Results 51 to 60 of about 14,990 (203)
The Method of Viral Mimicry in Oncology and Prospects for its Improvement
Архивъ внутренней медицины, 2023 Malignant neoplasms cells are characterized by clonal evolution that is resistant to the applied antitumor drug and evasion from the effects of the immune system.
R. N. Mustafin
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LTR retrotransposon dynamics in the evolution of the olive (Olea europaea) genome. [PDF]
, 2014 Improved knowledge of genome composition, especially of its repetitive component, generates important information for both theoretical and applied research.
A. Cavallini +36 more
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Heterogeneity in Ty1-copia group of retroelements in chickpea (Cicer arietinum) genome [PDF]
, 2007 Retrotransposons constitute a major fraction of plant genomes and these elements may have played a significant role in evolution and sequence organization of genomes.
Kailash C. Upadhyaya, Manoj K. Rajput
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Giant reverse transcriptase-encoding transposable elements at telomeres [PDF]
, 2017 Author Posting. © The Author(s), 2017. This is the author's version of the work. It is posted here by permission of Oxford University Press for personal use, not for redistribution.
Arkhipova, Irina R. +2 more
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An autoimmune disease prevented by anti-retroviral drugs
Retrovirology, 2011 Background Both Aicardi-Goutières syndrome, a Mendelian mimic of congenital infection, and the autoimmune disease systemic lupus erythematosus can result from mutations in the gene encoding the enzyme Trex1.
Beck-Engeser Gabriele B +2 more
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eLife, 2022 DNA methylation, repressive histone modifications, and PIWI-interacting RNAs are essential for controlling retroelement silencing in mammalian germ lines. Dysregulation of retroelement silencing is associated with male sterility.
Kei Fukuda +6 more
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CARE1, a TY3-gypsy long terminal repeat retrotransposon in the food legume chickpea (Cicer arietinum L) [PDF]
, 2007 We report a novel Ty3-gypsy long terminal repeat retrotransposon CARE1 (_Cicer arietinum_ retro-element 1) in chickpea. This 5920-bp AT-rich (63%) element carries 723-bp 5' and 897-bp 3' LTRs respectively flanking an internal region of 4300-bp.
Kailash C. Upadhyaya, Manoj D. R. Rajput
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, 2002 The eukaryotic genome has undergone a series of epidemics of amplification of mobile elements that have resulted in most eukaryotic genomes containing much more of this \u27junk\u27 DNA than actual coding DNA.
Batzer, Mark A., Deininger, Prescott L.
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Retrovirology, 2012 Background The identification of cellular factors that regulate the replication of exogenous viruses and endogenous mobile elements provides fundamental understanding of host-pathogen relationships.
Arjan-Odedra Shetal +4 more
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A frequent SNP in TRIM5α strongly enhances the innate immune response against LINE-1 elements
Frontiers in Immunology, 2023 The intracellular restriction factor TRIM5α inhibits endogenous LINE-1 retroelements. It induces innate immune signaling cascades upon sensing of cytoplasmic LINE-1 complexes, thereby underlining its importance for protecting the human genome from ...
Justine Lagisquet +6 more
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