Results 31 to 40 of about 67,814 (281)
Retrotransposon hypomethylation in melanoma and expression of a placenta-specific gene.
PLoS ONE, 2014 In the human placenta, DNA hypomethylation permits the expression of retrotransposon-derived genes that are normally silenced by methylation in somatic tissues.
Erin C Macaulay +5 more
doaj +1 more source
Diseases of the nERVous system: retrotransposon activity in neurodegenerative disease
Mobile DNA, 2019 Transposable Elements (TEs) are mobile genetic elements whose sequences constitute nearly half of the human genome. Each TE copy can be present in hundreds to thousands of locations within the genome, complicating the genetic and genomic studies of these
O. Tam, L. Ostrow, Molly Gale Hammell
semanticscholar +1 more source
R-loop landscape in mature human sperm: Regulatory and evolutionary implications
Frontiers in Genetics, 2023 R-loops are three-stranded nucleic acid structures consisting of an RNA:DNA hybrid and a displaced DNA strand. While R-loops pose a potential threat to genome integrity, they constitute 5% of the human genome.
Maurice Scheuren +2 more
doaj +1 more source
Mouse germ line mutations due to retrotransposon insertions
Mobile DNA, 2019 Transposable element (TE) insertions are responsible for a significant fraction of spontaneous germ line mutations reported in inbred mouse strains. This major contribution of TEs to the mutational landscape in mouse contrasts with the situation in human,
L. Gagnier, V. Belancio, D. Mager
semanticscholar +1 more source
The 5' untranslated region of the I factor, a long interspersed nuclear element-like retrotransposon of Drosophila melanogaster, contains an internal promoter and sequences that regulate expression [PDF]
, 1993 The I-R system of hybrid dysgenesis in Drosophila melanogaster is controlled by a long interspersed nuclear element-like retroposon, the I factor.
BUCHETON, A +3 more
core +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2017 Significance The genetic basis of X-Linked dystonia-parkinsonism (XDP) has been difficult to unravel, in part because all patients inherit the same haplotype of seven sequence variants, none of which has ever been identified in control individuals.
D. Bragg +20 more
semanticscholar +1 more source
Short-term mutagenicity test by using IRAP molecular marker in rice grown under herbicide treatment
Biotechnology & Biotechnological Equipment, 2018 Rice is an economically important plant as well as a model organism. The rice genome consists of 35% retrotransposons. Although most of the retrotransposons are inactivated through evolutionary processes, they can be activated under various biotic and ...
Sibel Yilmaz +3 more
doaj +1 more source
Frontiers in Plant Science, 2018 Sugarcane (Saccharum spp. hybrids) is an economically important crop widely grown in tropical and subtropical regions for sugar and ethanol production.
Anupma Sharma +11 more
doaj +1 more source
Structure of the Ty3/Gypsy retrotransposon capsid and the evolution of retroviruses
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance Long-terminal repeat (LTR) retrotransposon sequences are widespread in eukaryotic genomes. They have been adapted to perform functions ranging from placental development to antiviral defense.
S. Dodonova +4 more
semanticscholar +1 more source
Frontiers in Neurology, 2023 BackgroundSINE-VNTR-Alu (SVA) retrotransposons are hominid-specific elements which have been shown to play important roles in processes such as chromatin structure remodelling and regulation of gene expression demonstrating that these repetitive elements
Alexander Fröhlich +9 more
doaj +1 more source