Results 211 to 220 of about 399,014 (392)

High prevalence and incidence of HIV-1 in a counseling and testing center in the city of Itajaí, Brazil

Brazilian Journal of Infectious Diseases, 2015
Itajaí is a port city in southern Brazil with one of the highest incidence and mortality rates from AIDS in the country. The prevalence and incidence of HIV infection were investigated in 1085 of 3196 new HIV-1 infection cases evaluated in the counseling
Gorki Grinberg, Leila Bertoni Giron, Rosalie Kupka Knoll, Juliana Galinskas, Michelle Camargo, Muhammad Shoaib Arif, Sadia Samer, Luiz Mario Ramos Janini, Maria Cecilia Araripe Sucupira, Ricardo Sobhie Diaz   +9 more
doaj  

Susceptibility of Human Endogenous Retrovirus Type K to Reverse Transcriptase Inhibitors

Journal of Virology, 2017
Rafael Contreras-Galindo, Derek Dube, K. Fujinaga, M. Kaplan, D. Markovitz   +4 more
semanticscholar   +1 more source

Inflammatory response to retrotransposons drives tumor drug resistance that can be prevented by reverse transcriptase inhibitors. [PDF]

Proc Natl Acad Sci U S A, 2022
Novototskaya-Vlasova KA, Neznanov NS, Molodtsov I, Hall BM, Commane M, Gleiberman AS, Murray J, Haber M, Norris MD, Leonova KI, Gudkov AV.   +10 more
europepmc   +1 more source

Annual Banned‐Substance Review 17th Edition—Analytical Approaches in Human Sports Drug Testing 2023/2024

Drug Testing and Analysis, EarlyView.
Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario  Thevis, Tiia  Kuuranne, Hans  Geyer   +2 more
wiley   +1 more source

A Novel Genotype Encoding a Single Amino Acid Insertion and Five Other Substitutions Between Residues 64 and 74 of the HIV-1 Reverse Transcriptase Confers High-Level Cross-Resistance to Nucleoside Reverse Transcriptase Inhibitors

, 1999
Abdelrahim Rakik, Mounir Ait‐Khaled, Philip Griffin, Deborah A. Thomas, Margaret Tisdale, Jőrg‐Peter Kleim   +5 more
openalex   +1 more source

Immunogenicity of Mutations Induced by Nucleoside Reverse Transcriptase Inhibitors for Human Immunodeficiency Virus Type 1-Specific Cytotoxic T Cells [PDF]

, 2000
Assia Samri, Gaby Haas, Joerg Duntze, Jean-Marc Bouley, Vincent Cálvez, Christine Katlama, Brigitte Autran   +6 more
openalex   +1 more source

Protein turnover downstream of the Nipbl/CRL4 axis contributes to abnormal development in zebrafish embryos

Developmental Dynamics, EarlyView.
Abstract Background Mutations in cohesins cause cohesinopathies such as Cornelia de Lange Syndrome (CdLS) and Roberts Syndrome (RBS). Prior findings demonstrate that Esco2 (a cohesin activator) and Smc3 (a core cohesin subunit) regulate the CRL4 E3 ubiquitin ligase. SMC3 mutations, however, account for a small percentage of CdLS.
Annie C. Sanchez, Niusha Banoukh, Fiona Mensching, Robert V. Skibbens, M. Kathryn Iovine   +4 more
wiley   +1 more source

Substitution of a Nonnucleoside Reverse Transcriptase Inhibitor for a Protease Inhibitor in the Treatment of Patients with Undetectable Plasma Human Immunodeficiency Virus Type 1 RNA [PDF]

, 2000
François Raffi, Benjamin Bonnet, Valentine Marie Ferré, J.-L. Esnault, Philippe Van de Perre, Véronique Reliquet, S Léautez, C. Bouillant, O. Vergnoux, P. Weinbreck   +9 more
openalex   +1 more source

Identification of Boronate-Containing Diarylpyrimidine Derivatives as Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors. [PDF]

Molecules, 2022
Feng D, Lin H, Jiang L, Wang Z, Sun Y, Zhou Z, Clercq E, Pannecouque C, Kang D, Zhan P, Liu X.   +10 more
europepmc   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source