Results 161 to 170 of about 155,897 (329)

Recent Developments in the Optical Control of Adrenergic Signaling

open access: yesMedicinal Research Reviews, Volume 45, Issue 5, Page 1307-1322, September 2025.
ABSTRACT Adrenoceptors (ARs) play a vital role in various physiological processes and are key therapeutic targets. The advent of optical control techniques, including optogenetics and photopharmacology, offers the potential to modulate AR signaling with precise temporal and spatial resolution. In this review, we summarize the latest advancements in the
Shuang Shi   +4 more
wiley   +1 more source

Distinct conformations of vitamin D receptor/retinoid X receptor-alpha heterodimers are specified by dinucleotide differences in the vitamin D-responsive elements of the osteocalcin and osteopontin genes. [PDF]

open access: bronze, 1996
Ada Staal   +10 more
openalex   +1 more source

Therapeutic Potential of Retinoid X Receptor Modulators for the Treatment of the Metabolic Syndrome

open access: yesPPAR Research, 2007
The increasing prevalence of obesity is a fundamental contributor to the growing prevalence of the metabolic syndrome. Rexinoids, a class of compounds that selectively bind and activate RXR, are being studied as a potential option for the treatment of ...
Jane A. Pinaire, Anne Reifel-Miller
doaj   +1 more source

Comparative Embryology and Transcriptomics of Asellus infernus, an Isopod Crustacean From Sulfidic Groundwater

open access: yesEvolution &Development, Volume 27, Issue 3, September 2025.
Individuals of Asellus infernus, a sulfidic subterranean population of the Asellus aquaticus species complex from southeastern Romania (left) and surface individuals of A. aquaticus (right). Extreme differences in phenotype are seen comparing the subterranean and surface individuals as adults (top panels) and as embryonic samples (bottom panels ...
Haeli J. Lomheim   +8 more
wiley   +1 more source

Induction of lysosomal phospholipase A2 through the retinoid X receptor in THP-1 cells

open access: yesJournal of Lipid Research, 2004
An acidic phospholipase A2 (LPLA2) was recently purified and cloned. THP-1 cells were used to characterize the gene induction of LPLA2. THP-1 cells were stimulated with several differentiation agents.
Akira Abe   +3 more
doaj  

The Vertebral Column of Flatfish: A Review

open access: yesReviews in Aquaculture, Volume 17, Issue 4, September 2025.
ABSTRACT Flatfish (Pleuronectiformes) encompass fascinating fish species known for their high gastronomical value, rearing performances, and market prices, which attract both economic and scientific interest. Despite these attributes, flatfish exhibit unique morphological, developmental, and biological features, as well as distinctive swimming ...
A. M. de Azevedo   +5 more
wiley   +1 more source

Myocardial Retinoid X Receptor, Thyroid Hormone Receptor, and Myosin Heavy Chain Gene Expression in the Rat During Adult Aging [PDF]

open access: bronze, 1999
Long Xu   +7 more
openalex   +1 more source

The Non‐Canonical ChREBPα Activity Suppresses the Activation of Hepatic Stellate Cells and Liver Fibrosis by Antagonizing TGF‐β‐E2F1 Axis

open access: yesAdvanced Science, Volume 12, Issue 29, August 7, 2025.
Intrahepatic microenvironment greatly impacts duration and degree of HSCs activation and development of liver fibrosis. By inhibiting TGFβ‐E2F1‐driven production of profibrogenic factors (CTGF and THBS1), hepatocyte ChREBPα monitors hepatic microenvironment and suppresses the overactivation of HSCs.
Jian Zhang   +10 more
wiley   +1 more source

Gene transcription of the retinoid X receptor α (RXRα) is regulated by fatty acids and hormones in rat hepatic cells [PDF]

open access: hybrid, 1998
Hilde Hermansen Steineger   +3 more
openalex   +1 more source

Home - About - Disclaimer - Privacy