Results 31 to 40 of about 5,406 (212)
Overexpression of Eimeria tenella Rhoptry Kinase 2 Induces Early Production of Schizonts
Microbiology Spectrum, 2023 Eimeria tenella is an obligate intracellular parasite responsible for avian coccidiosis. Like other apicomplexan parasites, such as Toxoplasma gondii, cell invasion and intracellular development rely on apical organelle content discharge, named ...
Adeline Ribeiro E. Silva +8 more
doaj +1 more source
mSphere, 2020 In the Plasmodium life cycle, two infectious stages of parasites, merozoites and sporozoites, share rhoptry and microneme apical structures. A crucial step during merozoite invasion of erythrocytes is the discharge to the host cell membrane of some ...
Mamoru Nozaki +5 more
doaj +3 more sources
Identification of a Novel RAMA/RON3 Rhoptry Protein Complex in Plasmodium falciparum Merozoites
Frontiers in Cellular and Infection Microbiology, 2021 Malaria causes a half a million deaths annually. The parasite intraerythrocytic lifecycle in the human bloodstream is the major cause of morbidity and mortality. Apical organelles of merozoite stage parasites are involved in the invasion of erythrocytes.
Daisuke Ito +9 more
doaj +1 more source
Rhoptries: an arsenal of secreted virulence factors [PDF]
Current Opinion in Microbiology, 2007 Apicomplexan parasites use actin-based motility coupled with regulated protein secretion from apical organelles to actively invade host cells. Crucial in this process are rhoptries, club-shaped secretory organelles that discharge their contents during parasite invasion into host cells.
Peter J, Bradley, L David, Sibley
openaire +2 more sources
Proteome Analysis of Rhoptry-Enriched Fractions Isolated from Plasmodium Merozoites
, 2016 The rhoptries of Plasmodium species participate in merozoite invasion and modification of the host erythrocyte. However, only a few rhoptry proteins have been identified using conventional gene identification protocols.
Tobili Y. Sam-Yellowe (2705884) +6 more
core +3 more sources
Frontiers in Cellular and Infection Microbiology, 2021 The severity of toxoplasmosis depends on a combination of host and parasite factors. Among them, the Toxoplasma strain causing the infection is an important determinant of the disease outcome.
David Arranz-Solís +5 more
doaj +1 more source
Expression and Localization Profiles of Rhoptry Proteins in Plasmodium berghei Sporozoites
Frontiers in Cellular and Infection Microbiology, 2019 In the Plasmodium lifecycle two infectious stages of parasites, merozoites, and sporozoites, efficiently infect mammalian host cells, erythrocytes, and hepatocytes, respectively.
Naohito Tokunaga +7 more
doaj +1 more source
The strategies of NLRP3 inflammasome to combat Toxoplasma gondii
Frontiers in Immunology, 2022 Infection with the protozoan parasite Toxoplasma gondii (T. gondii) results in the activation of nucleotide-binding domain leucine-rich repeat containing receptors (NLRs), which in turn leads to inflammasome assembly and the subsequent activation of ...
Chanjin Yoon +4 more
doaj +1 more source
Frontiers in Immunology, 2019 Toxoplasma gondii secretes rhoptry (ROP) and dense granule (GRA) effector proteins to evade host immune clearance mediated by interferon gamma (IFN-γ), immunity-related GTPase (IRG) effectors, and CD8+ T cells.
Leah M. Rommereim +6 more
doaj +1 more source
mSphere, 2023 During invasion, Plasmodium parasites secrete proteins from rhoptry and microneme apical end organelles, which have crucial roles in attaching to and invading target cells.
Minami Baba +5 more
doaj +1 more source