Results 71 to 80 of about 995,941 (287)

Gonadotropin‐Inhibitory Hormone (GnIH) and Its Receptor GPR147 Mediates Acute Stress‐Induced Activation of the Locus Coeruleus‐SAM Axis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Gonadotropin‐inhibitory hormone (GnIH, also known as RFamide‐related peptide‐3, RFRP‐3) is a hypothalamic neuropeptide that regulates vertebrate reproduction via its receptor GPR147. Although GnIH is known to mediate stress‐induced reproductive suppression, its role in broader stress responses remains unclear.
Jiani Zhang   +18 more
wiley   +1 more source

Communication Between Mitochondria and Nucleus With Retrograde Signals

open access: yesShengwu huaxue yu shengwu wuli jinzhan
Mitochondria, the primary energy-producing organelles of the cell, also serve as signaling hubs and participate in diverse physiological and pathological processes, including apoptosis, inflammation, oxidative stress, neurodegeneration, and tumorigenesis.
ZHANG Wen-Long, QUAN Lei, ZHAO Yun-Gang
doaj   +1 more source

Chloroplast retrograde regulation of heat stress responses in plants

open access: yesFrontiers in Plant Science, 2016
It is well known that intracellular signaling from chloroplast to nucleus plays a vital role in stress responses to survive environmental perturbations.
Ai-Zhen eSun, Fang-Qing eGuo
doaj   +1 more source

Integrating Genetics With Epidemiological Measurements Identifies Burden QTLs of Inflammatory Bowel Disease across 20 Countries

open access: yesAdvanced Science, EarlyView.
The burden quantitative trait locus (bQTL) analysis integrates epidemiological data from GBD study with genotype of 2 621 978 SNPs from 2414 individuals in 1000 Genomes Project across 20 countries. rs7633471 shows the strongest effect that each increase in centi‐allele frequency of the allele C associated with 10.00 decrease of age‐standardized ...
Chen Sun   +27 more
wiley   +1 more source

The Yeast Retrograde Response as a Model of Intracellular Signaling of Mitochondrial Dysfunction

open access: yesFrontiers in Physiology, 2012
Mitochondrial dysfunction activates intracellular signaling pathways that impact yeast longevity, and the best known of these pathways is the retrograde response.
S. Michal eJazwinski, Andres eKriete
doaj   +1 more source

Chloroplast-localized GUN1 contributes to the acquisition of basal thermotolerance in Arabidopsis thaliana

open access: yesFrontiers in Plant Science, 2022
Heat stress (HS) severely affects different cellular compartments operating in metabolic processes and represents a critical threat to plant growth and yield.
Cecilia Lasorella   +7 more
doaj   +1 more source

Table_11_MORF2-mediated plastidial retrograde signaling is involved in stress response and skotomorphogenesis beyond RNA editing.xlsx

open access: yes, 2023
Retrograde signaling modulates the expression of nuclear genome-encoded organelle proteins to adjust organelle function in response to environmental cues.
Zhenyu Gao (830064)   +4 more
core   +1 more source

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

open access: yesAdvanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo   +14 more
wiley   +1 more source

Image_5_MORF2-mediated plastidial retrograde signaling is involved in stress response and skotomorphogenesis beyond RNA editing.tif

open access: yes, 2023
Retrograde signaling modulates the expression of nuclear genome-encoded organelle proteins to adjust organelle function in response to environmental cues.
Zhenyu Gao (830064)   +4 more
core   +1 more source

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