Results 171 to 180 of about 125,916 (291)

Human Immunodeficiency Virus Mutagenesis during Antiviral Therapy: Impact of Drug-Resistant Reverse Transcriptase and Nucleoside and Nonnucleoside Reverse Transcriptase Inhibitors on Human Immunodeficiency Virus Type 1 Mutation Frequencies

, 2005
Renxiang Chen, Masaru Yokoyama, Hironori Sato, Cavan Reilly, Louis M. Mansky   +4 more
openalex   +1 more source

Mucin Glycoprotein Nanoparticles Enable a Selective Antisense Therapy for Oncogenic MicroRNAs

Advanced NanoBiomed Research, EarlyView.
Mucin glycoproteins are turned into nanoparticles by employing synthetic DNA strands, which have a dual function: they stabilize the nanoparticles and act as binding sites for intracellular miRNA‐21. Thus, upon internalization into tumor cells, these mucin nanoparticles can deplete miRNA‐21 from the cytosol, which induces apoptosis in vitro and in vivo.
Ceren Kimna, Thomas Mayer, Di Zhang, Matthias Marczynski, Carolin A. Rickert, Fabio Henkel, Lennart J. K. Weiss, Friedrich C. Simmel, Yuxia Luan, Oliver Lieleg   +9 more
wiley   +1 more source

An Exploratory Pharmacogenetic Pilot Study of Two Reverse Transcriptase Inhibitors, Tenofovir Alafenamide Fumarate and Tenofovir Disoproxil Fumarate. [PDF]

Drugs R D
Murrell DE, Kennard BC, Bertoni ME, Cluck DB, Moorman JP, Brown SD, Wang K, Duffourc MM, Harirforoosh S.   +8 more
europepmc   +1 more source

Nucleoside reverse transcriptase inhibitors are anti-inflammatory and inhibit poly I:C-induced retinal pigment epithelium degeneration

, 2016
Shin‐ichi Fukuda, Junichi Fukuhara, Younghee Kim, Benjamin J. Fowler, Tetsuhiro Yasuma, Reo Yasuma, Takako Fukuhara, Nagaraj Kerur, Bradley D. Gelfand, Jayakrishna Ambati   +9 more
openalex   +1 more source

Role of Ligand Reorganization and Conformational Restraints on the Binding Free Energies of DAPY Non-Nucleoside Inhibitors to HIV Reverse Transcriptase

, 2012
Emilio Gallicchio
openalex   +2 more sources

Discovery of Dual Targeting GSK-3β/HIV-1 Reverse Transcriptase Inhibitors as Neuroprotective Antiviral Agents. [PDF]

ACS Chem Neurosci
Jones T, Raman R, Puhl AC, Lane TR, Riabova O, Kazakova E, Makarov V, Ekins S.   +7 more
europepmc   +1 more source

Identification of Boronate-Containing Diarylpyrimidine Derivatives as Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors. [PDF]

Molecules, 2022
Feng D, Lin H, Jiang L, Wang Z, Sun Y, Zhou Z, Clercq E, Pannecouque C, Kang D, Zhan P, Liu X.   +10 more
europepmc   +1 more source

High-throughput sequence analysis reveals structural diversity and improved potency among RNA inhibitors of HIV reverse transcriptase [PDF]

, 2012
Mark A. Ditzler, Margaret J. Lange, Debojit Bose, Christopher A. Bottoms, Katherine F. Virkler, Andrew W. Sawyer, Angela S. Whatley, William G. Spollen, Scott A. Givan, Donald H. Burke   +9 more
openalex   +1 more source

Synthesis of novel N1 functionalized diazepinone analogues <i>via</i> a base-mediated C-N cross coupling reaction as reverse transcriptase inhibitors: theoretical and experimental investigations. [PDF]

RSC Adv
Jaiswal S, Jain S, Mukhija A, Verma K, Jain S, Kishore D, Dwivedi J, Sharma S.   +7 more
europepmc   +1 more source

Resistance levels to non-nucleoside reverse transcriptase inhibitors among pregnant women with recent HIV infection in Malawi. [PDF]

Antivir Ther, 2022
Bello G, Kagoli M, Chipeta S, Auld A, Chang JC, DeVos JR, Kim E, Mkungudza J, Payne D, Eliya M, Nyirenda R, Jahn A, Mzumara T, Mvula B, Dadabhai S, Namakhoma I, Babaye Y, Giron A, Jordan MR, Bertagnolio S, O'Malley G, Wadonda-Kabondo N.   +21 more
europepmc   +1 more source