Results 31 to 40 of about 123,069 (394)
Mark F McCarty,1 James J DiNicolantonio,2 Aaron Lerner3 1Catalytic Longevity Foundation, San Diego, CA, USA; 2Department of Preventive Cardiology, Saint Luke’s Mid America Heart Institute, Kansas, MO, USA; 3Chaim Sheba Medical Center, The ...
McCarty MF, DiNicolantonio JJ, Lerner A
doaj
Kuo-Feng Hua,1,2,* Lan-Hui Li,3,* Hsin-Chiao Yu,4 Wei-Ting Wong,1 Hsien-Ta Hsu4,5 1Department of Biotechnology and Animal Science, National Ilan University, Yilan, 26047, Taiwan; 2Department of Medical Research, China Medical University Hospital,
Hua KF, Li LH, Yu HC, Wong WT, Hsu HT
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RhoA Proteolysis Regulates the Actin Cytoskeleton in Response to Oxidative Stress. [PDF]
The small GTPase RhoA regulates the actin cytoskeleton to affect multiple cellular processes including endocytosis, migration and adhesion. RhoA activity is tightly regulated through several mechanisms including GDP/GTP cycling, phosphorylation ...
Marie-Pier Girouard +4 more
doaj +1 more source
Aging-associated changes in microRNA expression profile of internal anal sphincter smooth muscle: Role of microRNA-133a. [PDF]
A comprehensive genomic and proteomic, computational, and physiological approach was employed to examine the (previously unexplored) role of microRNAs (miRNAs) as regulators of internal anal sphincter (IAS) smooth muscle contractile phenotype and basal ...
Addya, Sankar +6 more
core +3 more sources
Phosphorylation and Activation of RhoA by ERK in Response to Epidermal Growth Factor Stimulation. [PDF]
The small GTPase RhoA has been implicated in various cellular activities, including the formation of stress fibers, cell motility, and cytokinesis. In addition to the canonical GTPase cycle, recent findings have suggested that phosphorylation further ...
Junfeng Tong +3 more
doaj +1 more source
PECAM-1 engagement counteracts ICAM-1-induced signaling in brain vascular endothelial cells [PDF]
Interactions between leukocytes and vascular endothelial cells are mediated by a complex set of membrane adhesion molecules which transduce bi-directional signals in both cell types.
Adamson +53 more
core +2 more sources
RhoA/Rho‐kinases in asthma: from pathogenesis to therapeutic targets
Asthma is a chronic and heterogeneous disease characterised by airway inflammation and intermittent airway narrowing. The key obstacle in the prevention and treatment of asthma has been our incomplete understanding of its aetiology and biological ...
Yan Zhang +7 more
semanticscholar +1 more source
Rho GTPases and their downstream effectors in megakaryocyte biology
Megakaryocytes differentiate from hematopoietic stem cells in the bone marrow. The transition of megakaryocytes to platelets is a complex process. Thereby, megakaryocytes extend proplatelets into sinusoidal blood vessels, where the proplatelets undergo ...
Irina Pleines +2 more
doaj +1 more source
RhoA promotes epidermal stem cell proliferation via PKN1-cyclin D1 signaling. [PDF]
OBJECTIVE:Epidermal stem cells (ESCs) play a critical role in wound healing, but the mechanism underlying ESC proliferation is not well defined. Here, we explore the effects of RhoA on ESC proliferation and the possible underlying mechanism.
Fan Wang +12 more
doaj +1 more source
The generation, differentiation, survival and activation of B cells are coordinated by signals emerging from the B cell antigen receptor (BCR) or its precursor, the pre-BCR.
Anila Vadakumchery +22 more
doaj +1 more source

