Results 21 to 30 of about 68,847 (285)
Small, Volume 19, Issue 2, January 11, 2023., 2023 Fluidic force microscopy and atomic force microscopy are used to investigate the interaction of preosteoblast cells with patterned surfaces having different pillar heights. The results reveal differences in cell adhesion strength, settling state, cytoskeleton reorganization and local elastic modulus between the cells adhered on the two different ...
Livia Angeloni +6 more
wiley +1 more source
Journal of Asthma and Allergy, 2021 Mark F McCarty,1 James J DiNicolantonio,2 Aaron Lerner3 1Catalytic Longevity Foundation, San Diego, CA, USA; 2Department of Preventive Cardiology, Saint Luke’s Mid America Heart Institute, Kansas, MO, USA; 3Chaim Sheba Medical Center, The ...
McCarty MF, DiNicolantonio JJ, Lerner A
doaj
Rho GTPases and their downstream effectors in megakaryocyte biology
Platelets, 2019 Megakaryocytes differentiate from hematopoietic stem cells in the bone marrow. The transition of megakaryocytes to platelets is a complex process. Thereby, megakaryocytes extend proplatelets into sinusoidal blood vessels, where the proplatelets undergo ...
Irina Pleines +2 more
doaj +1 more source
RhoA Proteolysis Regulates the Actin Cytoskeleton in Response to Oxidative Stress. [PDF]
PLoS ONE, 2016 The small GTPase RhoA regulates the actin cytoskeleton to affect multiple cellular processes including endocytosis, migration and adhesion. RhoA activity is tightly regulated through several mechanisms including GDP/GTP cycling, phosphorylation ...
Marie-Pier Girouard +4 more
doaj +1 more source
RhoA as a Key Regulator of Innate and Adaptive Immunity
Cells, 2019 RhoA is a ubiquitously expressed cytoplasmic protein that belongs to the family of small GTPases. RhoA acts as a molecular switch that is activated in response to binding of chemokines, cytokines, and growth factors, and via mDia and the ROCK signaling ...
Matthias Bros +3 more
semanticscholar +1 more source
Phosphorylation and Activation of RhoA by ERK in Response to Epidermal Growth Factor Stimulation. [PDF]
PLoS ONE, 2016 The small GTPase RhoA has been implicated in various cellular activities, including the formation of stress fibers, cell motility, and cytokinesis. In addition to the canonical GTPase cycle, recent findings have suggested that phosphorylation further ...
Junfeng Tong +3 more
doaj +1 more source
RhoA promotes epidermal stem cell proliferation via PKN1-cyclin D1 signaling. [PDF]
PLoS ONE, 2017 OBJECTIVE:Epidermal stem cells (ESCs) play a critical role in wound healing, but the mechanism underlying ESC proliferation is not well defined. Here, we explore the effects of RhoA on ESC proliferation and the possible underlying mechanism.
Fan Wang +12 more
doaj +1 more source
Frontiers in Immunology, 2022 The generation, differentiation, survival and activation of B cells are coordinated by signals emerging from the B cell antigen receptor (BCR) or its precursor, the pre-BCR.
Anila Vadakumchery +22 more
doaj +1 more source
RhoA mediates epithelial cell shape changes via mechanosensitive endocytosis
bioRxiv, 2019 Morphogenetic movements require tight spatiotemporal control over cell-cell junction lengths. Contractile forces, acting at adherens junctions, alter cell-cell contact lengths in a cyclic fashion as a mechanical ratchet.
Kate E. Cavanaugh +4 more
semanticscholar +1 more source
Protein Kinase C-related Kinase and ROCK Are Required for Thrombin-induced Endothelial Cell Permeability Downstream from G{alpha}12/13 and G{alpha}11/q [PDF]
The Journal of Biological Chemistry 283, 44 (2008) 29888-96, 2008 Increase in vascular permeability occurs under many physiological conditions and is central in diverse human pathologies. Thrombin is a pro-coagulant serine protease, which causes the local loss of endothelial barrier integrity thereby enabling the rapid extravasation of plasma proteins and the local formation of fibrin-containing clots.
arxiv +1 more source