Results 231 to 240 of about 2,173,029 (360)

Establishment of a reverse genetics system for studying human immune functions in mice. [PDF]

Sci Adv
Pal P, Gao S, Gao H, Qin X, Cella M, Wang Q, Shan L.   +6 more
europepmc   +1 more source

Reverse Genetics Recovery of Lujo Virus and Role of Virus RNA Secondary Structures in Efficient Virus Growth [PDF]

, 2012
Éric Bergeron, Ayan K. Chakrabarti, Brian H. Bird, Kim A. Dodd, Laura K. McMullan, Christina F. Spiropoulou, Stuart T. Nichol, César G. Albariño   +7 more
openalex   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Rotavirus Reverse Genetics Systems and Oral Vaccine Delivery Vectors for Mucosal Vaccination. [PDF]

Microorganisms
Wang J, Qin S, Li K, Yin X, Sun D, Chang J.   +5 more
europepmc   +1 more source

Reverse Genetics Screen in Zebrafish Identifies a Role of miR-142a-3p in Vascular Development and Integrity

, 2012
Mukesh Kumar Lalwani, Meenakshi Sharma, Angom Ramcharan Singh, Rajendra Chauhan, Ashok Patowary, Naresh Singh, Vinod Scaria, Sridhar Sivasubbu   +7 more
openalex   +2 more sources

Reverse Genetics with a Full-Length Infectious cDNA Clone of Bovine Torovirus

, 2021
Makoto Ujike, Yuka Etoh, Naoya Urushiyama, Fumihiro Taguchi, Hideki Asanuma, Luis Enjuanes, Wataru Kamitani   +6 more
openalex   +2 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Reverse genetics study disclaims the role of African swine fever virus gene I196L in the pathogenesis in pigs. [PDF]

J Vet Med Sci
Yoshimoto A, Kitamura T, Ikezawa M, Kokuho T, Masujin K.   +4 more
europepmc   +1 more source

Reverse genetics systems for SARS-CoV-2: Development and applications. [PDF]

Virol Sin, 2023
Cai HL, Huang YW.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source