Results 31 to 40 of about 5,958,314 (335)

Reverse hierarchies and sensory learning [PDF]

Philosophical Transactions of the Royal Society B: Biological Sciences, 2008
Revealing the relationships between perceptual representations in the brain and mechanisms of adult perceptual learning is of great importance, potentially leading to significantly improved training techniques both for improving skills in the general population and for ameliorating deficits in special populations.
Merav, Ahissar, Mor, Nahum, Israel, Nelken, Shaul, Hochstein   +3 more
openaire   +2 more sources

Parallel learning and cognitive flexibility impairments between Fmr1 knockout mice and individuals with fragile X syndrome

Frontiers in Behavioral Neuroscience, 2023
IntroductionFragile X Syndrome (FXS) is a monogenic condition that leads to intellectual disability along with behavioral and learning difficulties. Among behavioral and learning difficulties, cognitive flexibility impairments are among the most commonly
Lauren M. Schmitt, Lauren M. Schmitt, Anna L. Arzuaga, Ashley Dapore, Jason Duncan, Maya Patel, John R. Larson, Craig A. Erickson, Craig A. Erickson, John A. Sweeney, Michael E. Ragozzino   +10 more
doaj   +1 more source

Reward and punishment reversal-learning in major depressive disorder.

Journal of Abnormal Psychology, 2020
Depression has been associated with impaired reward and punishment processing, but the specific nature of these deficits is still widely debated. We analyzed reinforcement-based decision making in individuals with major depressive disorder (MDD) to ...
D. Mukherjee, Alex Filipowicz, Khoi Vo, T. Satterthwaite, J. Kable   +4 more
semanticscholar   +1 more source

Strains and stressors: an analysis of touchscreen learning in genetically diverse mouse strains.

PLoS ONE, 2014
Touchscreen-based systems are growing in popularity as a tractable, translational approach for studying learning and cognition in rodents. However, while mouse strains are well known to differ in learning across various settings, performance variation ...
Carolyn Graybeal, Munisa Bachu, Khyobeni Mozhui, Lisa M Saksida, Timothy J Bussey, Erica Sagalyn, Robert W Williams, Andrew Holmes   +7 more
doaj   +1 more source

Deletion of the trpc4 gene and its role in simple and complex strategic learning [PDF]

, 2012
The TRPC4 ion channel is expressed extensively in corticolimbic and a subpopulation of midbrain dopamine neurons. While TRPC4 knockout (KO) rats exhibit reduced sociability and social exploration, little is known about the role of TRPC4 in motivation and
Abby Drish, Bridget Deeney, Claire Williamson, Donald Cooper, Donald Cooper, Eric Ostertag, Jessica Stumme, Kami Wenzel, Laura Swenson, Marissa Collins, Phuong Nguyen, William Klipec   +11 more
core   +2 more sources

Basal ganglia role in learning rewarded actions and executing previously learned choices: Healthy and diseased states [PDF]

, 2020
The basal ganglia (BG) is a collection of nuclei located deep beneath the cerebral cortex that is involved in learning and selection of rewarded actions. Here, we analyzed BG mechanisms that enable these functions.
Atwood, Brady, Kuznetsov, Alexey, Mulcahy, Garrett   +2 more
core   +1 more source

Dorsal and ventral striatal dopamine D1 and D2 receptors differentially modulate distinct phases of serial visual reversal learning

Neuropsychopharmacology, 2020
Impaired cognitive flexibility in visual reversal-learning tasks has been observed in a wide range of neurological and neuropsychiatric disorders. Although both human and animal studies have implicated striatal D2-like and D1-like receptors (D2R; D1R) in
Júlia Sala-Bayo, Leanne Fiddian, S. Nilsson, M. E. Hervig, C. Mckenzie, Alexis Mareschi, M. Boulos, P. Zhukovsky, J. Nicholson, J. Dalley, J. Alsiö, T. Robbins   +11 more
semanticscholar   +1 more source

Ethical Adversaries: Towards Mitigating Unfairness with Adversarial Machine Learning [PDF]

, 2020
Machine learning is being integrated into a growing number of critical systems with far-reaching impacts on society. Unexpected behaviour and unfair decision processes are coming under increasing scrutiny due to this widespread use and its theoretical ...
Berendt, Bettina, Delobelle, Pieter, Frénay, Benoît, Heymans, Patrick, Perrouin, Gilles, Temple, Paul   +5 more
core   +5 more sources

Multiple reversal olfactory learning in honeybees [PDF]

Frontiers in Behavioral Neuroscience, 2010
In multiple reversal learning, animals trained to discriminate a reinforced from a non-reinforced stimulus are subjected to various, successive reversals of stimulus contingencies (e.g. A+ vs. B-, A- vs. B+, A+ vs. B-). This protocol is useful to determine whether or not animals "learn to learn" and solve successive discriminations faster (or with ...
Theo Mota, Theo Mota, Martin Giurfa, Martin Giurfa   +3 more
openaire   +3 more sources

Neural signatures of cognitive flexibility and reward sensitivity following nicotinic receptor stimulation in dependent smokers : a randomized trial [PDF]

, 2017
IMPORTANCE Withdrawal from nicotine is an important contributor to smoking relapse. Understanding how reward-based decision making is affected by abstinence and by pharmacotherapies such as nicotine replacement therapy and varenicline tartrate may aid ...
Aronson, Sarah E., Lesage, Elise, Ross, Thomas J., Salmeron, Betty Jo, Stein, Elliot A., Sutherland, Matthew T.   +5 more
core   +2 more sources