Results 11 to 20 of about 124,891 (298)
HDL and Reverse Cholesterol Transport. [PDF]
Circ Res, 2019 Cardiovascular disease, with atherosclerosis as the major underlying factor, remains the leading cause of death worldwide. It is well established that cholesterol ester-enriched foam cells are the hallmark of atherosclerotic plaques.
Ouimet M, Barrett TJ, Fisher EA.
europepmc +4 more sources
Apoprotein E and Reverse Cholesterol Transport. [PDF]
Int J Mol Sci, 2018 Apoprotein E (apoE) is a multifunctional protein. Its best-characterized function is as a ligand for low-density lipoprotein (LDL) receptor family members to mediate the clearance of apoB-containing atherogenic lipoproteins.
Getz GS, Reardon CA.
europepmc +5 more sources
Reverse cholesterol transport and hepatic osteodystrophy. [PDF]
Cell Metab, 2022 In this issue of Cell Metabolism, Lu et al. show that chronic liver disease increases the expression and activity of PP2Ac, a phosphatase that downregulates the excretion of lecithin-cholesterol aceyltransferase (LCAT). LCAT, a liver-derived enzyme, protects bone and prevents bone loss, and its lowered levels in progressive liver injury cause hepatic ...
Zaidi M, Yuen T, Iqbal J.
europepmc +4 more sources
HDL and Reverse Cholesterol Transport Biomarkers. [PDF]
Methodist Debakey Cardiovasc J, 2019 High-density lipoprotein (HDL) is a protein-lipid nanoparticle that has predominately been characterized by its cholesterol concentration (HDL-C). Recent studies have challenged the presumed inverse association between HDL-C and cardiovascular events ...
Riggs KA, Rohatgi A.
europepmc +5 more sources
Reverse Cholesterol Transport and Atherosclerosis. [PDF]
Arterioscler Thromb Vasc Biol, 2019 Despite improvements in atherosclerotic cardiovascular disease (ASCVD) by targeting reduction of apoBcontaining lipoproteins, ASCVD remains the leading cause of death.
Rohatgi A.
europepmc +6 more sources
Cancer Prevention Research, 2019 Chronic obstructive pulmonary disease (COPD) and lung cancer share the same etiologic factor, cigarette smoking. Higher consumption of dietary lycopene has been associated with lower risks of COPD and lung cancer in smokers.
Jelena Mustra Rakic +7 more
semanticscholar +3 more sources
LDL Contributes to Reverse Cholesterol Transport. [PDF]
Circulation Research, 2020 To explain the atherogenicity and the antiatherogenicity of LDLs (low-density lipoproteins) and HDLs (high-density lipoproteins), respectively, many students and patients are taught that LDLs deliver cholesterol from liver to peripheral cells, whereas ...
A. von Eckardstein
semanticscholar +4 more sources
Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport
Nature Communications, 2017 Activation of brown adipose tissue (BAT) reduces the development of atherosclerosis in animal models. Here the authors show that BAT activation also increases reverse cholesterol transport and turnover of high-density lipoprotein, which likely ...
Alexander Bartelt +19 more
doaj +2 more sources
Frontiers in Physiology, 2018 Dyslipidemia (high concentrations of LDL-c and low concentrations of HDL-c) is a major cause of cardiovascular events, which are the leading cause of death in the world.
Leandro R. Marques +6 more
doaj +2 more sources
Anacetrapib promotes reverse cholesterol transport and bulk cholesterol excretion in Syrian golden hamsters [PDF]
Journal of Lipid Research, 2011 Cholesteryl ester transfer protein (CETP) transfers cholesteryl ester (CE) and triglyceride between HDL and apoB-containing lipoproteins. Anacetrapib (ANA), a reversible inhibitor of CETP, raises HDL cholesterol (HDL-C) and lowers LDL cholesterol in ...
Jose Castro-Perez +12 more
doaj +2 more sources