Results 21 to 30 of about 5,406 (212)

RHOPTRY PROTEINS OF PLASMODIUM SPECIES

The Journal of Protozoology Research, 2000
Rhoptry proteins of Plasmodium sp. participate in host cell invasion and intracellular parasite development. In this review, the major rhoptry proteins of P.
TOBILI Y. SAM-YELLOWE, HISASHI FUJIOKA
openaire   +2 more sources

The Plasmodium falciparum rhoptry bulb protein RAMA plays an essential role in rhoptry neck morphogenesis and host red blood cell invasion. [PDF]

PLoS Pathogens, 2019
The malaria parasite Plasmodium falciparum invades, replicates within and destroys red blood cells in an asexual blood stage life cycle that is responsible for clinical disease and crucial for parasite propagation.
Emma S Sherling, Abigail J Perrin, Ellen Knuepfer, Matthew R G Russell, Lucy M Collinson, Louis H Miller, Michael J Blackman   +6 more
doaj   +2 more sources

Toxoplasma rhoptry proteins that affect encephalitis outcome

Cell Death Discovery, 2023
AbstractToxoplasma gondii, a widespread obligate intracellular parasite, can infect almost all warm-blooded animals, including humans. The cellular barrier of the central nervous system (CNS) is generally able to protect the brain parenchyma from infectious damage. However, T.
Xinlei Wang, Lai Qu, Jie Chen, Yufen Jin, Kaisong Hu, Zhengjie Zhou, Jiaqi Zhang, Yiming An, Jingtong Zheng   +8 more
openaire   +4 more sources

Plasmodium falciparum Rab1A Localizes to Rhoptries in Schizonts. [PDF]

PLoS ONE, 2016
Over-expression of a GFP-PfRab1A fusion protein in Plasmodium falciparum schizonts produces a punctate pattern of fluorescence typical of rhoptries, secretory organelles involved in host cell invasion.
David Morse, Wesley Webster, Ming Kalanon, Gordon Langsley, Geoffrey I McFadden   +4 more
doaj   +6 more sources

Identification of three novel Toxoplasma gondii rhoptry proteins [PDF]

International Journal for Parasitology, 2014
The rhoptries are key secretory organelles from apicomplexan parasites that contain proteins involved in invasion and modulation of the host cell. Some rhoptry proteins are restricted to the posterior bulb (ROPs) and others to the anterior neck (RONs).
McFetridge, Kiva, Camejo, Ana, Gold, Daniel A., Lu, Diana, Julien, Lindsay, Yang, Ninghan, Saeij, Jeroen, Jensen, Kirk D.   +7 more
openaire   +7 more sources

The Plasmodium vivax rhoptry-associated protein 1

Biochemical and Biophysical Research Communications, 2006
Rhoptries are cellular organelles localized at the apical pole of apicomplexan parasites. Their content is rich in lipids and proteins that are released during target cell invasion. Plasmodium falciparum rhoptry-associated protein 1 (RAP1) has been the most widely studied among this parasite species' rhoptry proteins and is considered to be a good anti-
Oscar, Perez-Leal, Alvaro, Mongui, Jimena, Cortes, Gloria, Yepes, Jesus, Leiton, Manuel A, Patarroyo   +5 more
openaire   +3 more sources

Rhoptry proteins affect the placental barrier in the context of Toxoplasma gondii infection: Signaling pathways and functions

Ecotoxicology and Environmental Safety
Toxoplasma gondii is an opportunistic and pathogenic obligate intracellular parasitic protozoan that is widespread worldwide and can infect most warm-blooded animals, seriously endangering human health and affecting livestock production.
Xinlei Wang, Lai Qu, Jie Chen, Kaisong Hu, Zhengjie Zhou, Jiaqi Zhang, Yiming An, Jingtong Zheng   +7 more
doaj   +2 more sources

Evidence that the Plasmodium falciparum Protein Sortilin Potentially Acts as an Escorter for the Trafficking of the Rhoptry-Associated Membrane Antigen to the Rhoptries

mSphere, 2018
The rhoptry organelle is critical for the invasion of an erythrocyte by the malaria parasite Plasmodium falciparum. Despite their critical roles, the mechanisms behind their biogenesis are still poorly defined.
Stéphanie Hallée, Justin A. Boddey, Alan F. Cowman, Dave Richard   +3 more
doaj   +2 more sources

PvRON2, a new Plasmodium vivax rhoptry neck antigen [PDF]

Malaria Journal, 2011
Background Rhoptries are specialized organelles from parasites belonging to the phylum Apicomplexa; they secrete their protein content during invasion of host target cells and are sorted into discrete subcompartments within rhoptry neck or bulb.
Curtidor Hernando, Arévalo-Pinzón Gabriela, Patiño Liliana C, Patarroyo Manuel A   +3 more
doaj   +4 more sources

Therapeutic Antitoxoplasmosis Potential of <i>Garcinia cambogia</i>: Evidence From In Silico and In Vivo Studies. [PDF]

J Trop Med
Toxoplasma gondii, an opportunistic protozoan, is widely prevalent and poses potential health risks. Its treatment remains challenging with several side effects, urging the exploration of new, safe, and efficient drugs. We aimed to explore the therapeutic efficacy of the medicinal plant Garcinia cambogia (GC) against both acute and chronic ...
Ghallab MMI, El-Wakil ES, Zalat RS, Almayouf MA, Al-Rashidi HS, Al-Megrin WAI, Morsy SM.   +6 more
europepmc   +2 more sources