Results 131 to 140 of about 191,346 (272)

Translational Remodeling of the Synaptic Proteome During Aging

open access: yesAging Cell, EarlyView.
Aging induces a decoupling of protein regulation between the soma and the synapse. In particular, transcripts coding for ribosomal proteins decrease and their corresponding proteins increase in the synapse while the opposite happens in the soma. At the same time, synapse‐specific regulation of splicing takes place.
Cinzia Caterino   +10 more
wiley   +1 more source

Rho GTPases and their effector proteins.

open access: yesBiochemical Journal, 2000
Anne L. Bishop, A. Hall
semanticscholar   +1 more source

Skin Lipid–Microbe Interplay Links Staphylococcus hominis to Barrier Control in Adult Atopic Dermatitis

open access: yesAllergy, EarlyView.
This study investigates mutual interaction of skin microbes and surface lipids in AD using the advanced method of shotgun lipidomics with ultra‐broad coverage of lipids and 16S amplicon sequencing of tape strips taken from lesional and non‐lesional AD and healthy controls.
Madhumita Bhattacharyya   +14 more
wiley   +1 more source

Proteomic profiling of porcine seminal extracellular vesicles reveals potential in vivo fertility biomarkers

open access: yesAndrology, EarlyView.
Abstract Background Predicting male fertility in farm animals remains a challenge. Seminal plasma (SP) contains a high amount of heterogeneous seminal extracellular vesicles (sEVs), believed involved in reproductive processes and maybe key to understanding male fertility.
Isabel Barranco   +6 more
wiley   +1 more source

Dysmorphic neurons express markers of inhibitory glycinergic signaling in focal cortical dysplasia IIb

open access: yesBrain Pathology, EarlyView.
Deep learning tissue mapping can guide region of interest selection for spatial transcriptomic analyses. Using this method, a transcriptional catalogue of focal cortical dysplasia type IIb was generated, revealing enrichment for markers of inhibitory glycinergic signaling in cytomegalic dysmorphic neurons.
Ameesha Paliwal   +8 more
wiley   +1 more source

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