Results 91 to 100 of about 995,941 (287)
Advanced Science, EarlyView.In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang +11 more
wiley +1 more source
Retrograde signaling: Organelles go networking
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2016 The term retrograde signaling refers to the fact that chloroplasts and mitochondria utilize specific signaling molecules to convey information on their developmental and physiological states to the nucleus and modulate the expression of nuclear genes accordingly.
Kleine, Tatjana, Leister, Dario Michael
openaire +3 more sources
A role for nitric oxide-driven retrograde signaling in the consolidation of a fear memory
Frontiers in Behavioral Neuroscience, 2010 In both invertebrate and vertebrate models of synaptic plasticity, signaling via the putative “retrograde messenger” nitric oxide (NO) has been hypothesized to serve as a critical link between functional and structural alterations at pre- and
Kathie A Overeem +6 more
doaj +1 more source
Mitochondria-To-Nucleus Retrograde Signaling And Its Role In Cancer [PDF]
, 2018 Mitochondrial dysfunction is considered a hallmark of cancer. Mitochondria are essential, cellular organelles that participate in processes including energy production, calcium homeostasis and steroid metabolism.
Carden, Trevor
core
, 2013 Blockage of retrograde axon transport in the retinocollicular pathway with lidocaine causes rapid, reversible decrease of PERG amplitude and increase in PERG latency, implying that intact retrograde signaling is necessary for the normal electrical ...
Porciatti, Vittorio +3 more
core +1 more source
, 2023 Retrograde signaling modulates the expression of nuclear genome-encoded organelle proteins to adjust organelle function in response to environmental cues.
Zhenyu Gao (830064) +4 more
core +1 more source
Advanced Science, EarlyView.As a novel adipose‐derived neurotrophic factor, Follistatin‐like 1 is endocytosed by sympathetic neurons primarily via tropomyosin‐related kinase B. This process promotes sympathetic innervation in adipose tissue and norepinephrine release, leading to white adipose tissue browning, enhanced thermogenesis, and anti‐obesity effects in mice.
Xiao‐Wei Jia +13 more
wiley +1 more source
Frontiers in Plant Science, 2015 Carotenoids (C40) are synthesized in plastids and perform numerous important functions in these organelles. In addition, carotenoids can be processed into smaller signaling molecules that regulate various phases of the plant’s life cycle.
Li eTian
doaj +1 more source
, 2023 Retrograde signaling modulates the expression of nuclear genome-encoded organelle proteins to adjust organelle function in response to environmental cues.
Zhenyu Gao (830064) +4 more
core +1 more source
Advanced Science, EarlyView.Microgels enable independent control of stiffness and interstitial space, overcoming limitations of conventional 3D hydrogels. Using fragmented gelatin methacryloyl microgels, we show that stiffness does not restrict non‐metastatic breast cancer growth, contrary to bulk hydrogels, and reveal the role of adherent‐to‐suspension transition in cancer ...
Danielle Vahala +15 more
wiley +1 more source