Results 191 to 200 of about 25,036 (270)

Characterization of Bromelain‐Soluble Sheepskin (Ovis aries) Proteins and Effect of In Vitro Gastrointestinal Digestion on Angiotensin Converting Enzyme Inhibition Activity

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Novel bioactive peptides resulted from in vitro gastrointestinal digestion of soluble sheep skin protein. ABSTRACT This work characterizes proteins extracted from sheepskin using bromelain and examines angiotensin converting enzyme (ACE) inhibition activity of the peptides generated by in vitro gastrointestinal digestion (GID).
Dita Prameswari Trenggono Putri, Marta Gallego, Mohammad Zainal Abidin, Nanung Agus Fitriyanto, Leticia Mora, Fidel Toldrá, Yuny Erwanto   +6 more
wiley   +1 more source

The U1 snRNP-specific protein U1C is a key regulator of SMN complex-mediated snRNP formation. [PDF]

J Biol Chem
Ngu DM, Myti S, Khan AA, Keita J, Moore T, Andega P, Aziz A, Raj R, Johnson-Winters K, Suh EH, So BR.   +10 more
europepmc   +1 more source

EIF4A3‐Induced Circular RNA circSnd1 Promotes Muscle Atrophy and Muscle Ageing by Stabilizing EEF1A1

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Muscle atrophy is a common complication of ageing, and many chronic conditions, lacks defined therapeutic interventions. It is still mostly unknown how circular RNAs contribute to muscle atrophy. Methods circRNA sequencing and quantitative real‐time PCR were performed to detect the changed circRNAs in muscle atrophy models and aged ...
Jin Li, Bing Jin, Yuwei Yan, Yuying Chen, Xiaohang Yin, Xinyi Ren, Qian Li, Jingying Chen, Siqi Wang, Tingting Yang, Yanan Zhang, Qiumeng Nie, Dongchao Lu, Ming Wu, Yan Yu, Lei Chen, Tarun Keswani, Guoping Li, Dragos Cretoiu, T. Scott Bowen, Junjie Xiao, Yongjun Zheng   +21 more
wiley   +1 more source

Identification of Fibrillarin and Cajal Bodies Under DNA Replication Stress Conditions in Root Meristem Cells of <i>Allium cepa</i>. [PDF]

Int J Mol Sci
Żabka A, Gocek-Szczurtek N, Wróblewski M, Polit JT.   +3 more
europepmc   +1 more source

The Secretome of Human Trophoblast Stem Cells Attenuates Senescence‐Associated Traits

Aging Cell, Volume 25, Issue 2, February 2026.
Human trophoblast stem cell‐derived secretome/conditioned medium (hTSC‐CM) and the extracellular vesicles (EVs) therein suppress DNA damage and NF‐κB activation in senescent fibroblasts, in turn reducing the production of senescence‐associated secretory phenotype (SASP) factors. This study highlights hTSC‐CM and EVs as potential senotherapeutic agents.
Kotb Abdelmohsen, Jennifer L. Martindale, Martina Rossi, Chang Hoon Shin, Apala Pal, Rachel Munk, Martin Salamini‐Montemurri, Mirko Baranzini, Ethan M. Arends, Maja Mustapic, Yuta Lee, Jau‐Nan Lee, Sicco H. Popma, Justin Hu, Nathan Duda, Carlos J. Nogueras‐Ortiz, Dimitrios Kapogiannis, Chang‐Yi Cui, Myriam Gorospe   +18 more
wiley   +1 more source

Splice it hot: How nuclear PP2A B'η regulates splicing fidelity by targeting the heat-stressed spliceosome. [PDF]

Plant Cell
Wang J.
europepmc   +1 more source

MSC‐Derived Exosomal lnc‐AGT‐3: A Novel Anti‐Angiogenic Target in Age‐Related Macular Degeneration Through p53 Signaling Pathway

Aging Cell, Volume 25, Issue 2, February 2026.
MSC‐derived exosomes deliver lnc‐AGT‐3 to vascular endothelial cells, where it binds hnRNP K in the nucleus. This interaction inhibits p53 ubiquitination, enhancing p53 stabilization and transcriptional activation of anti‐angiogenic targets TSP1. Consequently, p53‐mediated signaling is potentiated, effectively suppressing choroidal neovascularization ...
Lingjie Kong, Xiaoyan Han, Siyi Qi, Duo Li, Jingyue Zhang, Linyu Zhang, Shujie Zhang, Qin Jiang, Biao Yan, Chen Zhao   +9 more
wiley   +1 more source

Exploring the role and therapeutic potential of RNA N6-methyladenosine modification in abortion disease pathology: a comprehensive review. [PDF]

Front Genet
Chang Z, Li LH, Lv LZ, Wang ZD, Wang QY, Zhu H, Jiang B, Zhou XM, Han YP, Pan X, Ren L, Cheng S, Lei ZM.   +12 more
europepmc   +1 more source

U11/U12 Small Nuclear Ribonucleoprotein 25 kDa Protein [PDF]

, 2020
openaire   +1 more source

Targeting Overexpressed IDO in Stromal Cells as a Potential Therapeutic Strategy in Multiple Myeloma

Cancer Science, Volume 117, Issue 2, Page 325-334, February 2026.
IDO expression in stromal cells was upregulated by MM cells via the JAK–STAT1–NF‐κB–IRF1 signaling pathway. JAK inhibitor abolished IDO and IRF1 upregulation. ABSTRACT Stromal cells are an essential component of the tumor microenvironment (TME) in multiple myeloma (MM). Indoleamine 2,3‐dioxygenase 1 (IDO), an enzyme that metabolizes tryptophan (Trp) to
Toru Ebina, Masaki Ri, Yoshiaki Marumo, Tomoyuki Nakamura, Hirokazu Sasaki, Yoshiko Oshima, Takahiro Nakashima, Shinya Hagiwara, Arisa Asano, Shiori Kinoshita, Tomotaka Suzuki, Tomoko Narita, Ayako Masaki, Takaomi Sanda, Kazufumi Yamagata, Kohmei Kubo, Hirokazu Komatsu, Hirotake Sakuraba, Shinsuke Iida   +18 more
wiley   +1 more source