Clearing Amyloid-Beta by Astrocytes: The Role of Rho GTPases Signaling Pathways as Potential Therapeutic Targets. [PDF]
Park G, Jin Z, Lu H, Du J.
europepmc +1 more source
Rho GTPases in the Amygdala-A Switch for Fears? [PDF]
Sarowar T, Grabrucker AM.
europepmc +1 more source
ABSTRACT Platelet shortages and limited storage stability restrict global platelet transfusion capacity, highlighting the need for efficient in vitro platelet production systems. This study establishes a simple, non‐genetic and cost‐effective system for efficient in vitro platelet‐like particle (PLP) production from human hematopoietic stem/progenitor ...
Nittaya Jiamvoraphong +8 more
wiley +1 more source
Interaction Between Actin and Microtubules During Plant Development
ABSTRACT The dynamic interaction between actin filaments (AFs) and microtubules (MTs) plays a crucial role in regulating key developmental and physiological processes in plant cells, particularly in the formation of specialized cell types with distinct shapes and functions, such as pollen tubes, trichomes, and leaf epidermal cells.
Zining Wu +3 more
wiley +1 more source
Depletion of the Rho GTPases Cdc42, Rac1 or RhoA reduces PDGF-induced STAT1 and STAT3 signaling. [PDF]
Wåhlén E, Lennartsson J, Heldin J.
europepmc +1 more source
Emerging roles for Rho GTPases operating at the Golgi complex. [PDF]
Mysior MM, Simpson JC.
europepmc +1 more source
ABSTRACT Of the three types of cytoskeleton known in animals—actin, microtubules, and intermediate filaments—only actin and microtubules exist in plants. Both play important roles in cellular shaping, organelle movement, organization of the endomembrane system, and cell signaling.
Norman R. Groves +3 more
wiley +1 more source
Functionally redundant Rho GTPases Cdc42 and RacA regulate aflatoxin synthesis and pathogenicity in <i>Aspergillus flavus</i> by controlling morphogenesis, oxidative balance and energy metabolism. [PDF]
Xu J, Ren J, Zhang Y, Han Z, Kong Q.
europepmc +1 more source
Cross-talk-dependent cortical patterning of Rho GTPases during cell repair. [PDF]
Moe A +6 more
europepmc +1 more source
Aspartame Increases the Risk of Pancreatic Ductal Adenocarcinoma
Aspartame (APM) is a widely used artificial sweetener associated with various health concerns, including potential links to diabetes, cardiovascular diseases, and an increased risk of cancer. A comprehensive approach incorporating data mining, machine learning, network toxicology, molecular docking, molecular dynamics simulations, and clinical sample ...
Jumin Xie +5 more
wiley +1 more source

