Results 111 to 120 of about 168,078 (169)

Ribo-Tag.

, 2019
(A) Overview of the procedure. Tissue homogenate, following removal of nuclei and cell debris (S1 supernatant), is split into fractions for purifying specific classes of nucleic acids.
Lech Kaczmarczyk (587512), Ashish Rajput (269079), Stefan Bonn (2619949), Joachim Degen (214705), Vikas Bansal (79044), Walker Scot Jackson (7164908), Raza-ur Rahman (7164899), Wiesław Krzyżak (7164902), Stefanie Poll (7164905), Martin Fuhrmann (237245)   +9 more
core   +1 more source

Transcriptome and translatome comparison of tissues from Arabidopsis thaliana

Scientific Data
Translation is one of the multiple complementary steps that orchestrates gene activity. In contrast to the straightforwardness of transcriptional surveys, genome-wide profiles of the translational landscape of plant cells remain technically challenging ...
Isabel Cristina Vélez-Bermúdez, Wen-Dar Lin, Shu-Jen Chou, Ai-Ping Chen, Wolfgang Schmidt   +4 more
doaj   +1 more source

uORF-Tools-Workflow for the determination of translation-regulatory upstream open reading frames.

PLoS ONE, 2019
Ribosome profiling (ribo-seq) provides a means to analyze active translation by determining ribosome occupancy in a transcriptome-wide manner. The vast majority of ribosome protected fragments (RPFs) resides within the protein-coding sequence of mRNAs ...
Anica Scholz, Florian Eggenhofer, Rick Gelhausen, Björn Grüning, Kathi Zarnack, Bernhard Brüne, Rolf Backofen, Tobias Schmid   +7 more
doaj   +1 more source

Livestock Multi‐Omics Integration: A Systematic Framework From Statistical Association to Causal Interpretation

Advanced Science, Volume 13, Issue 50, 7 September 2026.
A three‐tier livestock multi‐omics framework resolves four typical analytical pitfalls. Moving from statistical association through machine learning preprocessing to triple‐modal causal inference, it converts omics results into genomic selection and gene editing strategies to achieve One Health, underpinned by multi‐omics data, multimodal sequencing ...
Jiying Wen, Zhongyu Wang, Jieping Huang, Fen Li, Ningbo Chen, Yun Ma   +5 more
wiley   +1 more source

Detecting differential usage of exons from RNA-Seq data [PDF]

, 2012
RNA-Seq is a powerful tool for the study of alternative splicing and other forms of alternative isoform expression. Understanding the regulation of these processes requires comparisons between treatments, tissues or conditions.
Simon Anders, Wolfgang Huber, Alejandro Reyes   +2 more
core   +1 more source

CPT1A through succinylation regulates the CTCF/LINC01503‒91aa feedback loop to promote gemcitabine resistance in pancreatic ductal adenocarcinoma

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
LINC01503 encoded a 91‐amino acid protein named 1503‒91aa, which enhanced carnitine palmitoyl transferase 1A (CPT1A) activity and regulated fatty acid oxidation (FAO) by competitively binding to malonyl‐CoA. Meanwhile, we found a positive feedback loop whereby CPT1A acts as a succinyltransferase to stabilise CTCF (a transcription factor driving ...
De‐Liang Fang, Si‐Yuan Lu, Zhi‐De Liu, Qiong‐Cong Xu, Yang‐Yinhui Yu, Ying‐Qin Zhu, Ming‐Jian Ma, Jing‐Yuan Ye, Xiao‐Yu Yin   +8 more
wiley   +1 more source

PRI-CAT: a web-tool for the analysis, storage and visualization of plant ChIP-seq experiments. [PDF]

, 2011
Although several tools for the analysis of ChIP-seq data have been published recently, there is a growing demand, in particular in the plant research community, for computational resources with which such data can be processed, analyzed, stored ...
Muino, J.M., Marlous Hoogstraat, Dijk, A.D.J., van, Roeland C. H. J. van Ham, Ham, R.C.H.J., van, van Dijk, A.D.J., van Ham, R.C.H.J., Jose M. Muiño, Aalt D. J. van Dijk, Hoogstraat, M.   +9 more
core   +1 more source

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

Equine Veterinary Journal, Volume 58, Issue 5, Page 1413-1444, September 2026.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska, Jowita Grzędzicka‐Agko, Paula Kiełbik, Michał Trela, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

METTL14 Ameliorates Mitochondrial Dysfunction and Autophagy in Lens Epithelial Cells of Diabetic Cataracts via m6A Modification of RPL3

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 9, September 2026.
ABSTRACT Diabetic cataracts are a leading cause of blindness, with lens epithelial cells (LECs) exhibiting mitochondrial dysfunction and autophagy inhibition under high glucose (HG) conditions. Methyltransferase‐like 14 (METTL14), an RNA methyltransferase, regulates N6‐methyladenosine (m6A) RNA modification; however, its role in modulating ...
Rui Li, Xue Wang, Wei Du, Qian Li, Hong‐Ping Cui   +4 more
wiley   +1 more source

Ribo-seQC: comprehensive analysis of cytoplasmic and organellar ribosome profiling data [PDF]

, 2019
Summary: Ribosome profiling enables genome-wide analysis of translation with unprecedented resolution. We present Ribo-seQC, a versatile tool for the comprehensive analysis of Ribo-seq data, providing in-depth insights on data quality and translational ...
Ohler, U., Harnett, D., Calviello, L., Sydow, D.   +3 more
core   +1 more source