Results 101 to 110 of about 995,941 (287)
Mitochondrial emitted electromagnetic signals mediate retrograde signaling
Medical Hypotheses, 2015 Recent evidence shows that mitochondria regulate nuclear transcriptional activity both in normal and cell stress conditions, known as retrograde signaling. Under normal mitochondrial function, retrograde signaling is associated with mitochondrial biogenesis, normal cell phenotype and metabolic profile.
Bagkos, Georgios +2 more
openaire +3 more sources
Spatial‐specific functions in retrograde neuronal signalling [PDF]
Traffic, 2017 Neurons are highly polarized cells, possessing long axons that can extend to more than 1‐m long in adult humans. In order to survive and maintain proper functions, neurons have to respond accurately in both space and time to intracellular or intercellular cues.
Zahavi EE, Maimon R, Perlson E.
openaire +2 more sources
, 2023 Retrograde signaling modulates the expression of nuclear genome-encoded organelle proteins to adjust organelle function in response to environmental cues.
Zhenyu Gao (830064) +4 more
core +1 more source
Advanced Science, EarlyView.Boronic acid‐based fluorescent hybrids have been used as part of a versatile platform for real‐time metabolic bioimaging across cellular and organismal scales. Including glucose‐responsive imaging in living cells and in an insulin‐deficient vertebrate model, this work opens new opportunities for the development of precision diagnostics, metabolic ...
Haobo Ge +13 more
wiley +1 more source
Neurobiology of Stress, 2019 Glucocorticoids induce a rapid synthesis of endocannabinoid in hypothalamic neuroendocrine cells by activation of a putative membrane receptor. Somato-dendritically released endocannabinoid acts as a retrograde messenger to suppress excitatory synaptic ...
Christina Harris +3 more
doaj +1 more source
, 2023 Retrograde signaling modulates the expression of nuclear genome-encoded organelle proteins to adjust organelle function in response to environmental cues.
Zhenyu Gao (830064) +4 more
core +1 more source
Advanced Science, EarlyView.A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung +15 more
wiley +1 more source
, 2023 Retrograde signaling modulates the expression of nuclear genome-encoded organelle proteins to adjust organelle function in response to environmental cues.
Zhenyu Gao (830064) +4 more
core +1 more source
Abstract Representation of Movement Parameters in Basal Ganglia Output
Advanced Science, EarlyView.The basal ganglia output provides a scalable velocity/position signal across behavioral contexts, supporting the idea that these variables are represented in the brain as abstract entities rather than as fixed changes in joint angles or specific sets of body effectors.
Ana Silvia Báez‐Cordero +3 more
wiley +1 more source
eLife, 2015 The role of the primary cilium in key signaling pathways depends on dynamic regulation of ciliary membrane protein composition, yet we know little about the motors or membrane events that regulate ciliary membrane protein trafficking in existing ...
Muqing Cao +7 more
doaj +1 more source