Results 201 to 210 of about 77,321 (327)

Review Article: Targeting Peroxisome Proliferator‐Activated Receptors in Primary Biliary Cholangitis

Alimentary Pharmacology &Therapeutics, Volume 63, Issue 9, Page 1215-1235, May 2026.
Peroxisome proliferator‐activated receptor (PPAR) agonists have emerged as important second‐line treatments in primary biliary cholangitis, with profiles influenced by different selectivity for α‐, δ‐ and γ‐isoforms. PPAR‐α and PPAR‐δ agonism improve cholestasis, with inflammation reduced via all isoforms. PPAR‐δ agonism also reduces pruritus.
Jörn M. Schattenberg, Jesus M. Banales, Gideon Hirschfield, Palak Trivedi, Edward E. Cable, Charles A. McWherter, Andrew N. Billin, Daria B. Crittenden, Grant Budas   +8 more
wiley   +1 more source

Targeting Multidrug Resistance in Cancer: Impact of Retinoids, Rexinoids, and Carotenoids on ABC Transporters. [PDF]

Int J Mol Sci
Čižmáriková M, Háziková V, Michalková R, Franko O, Lešková B, Homolya AD, Gabzdilová J, Takáč P.   +7 more
europepmc   +1 more source

Retinoids regulate stem cell differentiation

Journal of Cellular Physiology, 2011
L. Gudas, J. Wagner
semanticscholar   +1 more source

Acral Mesenchymal Spindle Cell Neoplasm With a Novel HMGA2::NCOA2 Fusion

Journal of Cutaneous Pathology, Volume 53, Issue 5, Page 402-406, May 2026.
ABSTRACT Molecular profiling has revolutionized the field of soft tissue pathology, enhancing diagnostic precision and treatment strategies. The integration of molecular analysis and immunohistochemistry has been crucial for classifying diagnostically challenging acral mesenchymal neoplasms.
Grace Z. Armstrong, Carina A. Dehner, Eitan Halper‐Stromberg, Esther Baranov, Anna C. Eden, Rachel P. Kowal   +5 more
wiley   +1 more source

Retinoic acid production via the ray-finned fish gene bco1l is essential for juvenile development. [PDF]

Genetics
Krupa LS, Villamayor PR, Bandara S, Zhang Y, Palmiotti A, von Lintig J, Bendesky A.   +6 more
europepmc   +1 more source

Macrophages Engulfing Apoptotic Cells Produce Nonclassical Retinoids To Enhance Their Phagocytic Capacity

Journal of Immunology, 2014
Z. Sarang, Gergely Joós, Éva Garabuczi, R. Rühl, C. Gregory, Z. Szondy   +5 more
semanticscholar   +1 more source

Structural bias in vitamin A metabolism: Why α-retinoids miss the eye. [PDF]

J Biol Chem
Bandara S, Saadane A, Ravichandran P, Ramkumar S, von Lintig J.   +4 more
europepmc   +1 more source

Preparation and Characterization of Zein/Salecan Nanocomposite Particles for Enhanced Stability and Bioactivity of Lipophilic Retinoids. [PDF]

Chem Asian J
Mei J, Li C, Li Y, Chang B, Jiang H, Yang C, Zhao B, Ngai T.   +7 more
europepmc   +1 more source

Dexamethasone‐Mediated Regulation of CYP3A4 and UGTs in Human Hepatoma HuH‐7 Cells

Fundamental &Clinical Pharmacology, Volume 40, Issue 3, May 2026.
ABSTRACT Background The application of human hepatic cell lines to early drug discovery and development instead of human primary hepatocytes (HPHs) has been limited because of the low level of drug‐metabolizing enzymes (DMEs). Objective The study aimed to evaluate the effects of dexamethasone (DEX) treatment on DME expression, activities, and ...
Hana Yu, Song Hee Lee, Ji Hyeon Kim, Seung Jin Kim, Hee Eun Kang   +4 more
wiley   +1 more source

Targeting CRABP1 Signalosomes in Managing Neurodegeneration. [PDF]

Biomolecules
Nhieu J, Wei LN.
europepmc   +1 more source