Mixtures of strategies underlie rodent behavior during reversal learning. [PDF]
PLoS Comput Biol, 2023 In reversal learning tasks, the behavior of humans and animals is often assumed to be uniform within single experimental sessions to facilitate data analysis and model fitting.
Le NM +5 more
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Scientific Reports, 2021 Cognitive flexibility describes the ability of animals to alter cognitively mediated behaviour in response to changing situational demands, and can vary according to prevailing environemental conditions and individual caracteristics. In the present study,
Céline Rochais +2 more
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Post-training depletions of basolateral amygdala serotonin fail to disrupt discrimination, retention, or reversal learning [PDF]
Frontiers in Neuroscience, 2015 In goal-directed pursuits, the basolateral amygdala (BLA) is critical in learning about changes in the value of rewards. BLA-lesioned rats show enhanced reversal learning, a task employed to measure the flexibility of response to changes in reward ...
G. Jesus eOchoa +5 more
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PLoS ONE, 2021 Although several studies showed adverse neurotoxic effects of melamine on hippocampus (HPC)-dependent learning and reversal learning, the evidence for this mechanism is still unknown.
Wei Sun +4 more
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Reversal learning is influenced by cognitive flexibility and develops throughout early adolescence [PDF]
npj Science of LearningLearning behavioural responses and adapting them based on feedback is crucial from a young age, continuing to develop into young adulthood. This study examines the development trajectory and contributing factors from childhood to adulthood using a ...
Christoph Bamberg +2 more
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Dopamine release in human associative striatum during reversal learning. [PDF]
Nat CommunThe dopaminergic system is firmly implicated in reversal learning but human measurements of dopamine release as a correlate of reversal learning success are lacking.
Grill F +6 more
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Prefrontal serotonin depletion delays reversal learning and increases theta synchronization of the infralimbic-prelimbic-orbitofrontal prefrontal cortex circuit [PDF]
Frontiers in PharmacologyIntroductionPrefrontal serotonin plays a role in the expression of flexible behavior during reversal learning tasks as its depletion delays reversal learning.
Yoana Estrada-Reyes +4 more
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Neural dynamics of reversal learning in the prefrontal cortex and recurrent neural networks [PDF]
eLifeIn probabilistic reversal learning, the choice option yielding reward with higher probability switches at a random trial. To perform optimally in this task, one has to accumulate evidence across trials to infer the probability that a reversal has ...
Christopher M Kim +2 more
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Sustained MK-801 induced deficit in a novel probabilistic reversal learning task [PDF]
Frontiers in Pharmacology, 2022 Cognitive flexibility, the ability to adapt to unexpected changes, is critical for healthy environmental and social interactions, and thus to everyday functioning.
Patrick Latuske +4 more
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Inhibition of midbrain cholinergic neurons impairs decision-making strategies during reversal learning [PDF]
Frontiers in Molecular NeuroscienceIntroductionThe pedunculopontine nucleus (PPN) plays a role in coordinating complex behaviors and adapting to changing environmental conditions. The specific role of cholinergic neurons in PPN function is not well understood, but their ascending ...
Yuwoong Kim +3 more
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