Results 201 to 210 of about 155,897 (329)

Ligand-induced alteration of the protease sensitivity of retinoid X receptor alpha.

, 1994
Mark Leid
openalex   +1 more source

Heterodimeric Interaction between Retinoid X Receptor α and Orphan Nuclear Receptor OR1 Reveals Dimerization-Induced Activation as a Novel Mechanism of Nuclear Receptor Activation [PDF]

, 1997
Franziska F. Wiebel, Jan-Ακε Gustafsson   +1 more
openalex   +1 more source

Hydroxysteroid 17β‐dehydrogenase 13 (Hsd17b13) knockdown attenuates liver steatosis in high‐fat diet obese mice

Experimental Physiology, Volume 110, Issue 8, Page 1071-1086, 1 August 2025.
Abstract Hydroxysteroid 17β‐dehydrogenase 13 (HSD17B13) loss‐of‐function gene variants are associated with a decreased risk of metabolic dysfunction‐associated steatotic liver disease (MASLD). Our RNA‐seq analysis of steatotic liver from obese mice ± fenretinide treatment identified major beneficial effects of fenretinide on expression of hepatic genes
Shehroz Mahmood, Nicola Morrice, Dawn Thompson, Sara Milanizadeh, Sophie Wilson, Philip D. Whitfield, George D. Mcilroy, Justin J. Rochford, Nimesh Mody   +8 more
wiley   +1 more source

Inhibition of retinoid X receptor improved the morphology, localization of desmosomal proteins and paracellular permeability in three-dimensional cultures of mouse keratinocytes. [PDF]

Microscopy (Oxf), 2022
Ishikawa S, Nikaido M, Otani T, Ogata K, Iida H, Inai Y, Tamaoki S, Inai T.   +7 more
europepmc   +1 more source

Retinoid X Receptor Acts as a Hormone Receptor in Vivo to Induce a Key Metabolic Enzyme for 1,25-Dihydroxyvitamin D3 [PDF]

, 1995
Elizabeth A. Allegretto, Nirupama K. Shevde, Aihua Zou, Stanley R. Howell, Marcus F. Boehm, Bruce W. Hollis, J. Wesley Pike   +6 more
openalex   +1 more source

The human ABCG1 gene: identification of LXR response elements that modulate expression in macrophages and liver

Journal of Lipid Research, 2005
The ABC transporter ABCG1 (ATP binding cassette transporter G1), expressed in macrophages, liver, and other tissues, has been implicated in the efflux of cholesterol to high density lipoprotein.
Steven L. Sabol, H. Bryan Brewer, Jr., Silvia Santamarina-Fojo   +2 more
doaj  

An Isochroman Analog of CD3254 and Allyl-, Isochroman-Analogs of NEt-TMN Prove to Be More Potent Retinoid-X-Receptor (RXR) Selective Agonists Than Bexarotene. [PDF]

Int J Mol Sci, 2022
Jurutka PW, di Martino O, Reshi S, Mallick S, Sausedo MA, Moen GA, Lee IJ, Ivan DJ, Krall TD, Peoples SJ, Perez A, Tromba L, Le A, Khadka I, Petros R, Savage BM, Salama E, Salama J, Ziller JW, Noh Y, Lee MY, Liu W, Welch JS, Marshall PA, Wagner CE.   +24 more
europepmc   +1 more source

Identification of PLTP as an LXR target gene and apoE as an FXR target gene reveals overlapping targets for the two nuclear receptors

Journal of Lipid Research, 2002
Affymetrix microarray data and Northern blot assays demonstrated that phospholipid transfer protein (PL222222222216) was induced 6-fold when either murine or human macrophages were incubated in the presence of ligands for the liver X receptor (LXR) and ...
Puiying A. Mak, Heidi R. Kast-Woelbern, Andrew M. Anisfeld, Peter A. Edwards   +3 more
doaj  

Cooperative Formation of Higher Order Peroxisome Proliferator-activated Receptor and Retinoid X Receptor Complexes on the Peroxisome Proliferator Responsive Element of the Rat Hydratase-Dehydrogenase Gene [PDF]

, 1995
Ruiyin Chu, Yulian Lin, Mahendra S. Rao, Janardan K. Reddy   +3 more
openalex   +1 more source

Vitamin A is linked to the expression of the AI-CIII-AIV gene cluster in familial combined hyperlipidemia

Journal of Lipid Research, 1999
There is growing evidence of the capacity of vitamin A to regulate the expression of the genetic region that encodes apolipoproteins (apo) A-I, C-III, and A-IV.
Josep Ribalta, Josefa Girona, Joan C. Vallvé, Agnes E. La Ville, Mercedes Heras, Lluís Masana   +5 more
doaj