Results 21 to 30 of about 51,297 (183)

Antiallergic Activity of Ginsenoside Rh2

Biological & Pharmaceutical Bulletin, 2003
The antiallergic activities of ginsenosides, which were isolated from acid-treated ginseng (Panax ginseng, Araliaceae), and their metabolites by human intestinal bacteria were measured. Ginsenoside Rh2, which is a main metabolite, had the most potent inhibitory activity on beta-hexosaminidase release from RBL-2H3 cells and in the passive cutaneous ...
Park, Eun-Kyung, Choo, Min-Kyung, Kim, Eun-Jin, Han, Myung Joo, Kim, Dong-Hyun   +4 more
openaire   +3 more sources

Network Pharmacology-Based Prediction and Verification of Ginsenoside Rh2-Induced Apoptosis of A549 Cells via the PI3K/Akt Pathway

Frontiers in Pharmacology, 2022
Ginsenoside Rh2 (G-Rh2), a rare protopanaxadiol (PPD)-type triterpene saponin, from Panax ginseng has anti-proliferation, anti-invasion, and anti-metastatic activity.
Chao Song, Yue Yuan, Jing Zhou, Ziliang He, Yeye Hu, Yuan Xie, Nan Liu, Lei Wu, Ji Zhang   +8 more
doaj   +1 more source

Ginsenoside Rh2 inhibits thyroid cancer cell migration and proliferation via activation of miR-524-5p

Archives of Medical Science, 2020
Introduction Thyroid cancer is an important disease that threatens the health of humans. Ginsenoside Rh2 is known as an anticancer molecule; however, its function in thyroid cancer cells has not been reported. In the present study, we identified that Rh2
Shan Jiang, Jiqi Yan, Xingsheng Chen, Qingji Xie, Wei Lin, Ting Lin, Qinyu Li   +6 more
doaj   +1 more source

Tumor cell membrane-camouflaged responsive nanoparticles enable MRI-guided immuno-chemodynamic therapy of orthotopic osteosarcoma

Bioactive Materials, 2022
Osteosarcoma is a refractory bone disease in young people that needs the updating and development of effective treatment. Although nanotechnology is widely applied in cancer therapy, poor targeting and inadequate efficiency hinder its development.
Liwen Fu, Weiying Zhang, Xiaojun Zhou, Jingzhong Fu, Chuanglong He   +4 more
doaj   +1 more source

Synergistic Effect of Ginsenoside Rh2 Combines with Ionizing Radiation on CT26/luc Colon Carcinoma Cells and Tumor-Bearing Animal Model

Pharmaceuticals, 2023
Background: The local tumor control rate of colon cancer by radiotherapy is unsatisfactory due to recurrence and radioresistance. Ginsenoside Rh2 (Rh2), a panoxadiol saponin, possesses various antitumor effects.
Shan-Chih Lee, Chao-Yu Shen, Wei-Hsun Wang, Yen-Po Lee, Keng-Wei Liang, Ying-Hsiang Chou, Yeu-Sheng Tyan, Jeng-Jong Hwang   +7 more
doaj   +1 more source

Infrared and Raman Spectroscopy of the Dirhodium Tetraacetate Complexes Rh2(O2CCH3)4, Rh2(18O2CCH3)4, Rh2(O2CCD3)4 and Rh2(O2CCH3)4(H2O)2

Croatica Chemica Acta, 1988
The infrared (3500-50 cm-I), and Raman (3550-30 cm-I) spectra of the dirhodium tetraacetate species Rh2(02CCHs)4, Rh2(IB02CCHs)4, Rh2(02CCDS)4, and Rh2(02CCHs)4(H20)2 have been recorded and the key bands assigned, The oxygen-18 and deuteration studies, in particular, assisted with ma king the important band assignments for the anhydrous complex, for ...
Clark, Robin J. H., Hempleman, Andrew J.
openaire   +3 more sources

AMP-activated protein kinase determines apoptotic sensitivity of cancer cells to ginsenoside-Rh2

Journal of Ginseng Research, 2014
Ginseng saponins exert various important pharmacological effects with regard to the control of many diseases, including cancer. In this study, the anticancer effect of ginsenosides on human cancer cells was investigated and compared.
Min-Jung Kim, Hee Yun, Dong-Hyun Kim, Insug Kang, Wonchae Choe, Sung-Soo Kim, Joohun Ha   +6 more
doaj   +1 more source

Comparative analysis of the expression level of recombinant ginsenoside-transforming β-glucosidase in GRAS hosts and mass production of the ginsenoside Rh2-Mix. [PDF]

PLoS ONE, 2017
The ginsenoside Rh2, a pharmaceutically active component of ginseng, is known to have anticancer and antitumor effects. However, white ginseng and red ginseng have extremely low concentrations of Rh2 or Rh2-Mix [20(S)-Rh2, 20(R)-Rh2, Rk2, and Rh3].
Muhammad Zubair Siddiqi, Chang-Hao Cui, Seul-Ki Park, Nam Soo Han, Sun-Chang Kim, Wan-Taek Im   +5 more
doaj   +1 more source

The Anti-Inflammatory Effect and Mucosal Barrier Protection of Clostridium butyricum RH2 in Ceftriaxone-Induced Intestinal Dysbacteriosis

Frontiers in Cellular and Infection Microbiology, 2021
This study aimed at determining the beneficial effect of Clostridium butyricum (CB) RH2 on ceftriaxone-induced dysbacteriosis. To this purpose, BALB/c mice were exposed to ceftriaxone (400 mg/ml) or not (control) for 7 days, and administered a daily oral
Yuyuan Li, Man Liu, He Liu, Xue Sui, Yinhui Liu, Xiaoqing Wei, Chunzheng Liu, Yiqin Cheng, Weikang Ye, Binbin Gao, Xin Wang, Qiao Lu, Hao Cheng, Lu Zhang, Jieli Yuan, Ming Li   +15 more
doaj   +1 more source

Ginsenoside Rh2 represses autophagy to promote cervical cancer cell apoptosis during starvation

Chinese Medicine, 2020
Background Cancer cells through autophagy-mediated recycling to meet the metabolic demands of growth and proliferation. The steroidal saponin 20(S)-ginsenoside Rh2 effectively inhibits the growth and survival of a variety of tumor cell lines and animal ...
Jiawen Wang, Shuai Bian, Siming Wang, Song Yang, Wanying Zhang, Daqing Zhao, Meichen Liu, Xueyuan Bai   +7 more
doaj   +1 more source