Results 201 to 210 of about 72,889 (250)
Astrocyte Senescence Impairs Synaptogenesis due to Thrombospondin‐1 Loss
Senescent hippocampal astrocytes lose TSP secretion, impairing excitatory synaptogenesis via the α2δ‐1 pathway. Restoring TSP‐1 rescues synaptic formation, revealing the contribution of astrocyte senescence to age‐related hippocampal synaptic decline.
Stefano Ercoli +3 more
wiley +1 more source
Rho GTPases Signaling in Zebrafish Development and Disease. [PDF]
Boueid MJ +4 more
europepmc +1 more source
MMP-9 Signaling Pathways That Engage Rho GTPases in Brain Plasticity. [PDF]
Figiel I +6 more
europepmc +1 more source
This study investigates mutual interaction of skin microbes and surface lipids in AD using the advanced method of shotgun lipidomics with ultra‐broad coverage of lipids and 16S amplicon sequencing of tape strips taken from lesional and non‐lesional AD and healthy controls.
Madhumita Bhattacharyya +14 more
wiley +1 more source
STK25 and MST3 Have Overlapping Roles to Regulate Rho GTPases during Cortical Development. [PDF]
Matsuki T +5 more
europepmc +1 more source
Abstract Background Predicting male fertility in farm animals remains a challenge. Seminal plasma (SP) contains a high amount of heterogeneous seminal extracellular vesicles (sEVs), believed involved in reproductive processes and maybe key to understanding male fertility.
Isabel Barranco +6 more
wiley +1 more source
Abstract Epicardial adipose tissue (EAT) is a metabolically active visceral fat depot located between the myocardium and the visceral pericardium, exerting direct paracrine and vasocrine effects on the heart and coronary vessels. Under physiological conditions, EAT supports myocardial energy metabolism and thermoregulation through fatty acid supply and
Elisabeth Heuboeck +2 more
wiley +1 more source
Dysregulation of Rho GTPases in Human Cancers. [PDF]
Jung H, Yoon SR, Lim J, Cho HJ, Lee HG.
europepmc +1 more source
The INF2 WH2/DAD domain, composed of hydrophobic and basic regions, forms a single α‐helix in solution. The hydrophobic segment is essential for INF2 function, as its deletion disrupts actin dynamics and causes nuclear abnormalities, like those seen in pathogenic INF2 DID variants. In contrast, natural INF2 WH2/DAD variants found in patients with renal
Leticia Labat‐de‐Hoz +5 more
wiley +1 more source
Hormones Secretion and Rho GTPases in Neuroendocrine Tumors. [PDF]
Streit L +4 more
europepmc +1 more source

