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Retinoids

open access: yes, 2010
Sorg, Olivier   +3 more
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Retinoids

Current Opinion in Oncology, 1993
This review highlights recent advances in understanding the mode of action of retinoids at the level of molecular and cellular biology in relation to the new clinical results achieved with retinoids in various malignancies. All-trans-retinoic acid has been established in the clinic as a first-line differentiation therapy for acute promyelocytic ...
E E, Holdener, W, Bollag
openaire   +2 more sources

Retinoids and the Eye

Dermatologic Clinics, 1992
Systemic retinoids are being used more frequently to treat various disorders of the skin, particularly disorders of keratinization. They are promising agents for chemoprevention of cancer and as such may be widely used in the future. Both natural and synthetic retinoids may affect the eye, both on the surface epithelium and the visual metabolism. Three
E G, Gross, M A, Helfgott
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Retinoid Receptors

Dermatologic Clinics, 2007
"Retinoid" refers to the naturally occurring compounds with vitamin A activity and to synthetic analogues of retinol. Retinoids are key regulators of differentiation, proliferation, and inflammation. Their successful use in the treatment of various skin diseases and neoplasias has revolutionized the practice of dermatology as well as oncology.
Batya B, Davidovici   +2 more
openaire   +2 more sources

Retinoids in cosmeceuticals

Dermatologic Therapy, 2006
Retinoids are natural and synthetic vitamin A derivatives. They are lipophilic molecules and easily penetrate the epidermis. Their biologically active forms can modulate the expression of genes involved in cellular differentiation and proliferation. Retinoic acid (tretinoin), its 13-cis isomer isotretinoin, as well as various synthetic retinoids are ...
Olivier, Sorg   +3 more
openaire   +2 more sources

Retinoids and Contraception

Dermatology, 2009
The main side effect of the retinoids is teratogenicity. Every dermatologist has a moral obligation to ensure that this effect is avoided, and the present publication is aimed at helping prescribe these drugs. After a review of the key properties of each of the retinoids on the market, the different forms of contraception available and their indication
D L, Ceyrac, D, Serfaty, H, Lefrancq
openaire   +2 more sources

Alcohol and Retinoids

Alcoholism: Clinical and Experimental Research, 2001
This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in Yokohama, Japan. The chairs were Hirokazu Yokoyama and David Crabb. The presentations were (1) Roles of vitamin A, retinoic acid, and retinoid receptors in the expression of liver ALDH2, by J. Pinaire, R. Hasanadka, M. Fang, and David W.
D W, Crabb   +20 more
openaire   +2 more sources

Retinoids as Teratogens

Annual Review of Nutrition, 1995
Vitamin A is a necessary nutrient in the diet. However, excessive doses of retinoids by pregnant women result in teratogenesis. In this chapter, we initially discuss the occurrence and characteristics of fetal malformations associated with maternal ingestion of natural and synthetic retinoids in both experimental animals and humans.
D R, Soprano, K J, Soprano
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An overview of the retinoids

The American Journal of Medicine, 1989
The retinoids, a group of compounds consisting of vitamin A and its derivatives, have been the subject of intense investigation over the past 30 years. These molecules have shown beneficial effects in the areas of acne, psoriasis, neoplastic processes and, most recently, reversal of extrinsically aged skin.
openaire   +2 more sources

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