Results 21 to 30 of about 113,812 (280)
Physical Fitness and Reverse Cholesterol Transport [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2004 Background— Physical exercise is associated with a decreased risk of cardiovascular disease, which may be partly caused by the effect of exercise on the lipoprotein profile. The most consistent effect of exercise on lipoprotein metabolism is an increase in high-density lipoprotein (HDL).
Anh Hoang +6 more
openaire +3 more sources
The Structure of Cholesterol in Lipid Rafts [PDF]
Physical Review Letters 113, 228101 (2014), 2014 Rafts, or functional domains, are transient nano- or mesoscopic structures in the plasma membrane and are thought to be essential for many cellular processes such as signal transduction, adhesion, trafficking and lipid/protein sorting. Observations of these membrane heterogeneities have proven challenging, as they are thought to be both small and short-
arxiv +1 more source
Acrolein impairs the cholesterol transport functions of high density lipoproteins. [PDF]
PLoS ONE, 2015 High density lipoproteins (HDL) are considered athero-protective, primarily due to their role in reverse cholesterol transport, where they transport cholesterol from peripheral tissues to the liver for excretion.
Alexandra C Chadwick +7 more
doaj +1 more source
Effects of flavonoids on cholesterol efflux capability
International Journal of Medical Biochemistry, 2022 Reverse cholesterol transport (RCT), which plays a critical role in the export of cholesterol from peripheral cells, is one of the processes employed in the management and treatment of atherosclerosis.
Maha Abdulmajeed Ayoub
doaj +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021 Background MEDI6012 is recombinant human lecithin cholesterol acyltransferase, the rate‐limiting enzyme in reverse cholesterol transport. Infusions of lecithin cholesterol acyltransferase have the potential to enhance reverse cholesterol transport and ...
Richard T. George +10 more
doaj +1 more source
Research, 2023 Spinal cord injury triggers complex pathological cascades, resulting in destructive tissue damage and incomplete tissue repair. Scar formation is generally considered a barrier for regeneration in the central nervous system.
Bolin Zheng +8 more
doaj +1 more source
High density lipoprotein – a hero, a mirage or a witness?
Frontiers in Cardiovascular Medicine, 2014 Negative relationship between plasma High Density Lipoprotein (HDL) levels and risk of cardiovascular disease is a firmly established medical fact, but attempts to reproduce protective properties of HDL by pharmacologically elevating HDL levels were ...
Dmitri eSviridov
doaj +1 more source
Utilizing the LoxP-Stop-LoxP System to Control Transgenic ABC-Transporter Expression In Vitro
Biomolecules, 2022 ABCA1 and ABCG1 are two ABC-transporters well-recognized to promote the efflux of cholesterol to apoAI and HDL, respectively. As these two ABC-transporters are critical to cholesterol metabolism, several studies have assessed the impact of ABCA1 and ...
Ikechukwu Esobi +3 more
doaj +1 more source
HDL and Reverse Cholesterol Transport [PDF]
Circulation Research, 2019 Cardiovascular disease, with atherosclerosis as the major underlying factor, remains the leading cause of death worldwide. It is well established that cholesterol ester-enriched foam cells are the hallmark of atherosclerotic plaques. Multiple lines of evidence support that enhancing foam cell cholesterol efflux by HDL (high-density lipoprotein ...
Tessa J. Barrett +2 more
openaire +3 more sources
P2Y13 Receptor Is Critical for Reverse Cholesterol Transport [PDF]
Hepatology, 2010 A major atheroprotective functionality of high-density lipoproteins (HDLs) is to promote “reverse cholesterol transport” (RCT). In this process, HDLs mediate the efflux and transport of cholesterol from peripheral cells and its subsequent transport to the liver for further metabolism and ...
Niels Nijstad +26 more
openaire +5 more sources