Results 71 to 80 of about 142 (121)

Exploring the Depths of Cryptic Aspergillosis: Species Variability, Clinical Spectrum, Diagnostic Quandaries and Therapeutic Options [PDF]

Journal of Clinical and Diagnostic Research
Cryptic aspergillosis, characterised by infections caused by non classical Aspergillus species, presents unique challenges in clinical management due to species variability, diverse clinical manifestations, diagnostic complexities, and limited treatment ...
Almas Fathima Upaisal, Anupma Jyoti Kindo   +1 more
doaj   +1 more source

The Candida auris Infection After the COVID‐19 Pandemic Seems to be an Urgent Public Health Emergency: A Call to Attention

Health Science Reports, Volume 7, Issue 11, November 2024.
Abstract Background and Aims Inconsequential diseases can sometimes become extremely dangerous through mutation. Antifungal resistance has increased by 24%, and resistance only due to Candida auris (C. auris) species have increased by 60%. Here, we aimed to assess the knowledge of antifungal treatment and preventative measures to mitigate the ...
Md. Ashrafur Rahman, Evangelos Victoros, Yeasna Shanjana, Marie Roke Thomas, Md. Rabiul Islam   +4 more
wiley   +1 more source

The In Vitro Activity of Rezafungin Against Uncommon Species of Candida

Mycoses
ABSTRACTBackgroundInvasive candidiasis (IC) is increasing due to the rising numbers of immunocompromised patients. Increasing azole resistance rates and daily dosing required for most echinocandins have complicated its treatment. The approval of rezafungin has provided an option for weekly echinocandin treatment.
Marisa L. Winkler, Paul Rhomberg, Abigail L. Klauer, Samuel Edeker, Mariana Castanheira   +4 more
openaire   +2 more sources

Management of Intra-Abdominal Candidiasis in Intensive Care Setting: A Narrative Review

Journal of Fungi
Intra-abdominal candidiasis (IAC), with or without candidemia, is a common condition in patients in intensive care units (ICUs). Early diagnosis of IAC remains a challenge for clinicians despite new biomarkers. Early and appropriate antifungal treatment,
Marco Marotta Pais, Rafael Zaragoza, Ignacio Martín-Loeches, Frederic F. Gómez-Bertomeu, Alejandro Rodríguez   +4 more
doaj   +1 more source

Fungal endocarditis: microbial insights, diagnostic and therapeutic challenges in the modern era [PDF]

Exploration of Cardiology
Fungal endocarditis (FE) is still an uncommon but devastating infection, especially when immunosuppression, prosthetic valve surgery, or prolonged health care is involved.
Sudeep Edpuganti
doaj   +1 more source

Innovative Antimykotika-Therapie und Versorgungssteuerung entlang der transsektoralen Patient-Journey

Monitor Versorgungsforschung
Invasive Pilzinfektionen wie Candidämie und invasive Candidiasis erfordern häufig langwierige stationäre Behandlungen aufgrund des kontinuierlichen Therapiebedarfs und gehen mit hohen Sterblichkeitsraten einher.
Prof. Dr. rer. medic. Florian Kron, Johanna Röder MSc, Katja Heße MSc, Dr. rer. medic. Sebastian Wingen-Heimann, Prof. Dr. rer. pol. Björn Maier, Dr. rer. nat. Nils Keiner, Prof. Dr. med. Oliver Cornely   +6 more
doaj   +1 more source

Tn-seq screens in Candida glabrata treated with echinocandins and ibrexafungerp reveal pathways of antifungal resistance and cross-resistance

mSphere
Candida glabrata (also known as Nakaseomyces glabratus) is the second most common cause of candidiasis, next to Candida albicans, and is rising in prevalence due to intrinsic and acquired mechanisms of antifungal resistance.
Timothy J. Nickels, Kyle W. Cunningham
doaj   +1 more source

The Silent Pandemic: Antifungal Resistance and the Future of Invasive Fungal Disease Management

Microorganisms
Invasive fungal diseases (IFDs) represent an escalating global health threat, compounded by the rapid emergence of antifungal resistance (AFR). This review synthesizes the contemporary landscape of AFR from clinical and microbiological perspectives ...
Ruchika Bagga, Kumudhavalli Kavanoor Sridhar   +1 more
doaj   +1 more source

Multicenter surveillance of antifungal susceptibility of clinical Aspergillus isolates to conventional and novel antifungal agents in Taiwan, 2021–2023

Microbiology Spectrum
Periodic surveillance of antifungal susceptibility among Aspergillus isolates is essential to guide effective treatment. This multicenter study analyzed 550 clinical Aspergillus isolates collected in Taiwan from 2021 to 2023, primarily from the ...
Ming-I Hsieh, Pui-Ching Choi, Wan-Lin Wu, Yu-Fu Lin, Chi-Jung Wu   +4 more
doaj   +1 more source

Antifungal Agents in the 21st Century: Advances, Challenges, and Future Perspectives

Infectious Disease Reports
Invasive fungal infections (IFIs) represent a growing global health threat, particularly for immunocompromised populations, with mortality exceeding 1.5 million deaths annually.
Francesco Branda, Nicola Petrosillo, Giancarlo Ceccarelli, Marta Giovanetti, Andrea De Vito, Giordano Madeddu, Fabio Scarpa, Massimo Ciccozzi   +7 more
doaj   +1 more source