Results 11 to 20 of about 68,233 (207)

Probable Mechanisms of Doxorubicin Antitumor Activity Enhancement by Ginsenoside Rh2

open access: yesMolecules, 2022
Ginsenoside Rh2 increases the efficacy of doxorubicin (DOX) treatment in murine models of solid and ascites Ehrlich’s adenocarcinoma. In a solid tumor model (treatment commencing 7 days after inoculation), DOX + Rh2 co-treatment was significantly more ...
Alexander Popov   +14 more
doaj   +1 more source

How Does Ginsenoside Rh2 Mitigate Adipogenesis in Cultured Cells and Obese Mice?

open access: yesMolecules, 2020
Ginsenoside Rh2, an intermediate metabolite of ginseng, but not naturally occurring, has recently drawn attention because of its anticancer effect. However, it is not clear if and how Rh2 inhibits preadipocytes differentiation.
Longyun Zhang   +2 more
doaj   +1 more source

Influence of Auricularia cornea Polysaccharide Coating on the Stability and Antioxidant Activity of Liposomes Ginsenoside Rh2

open access: yesFoods, 2023
Liposomes (Lip) are microstructures containing lipid and aqueous phases for encapsulation and delivery of bioactivators. In this study, Ginsenoside Rh2 liposomes (Rh2−Lip) were prepared by a thin-film hydrated ultrasonic binding method.
Minghui Wang   +6 more
doaj   +1 more source

Anticancer activity of ginsenosides Rh2 on various cancer cells

open access: yesJournal of Animal Reproduction and Biotechnology, 2023
Background: This study has mainly focused on finding pharmacological effects of ginsenosides that can reduce the unwanted side effects of the cytotoxic anticancer drugs and are highly effective on prostate cancer, colorectal cancer, liver cancer, hormone-
Seun Eui Kim   +6 more
doaj   +1 more source

Increased antitumor efficacy of ginsenoside Rh2 via mixed micelles: in vivo and in vitro evaluation

open access: yesDrug Delivery, 2020
The aim of this work is to apply Solutol® HS15 and TPGS to prepare self-assembled micelles loading with ginsenoside Rh2 to increase the solubility of ginsenoside Rh2, hence, improving the antitumor efficacy.
Xiaojing Xia   +5 more
doaj   +1 more source

In vivo study of anticancer activity of ginsenoside Rh2-containing arginine-reduced graphene in a mouse model of breast cancer [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2022
Objective(s): This study aims to evaluate the in vivo anticancer activity of arginine-reduced graphene (Gr-Arg) and ginsenoside Rh2-containing arginine-reduced graphene (Gr-Arg-Rh2).
Shervindokht Farhangfar   +7 more
doaj   +1 more source

Glycosyltransformation of ginsenoside Rh2 into two novel ginsenosides using recombinant glycosyltransferase from Lactobacillus rhamnosus and its in vitro applications

open access: yesJournal of Ginseng Research, 2021
Background: Ginsenoside Rh2 is well known for many pharmacological activities, such as anticancer, antidiabetes, antiinflammatory, and antiobesity properties. Glycosyltransferases (GTs) are ubiquitous enzymes present in nature and are widely used for the
Dan-Dan Wang   +7 more
doaj   +1 more source

Spatially differentiated expression of quadruplicated green-sensitive RH2 opsin genes in zebrafish is determined by proximal regulatory regions and gene order to the locus control region [PDF]

open access: yes, 2015
BACKGROUND: Fish are remarkably diverse in repertoires of visual opsins by gene duplications. Differentiation of their spatiotemporal expression patterns and absorption spectra enables fine-tuning of feature detection in spectrally distinct regions of ...
Ryoko Masuda   +3 more
core   +1 more source

Ginsenoside Rh2 Ameliorates Neuropathic Pain by inhibition of the miRNA21-TLR8-mitogen-activated protein kinase axis

open access: yesMolecular Pain, 2022
Ginsenoside Rh2 is one of the major bioactive ginsenosides in Panax ginseng . Although Rh2 is known to enhance immune cells activity for treatment of cancer, its anti-inflammatory and neuroprotective effects have yet to be determined.
Yuan-Yuan Fu   +5 more
doaj   +1 more source

Ginsenoside Rh2 inhibits breast cancer cell growth viaERβ-TNFα pathway

open access: yesActa Biochimica et Biophysica Sinica, 2022
Ginsenoside Rh2 is one of rare panaxidiols extracted from Panax ginseng and a potential estrogen receptor ligand that exhibits moderate estrogenic activity.
Peng Kunjian   +11 more
doaj   +1 more source

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