated with liver diseases. Retinol binding protein 7 (RBP7) involves in retinoids transport, particularly in liver, indicating its ...
Jinhai Li +17 more
doaj +1 more source
A 66‐Year‐old Woman With Submammary Brownish Hyperkeratotic Plaques
JEADV Clinical Practice, EarlyView.
Antonia Kössinger +2 more
wiley +1 more source
VIEW, EarlyView.The mechanisms underlying neurodevelopmental toxicity induced by repeated exposure to general anesthesia in neonatal mice remain to be fully elucidated. In this study, neonatal mice were exposed to sevoflurane on postnatal days 6, 8, and 10. On postnatal day 30, the medial prefrontal cortex was collected for whole‐genome bisulfite sequencing and RNA ...
Yu Hou +10 more
wiley +1 more source
Targeted disruption of the mouse cis-retinol dehydrogenase gene: visual and nonvisual functions
Journal of Lipid Research, 2002 It has been proposed that cis-retinol dehydrogenase (cRDH) acts within the body to catalyze the oxidation of 9-cis-retinol, an oxidative step needed for 9-cis-retinoic acid synthesis, the oxidation of 11-cis-retinol [an oxidative step needed for 11-cis ...
Enyuan Shang +7 more
doaj
Journal of Lipid Research, 2021 : There is increasing recognition that dietary lipids can affect the expression of genes encoding their metabolizing enzymes, transporters, and binding proteins. This mechanism plays a pivotal role in controlling tissue homeostasis of these compounds and
Srinivasagan Ramkumar +3 more
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Australasian Journal of Dermatology, EarlyView.ABSTRACT Generalised Granuloma Annulare (GGA) is a chronic inflammatory skin disorder with no standard treatment. Since the last review in 2013, new treatments and varied responses have highlighted the need for an updated synthesis to guide clinical decisions.
Luca Bettolini +11 more
wiley +1 more source
Journal of Lipid Research, 1998 Keratinocytes differentiating in vitro exhibit greater cytosolic capacity for retinoic acid synthesis from retinol or retinaldehyde as compared to nondifferentiated cells (Siegenthaler et al. 1990. Biochem. J.
Dominique Chatellard-Gruaz +4 more
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ZSH‐2208: A novel retinoid with potent anti‐tumour effects on ESCC stem cells via RARγ–TNFAIP3 axis
Clinical and Translational MedicineBackgroud Oesophageal cancer ranks among the most prevalent malignant tumours globally, primarily consisting of oesophageal squamous cell carcinoma (ESCC).
Ruoxue Chen +7 more
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