Results 211 to 220 of about 125,916 (291)

An Amazing 30-Year Journey around the DABO Family: A Medicinal Chemistry Lesson on a Versatile Class of Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors. [PDF]

J Med Chem
Fabbrizi E, Chernyshov VV, Fiorentino F, Sbardella G, Ragno R, Nawrozkij M, Ivanov R, Rotili D, Mai A.   +8 more
europepmc   +1 more source

Efavirenz Has the Highest Anti-Proliferative Effect of Non-Nucleoside Reverse Transcriptase Inhibitors against Pancreatic Cancer Cells

, 2015
Markus Hecht, Sonja Erber, Thomas Harrer, Hartwig Klinker, Thomas Roth, Hans Parsch, Nora Fiebig, Rainer Fietkau, Luitpold Distel   +8 more
openalex   +2 more sources

Epigenetic inflammatory memory and periodontal disease: Mechanisms and clinical significance for comorbidities

Journal of Periodontology, EarlyView.
Abstract Historically, immunological memory was considered an exclusive feature of adaptive immunity. However, innate immune cells have recently been shown to record and maintain epigenetically imprinted memory of earlier infectious or inflammatory challenges.
George Hajishengallis
wiley   +1 more source

Comprehensive Chemical Analysis of the Methyl 3-Nitrogen-2,3-Dideoxysaccharides Derivatives with d-<i>ribo</i>-Configuration: Synthesis, Reactivity of HIV-1 Reverse Transcriptase Inhibitors. [PDF]

J Phys Chem B
Dąbrowska AM, Kaźmierkiewicz R, Barabaś-Lepak AM, Biedulska M, Chylewska A.   +4 more
europepmc   +1 more source

Low Cerebrospinal Fluid Concentrations of the Nucleotide HIV Reverse Transcriptase Inhibitor, Tenofovir

, 2012
Brookie M. Best, Scott Letendre, Peter J. Koopmans, Steven S. Rossi, David B. Clifford, Ann C. Collier, Benjamin B. Gelman, Christina M. Marra, Justin C. McArthur, J. Allen McCutchan, Susan Morgello, David M. Simpson, Edmund V. Capparelli, Ronald J. Ellis, Igor Grant   +14 more
openalex   +2 more sources

Brief Report: Protease Inhibitors Versus Nonnucleoside Reverse Transcriptase Inhibitors and the Risk of Cancer Among People With HIV. [PDF]

J Acquir Immune Defic Syndr
Coburn SB, Pimentel N, Leyden W, Kitahata MM, Moore RD, Althoff KN, Gill MJ, Lang R, Horberg MA, D'Souza G, Hussain SK, Dubrow R, Novak RM, Rabkin CS, Park LS, Sterling TR, Neugebauer RS, Silverberg MJ, North American AIDS Cohort Collaboration on Research and Design of the International Epidemiologic Databases to Evaluate AIDS.   +18 more
europepmc   +1 more source

In Silico Screening for Non‐nucleoside HIV‐1 Reverse Transcriptase Inhibitors Using Physicochemical Filters and High‐Throughput Docking Followed by In Vitro Evaluation

, 2009
Yasser Bustanji, Ihab M. Almasri, Ahmad Qasem, Amal G. Al‐Bakri, Mutasem O. Taha   +4 more
openalex   +1 more source

Role of COL1A1 and CD44 in Modulating JAK1/STAT3‐Mediated Autophagy for Spinal Cord Injury Recovery

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Spinal cord injury (SCI) is a severe trauma to the central nervous system that often leads to motor and sensory dysfunction in patients, severely affecting their quality of life. Autophagy plays a role in the pathological process of SCI, but the specific mechanism of autophagy in this case is unknown.
Chun‐Lei Li, Qian Zhang, Li Fang, Ling‐Yun Zhou   +3 more
wiley   +1 more source

Reverse transcriptase inhibitors prevent liver abscess formation during Escherichia coli bloodstream infection. [PDF]

Proc Natl Acad Sci U S A
Hullahalli K, Dailey KG, Hasegawa Y, Johnson WE, Waldor MK.   +4 more
europepmc   +1 more source

CRISPR Enabled Precision Oncology: From Gene Editing to Tumor Microenvironment Remodeling

Med Research, EarlyView.
CRISPR technology has progressed from a prokaryotic immune system to a diverse suite of editing platforms, including Cas nucleases, base and prime editors, and RNA‐targeting enzymes. These advances enable precise genomic and epigenomic interventions, high‐throughput functional screening, and immune engineering.
Kailai Li, Peixin Huang, Yue Qian, Anqi Lin, Jingjun He, Junyi Shen, Li Chen, Kai Miao, Jian Zhang   +8 more
wiley   +1 more source