Results 41 to 50 of about 50,973 (340)

Diseases of the nERVous system: retrotransposon activity in neurodegenerative disease

open access: yesMobile DNA, 2019
Transposable Elements (TEs) are mobile genetic elements whose sequences constitute nearly half of the human genome. Each TE copy can be present in hundreds to thousands of locations within the genome, complicating the genetic and genomic studies of these
O. Tam, L. Ostrow, Molly Gale Hammell
semanticscholar   +1 more source

Retrotransposons in pluripotent stem cells [PDF]

open access: yesCell Regeneration, 2020
AbstractTransposable elements constitute about half of the mammalian genome, and can be divided into two classes: the class I (retrotransposons) and the class II (DNA transposons). A few hundred types of retrotransposons, which are dynamic and stage specific, have been annotated.
Junjiu Huang   +3 more
openaire   +4 more sources

Structure of the Ty3/Gypsy retrotransposon capsid and the evolution of retroviruses

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance Long-terminal repeat (LTR) retrotransposon sequences are widespread in eukaryotic genomes. They have been adapted to perform functions ranging from placental development to antiviral defense.
S. Dodonova   +4 more
semanticscholar   +1 more source

The DIRS1 Group of Retrotransposons [PDF]

open access: yesMolecular Biology and Evolution, 2001
Only three retrotransposons of the DIRS1 group have previously been described: DIRS1 from the slime mold Dictyostelium discoideum, PAT from the nematode Panagrellus redivivus, and Prt1 from the zygomycetous fungus Phycomyces blakesleeanus. Analyses of the reverse transcriptase sequences encoded by these elements suggest that they are related to the ...
Russell T. M. Poulter   +1 more
openaire   +3 more sources

COMPARATIVE RETROTRANSPOSON ANALYSIS in WHEAT

open access: yesJournal of Advanced Research in Natural and Applied Sciences, 2021
The presence of retrotransposons is associated with polyploidy, especially in wheat, and may cause an increase in genome size. In this study, the evolutionary information was aimed to reveal based on the comparison retrotrans-poson movements between bread and einkorn wheat Siyez.
Seray Altıntaş   +2 more
openaire   +5 more sources

Molecular characterization reveals no functional evidence for naturally occurring cross‐kingdom RNA interference in the early stages of Botrytis cinerea–tomato interaction

open access: yesMolecular Plant Pathology, Volume 24, Issue 1, Page 3-15, January 2023., 2023
Botrytis cinerea mutants lacking both Dicer‐like genes displayed a >99% reduction of transposable element‐derived small RNA (sRNA) production, but were not reduced in virulence, indicating redundancy of sRNAs in fungal virulence. Abstract Plant immune responses are triggered during the interaction with pathogens.
Si Qin   +11 more
wiley   +1 more source

Comparative Analysis of Homologous Sequences of Saccharum officinarum and Saccharum spontaneum Reveals Independent Polyploidization Events

open access: yesFrontiers in Plant Science, 2018
Sugarcane (Saccharum spp. hybrids) is an economically important crop widely grown in tropical and subtropical regions for sugar and ethanol production.
Anupma Sharma   +11 more
doaj   +1 more source

Disease onset in X-linked dystonia-parkinsonism correlates with expansion of a hexameric repeat within an SVA retrotransposon in TAF1

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2017
Significance The genetic basis of X-Linked dystonia-parkinsonism (XDP) has been difficult to unravel, in part because all patients inherit the same haplotype of seven sequence variants, none of which has ever been identified in control individuals.
D. Bragg   +20 more
semanticscholar   +1 more source

RNA Editing and Retrotransposons in Neurology [PDF]

open access: yesFrontiers in Molecular Neuroscience, 2018
Compared to sites in protein-coding sequences many more targets undergoing adenosine to inosine (A-to-I) RNA editing were discovered in non-coding regions of human cerebral transcripts, particularly in genetic transposable elements called retrotransposons. We review here the interaction mechanisms of RNA editing and retrotransposons and their impact on
Heinz Krestel   +2 more
openaire   +5 more sources

The complex genome and adaptive evolution of polyploid Chinese pepper (Zanthoxylum armatum and Zanthoxylum bungeanum)

open access: yesPlant Biotechnology Journal, Volume 21, Issue 1, Page 78-96, January 2023., 2023
Summary Zanthoxylum armatum and Zanthoxylum bungeanum, known as ‘Chinese pepper’, are distinguished by their extraordinary complex genomes, phenotypic innovation of adaptive evolution and species‐special metabolites. Here, we report reference‐grade genomes of Z. armatum and Z. bungeanum.
Lisong Hu   +20 more
wiley   +1 more source

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