Results 111 to 120 of about 995,941 (287)
Retrograde signaling modulates the expression of nuclear genome-encoded organelle proteins to adjust organelle function in response to environmental cues.
Zhenyu Gao (830064) +4 more
core +1 more source
In this study, we demonstrate that Zdhhc17, acting as a PAT, suppresses neuronal apoptosis and promotes axon regeneration after injury, thereby enhancing functional recovery following SCI. In this context, Kpna2 and Ipo9 serve as novel palmitoylation substrates of Zdhhc17, whose palmitoylation prevents the injury‐induced degradation of their proteins ...
Meixuan Chen +12 more
wiley +1 more source
Contextual cues recruit the glutamatergic vCA1–dmPFC pathway to retrieve morphine reward memory by reshaping cell‐type‐specific prefrontal microcircuit activity. Distinct regulation of PV+ and SST+ interneurons defines this hippocampal–prefrontal mechanism.
Zhifeng Shi +8 more
wiley +1 more source
Reconsidering the nature and mode of action of metabolite retrograde signals from the chloroplast
Plant organelles produce retrograde signals to alter nuclear gene expression in order to coordinate their biogenesis, maintain homeostasis or optimize their performance under adverse conditions.
Gonzalo Martín Estavillo +3 more
doaj +1 more source
SAV1 in Cooperation With FKBP52 Participates in Implantation
The MST‐SAV1 complex modulates FKBP52 phosphorylation to fine‐tune PR activity, ensuring timely uterine transition to receptivity under estrogen signaling for implantation. Stromal SAV1 scaffolds MST1/2‐mediated FKBP52 phosphorylation via noncanonical Hippo to promote PR activity.
Yuhan Shao +10 more
wiley +1 more source
Retrograde signaling modulates the expression of nuclear genome-encoded organelle proteins to adjust organelle function in response to environmental cues.
Zhenyu Gao (830064) +4 more
core +1 more source
In this work, we present a bile‐based memristor hardware framework that enables direct, label‐free identification of cholelithiasis and gallbladder cancer at the device level. The Ag/bile/FTO memristor features stable resistive switching and disease‐specific electrical responses, providing a conceptual foundation for circuits and an integrated ERCP ...
Junming Zhu +17 more
wiley +1 more source
GUN1, a jack-of-all-trades in chloroplast protein homeostasis and signaling
The GUN1 (GENOMES UNCOUPLED 1) gene has been reported to encode a chloroplast-localized pentatricopeptide-repeat protein, which acts to integrate multiple indicators of plastid developmental stage and altered plastid function, as part of chloroplast-to ...
Monica Colombo +4 more
doaj +1 more source
Retrograde signaling modulates the expression of nuclear genome-encoded organelle proteins to adjust organelle function in response to environmental cues.
Zhenyu Gao (830064) +4 more
core +1 more source
A Molecularly Defined Midbrain Circuit Mechanism for Sound‐Driven Defensive Behavior and Anxiety
Schematic diagram showing the Cbln2+ ICx–dPAG circuit for sound‐driven defensive and anxiety‐like behaviors. ABSTRACT The innate defense behaviors in response to threatening sounds play a fundamental role in survival. However, the neural circuits that detect threat‐relevant auditory cues and transform them into defensive behaviors remain poorly defined.
Jie Cao +8 more
wiley +1 more source

