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Molecular physiology of reverse cholesterol transport. [PDF]
Journal of Lipid Research, 1995 Reverse cholesterol transport (RCT) is the pathway by which peripheral cell cholesterol can be returned to the liver for catabolism. Evidence of specific functions for molecular structures within individual plasma lipoprotein species has rapidly ...
C J Fielding, P E Fielding
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Is reverse cholesterol transport regulated by active cholesterol?
Journal of Lipid Research, 2023 This review considers the hypothesis that a small portion of plasma membrane cholesterol regulates reverse cholesterol transport in coordination with overall cellular homeostasis.
Theodore L. Steck, Yvonne Lange
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Reverse Cholesterol Transport Pathway and Cholesterol Efflux in Diabetic Retinopathy [PDF]
Journal of Diabetes Research, 2021 Cholesterol esters, synthesized from cholesterol with long-chain fatty acids, are essential components of plasma lipoproteins and cell membranes that participate in various metabolic processes in the body.
Xinyuan Zhang +3 more
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The Regulation of Reverse Cholesterol Transport and Cellular Cholesterol Homeostasis by MicroRNAs [PDF]
Biology, 2015 MicroRNAs (miRNAs) are small, non-coding RNAs that have the ability to post-transcriptionally regulate gene expression. Hundreds of miRNAs have been identified in humans and they are involved in the regulation of almost every process, including ...
Diana M. DiMarco, Maria Luz Fernandez
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The Role of Macrophage Lipophagy in Reverse Cholesterol Transport [PDF]
Endocrinology and Metabolism, 2017 Macrophage cholesterol efflux is a central step in reverse cholesterol transport, which helps to maintain cholesterol homeostasis and to reduce atherosclerosis.
Se-Jin Jeong, Mi-Ni Lee, Goo Taeg Oh
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Reverse Cholesterol Transport [PDF]
Cor et Vasa, 2006 Atherosclerosis, the accumulation of cholesterol in the arteries resulting in heart attacks and strokes, is the leading cause of death in the USA and most other industrialized countries in the world. Plasma levels of high-density lipoprotein (HDL) cholesterol are invariably found to be inversely associated with the risk of atherosclerosis.
Daniel L. Sparks +4 more
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Cardiovascular Therapeutics, 2022 Hyperlipidemia characterized by abnormal deposition of cholesterol in arteries can cause atherosclerosis and coronary artery occlusion, leading to atherosclerotic coronary heart disease.
Xiuting Xu +3 more
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On measuring the bending modulus of lipid bilayers with cholesterol [PDF]
Phys. Rev. E 104, 044405 (2021), 2021 Regarding the effect on the bending modulus of adding cholesterol to lipid bilayers, recent results using neutron spin echo and nuclear magnetic resonance relaxation methods that involve linear transport properties have conflicted with earlier results from purely equilibrium experiments that do not involve linear transport properties.
arxiv +1 more source
HDL Functions—Current Status and Future Perspectives
Biomolecules, 2023 Cardiovascular disease (CVD) is the leading cause of death in Western countries. A low HDL-C is associated with the development of CVD. However, recent epidemiology studies have shown U-shaped curves between HDL-C and CVD mortality, with paradoxically ...
Yasuhiro Endo +2 more
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Cholesterol Efflux and Reverse Cholesterol Transport [PDF]
, 2014 Both alterations of lipid/lipoprotein metabolism and inflammatory events contribute to the formation of the atherosclerotic plaque, characterized by the accumulation of abnormal amounts of cholesterol and macrophages in the artery wall. Reverse cholesterol transport (RCT) may counteract the pathogenic events leading to the formation and development of ...
FAVARI, Elda +5 more
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