Results 31 to 40 of about 48,365 (197)

Regulating Retinoic Acid Availability during Development and Regeneration: The Role of the CYP26 Enzymes. [PDF]

open access: yes, 2020
This review focuses on the role of the Cytochrome p450 subfamily 26 (CYP26) retinoic acid (RA) degrading enzymes during development and regeneration. Cyp26 enzymes, along with retinoic acid synthesising enzymes, are absolutely required for RA homeostasis
Roberts, C
core   +4 more sources

Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis

open access: yesHepatology, EarlyView., 2022
Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog   +12 more
wiley   +1 more source

Biological Functions of RBP4 and Its Relevance for Human Diseases

open access: yesFrontiers in Physiology, 2021
Retinol binding protein 4 (RBP4) is a member of the lipocalin family and the major transport protein of the hydrophobic molecule retinol, also known as vitamin A, in the circulation.
Julia S. Steinhoff   +3 more
doaj   +1 more source

A Reliability Study in a Cohort of 207 Apparently Healthy Participants [PDF]

open access: yes, 2015
The reliability of single time point measurements of the novel adipokines retinol-binding protein 4 and omentin-1 in the blood has not been evaluated in large samples yet.
Aleksandrova, Krasimira   +10 more
core   +1 more source

Vitamin A Transport Mechanism of the Multitransmembrane Cell-Surface Receptor STRA6. [PDF]

open access: yes, 2015
Vitamin A has biological functions as diverse as sensing light for vision, regulating stem cell differentiation, maintaining epithelial integrity, promoting immune competency, regulating learning and memory, and acting as a key developmental morphogen ...
Kassai, Miki   +4 more
core   +2 more sources

Metabolic interactions between vitamin A and conjugated linoleic acid [PDF]

open access: yes, 2014
Lipid-soluble molecules share several aspects of their physiology due to their common adaptations to a hydrophilic environment, and may interact to regulate their action in a tissue-specific manner.
BANNI, SEBASTIANO   +7 more
core   +2 more sources

Vitamin A Status of Women and Children in Yaoundé and Douala, Cameroon, is Unchanged One Year after Initiation of a National Vitamin A Oil Fortification Program. [PDF]

open access: yes, 2017
Vitamin A (VA) fortification of cooking oil is considered a cost-effective strategy for increasing VA status, but few large-scale programs have been evaluated. We conducted representative surveys in Yaoundé and Douala, Cameroon, 2 years before and 1 year
Brown, Kenneth H   +7 more
core   +7 more sources

High resolution crystal structure data of human plasma retinol-binding protein (RBP4) bound to retinol and fatty acids

open access: yesData in Brief, 2018
Retinol is transported in vertebrate plasma bound to a protein called retinol-binding protein (RBP4) so far believed to be specific for the vitamin. When the protein is saturated with retinol it binds tightly to another plasma protein, transthyretin ...
Massimiliano Perduca   +4 more
doaj   +1 more source

Assessment of Serum Retinol Binding Protein 4 in Patients with Hepatocellular Carcinoma [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2018
Introduction: Retinol Binding Protein 4 (RBP4) may be indirectly involved in the induction of carcinogenesis as it was identified as a key regulator of insulin resistance in obesity and diabetes.
Yehia Mohamed El Shazly   +5 more
doaj   +1 more source

RPB4 and pathogenesis of diabetes [PDF]

open access: yes, 2007
Obesity is an important risk factor for a number of chronic diseases that impose a huge burden on individuals and society. Recently it has become clear that adipose tissue-secreted products may play a significant role in mediating many obesity-related ...
Kumar, Sudhesh   +1 more
core   +1 more source

Home - About - Disclaimer - Privacy