Results 211 to 220 of about 38,509 (256)
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Retinoids and photodamage

British Journal of Dermatology, 1992
Extensive well-controlled clinical studies performed over the past 5 years have demonstrated a consistent, dose-dependent, statistically significant improvement in the appearance of photodamaged skin after 3-6 months of daily treatment with topical 0.001-0.1% tretinoin cream.
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Retinoids and cancer

Cancer Chemotherapy and Pharmacology, 1979
The early and recent investigations in the field of retinoids and cancer are reviewed. The retinoids, including natural vitamin A compounds and their synthetic analogs, present a new class of substances exerting a prophylactic and a therapeutic effect both in certain experimental tumor models and in certain clinical conditions of preneoplastic and ...
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Retinoids and the Skin

Nutrition Reviews, 2009
Retinoids are a group of naturally occurring and synthetic compounds with vitamin A-like biological activity. They play an important role in vision, reproduction, growth, and epithelial cell differentiation. Recent discoveries of specific retinoid cellular binding proteins and nuclear receptors have led to a better (although not complete) understanding
T, Futoryan, B A, Gilchrest
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Retinoids and Ageing

Hormone Research, 2008
The observation that topical retinoic acid could attenuate wrinkles and other features of skin photoageing has projected this molecule into the media spotlight. Behind this effect are in fact major basic biological issues related to the role of retinoids in tissue maintenance and their possible interference with the molecular biology of cellular ageing.
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History of retinoids

Journal of the American Academy of Dermatology, 1982
The historical development of the chemistry and biology of vitamin A and its derivatives (retinoids) is briefly reviewed.
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Retinoid Specificity of Interphotoreceptor Retinoid-Binding Protein

Biochemistry, 1994
Interphotoreceptor retinoid-binding protein (IRBP), the predominant protein in the interphotoreceptor matrix of retina, has been implicated in transfer of retinoids between retinal pigment epithelium and photoreceptor cells. In this work, the interactions of several retinoids with IRBP were studied in order to clarify whether the protein displays ...
Y, Chen, N, Noy
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Chromatography of retinoids

Journal of Chromatography B: Biomedical Sciences and Applications, 1990
This article reviews the determination of retinoic acids and their metabolites (first-generation retinoids), aromatic retinoids (second generation) and arotinoids (third generation) in biological samples. Because of the sensitivity of the retinoids to isomerization and oxidation, special care has to be taken from sample collection and storage ...
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Retinoids in Chemoprevention

European Urology, 1999
Over several decades, in vitro experimental studies have demonstrated that retinoids effect the process of carcinogenesis and tend towards the alteration of cells back to more normal differentiation. This hypothesis has formed the basis of several chemopreventive studies in breast cancer, cervical cancer, head and neck cancer and lung cancer ...
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Retinoids: A review

Journal of the American Academy of Dermatology, 1984
The retinoids are synthetic derivatives of vitamin A. Isotretinoin (13-cis-retinoic acid) is now being widely used in the United States for severe acne and etretinate is available in Europe and other countries for psoriasis. These drugs are also effective for a number of other skin diseases.
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Retinoids and acne

Journal of the American Academy of Dermatology, 1988
Retinoids, chemicals that have vitamin A activity, have become important therapeutic agents for a variety of cutaneous disorders, including acne. This paper reviews the history of retinoid use in acne, including retinol, topical tretinoin, topical and systemic isotretinoin, systemic etretinate, and new investigational retinoid molecules.
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