Results 31 to 40 of about 15,077 (245)
Life, 2023 Pre-mRNA splicing is a process used by eukaryotic cells to generate messenger RNAs that can be translated into proteins. During splicing, the non-coding regions of the RNAs (introns) are removed from pre-mRNAs and the coding regions (exons) are joined ...
Miroslava Kretova +3 more
doaj +1 more source
Cytoplasmic Assembly and Nuclear Accumulation of Mature Small Nuclear Ribonucleoprotein Particles
Journal of Biological Chemistry, 1989 The assembly pathway of small nuclear ribonucleoprotein (snRNP) particles in the cytoplasm of L929 mouse fibroblasts was analyzed by observing the nuclear accumulation of snRNP proteins. Immunoprecipitations of nuclear and cytoplasmic fractions after a pulse label and chase indicate that the snRNP D, E, F, and G proteins assemble first, followed by the
R J, Feeney +3 more
openaire +2 more sources
The sphere organelle contains small nuclear ribonucleoproteins. [PDF]
Proceedings of the National Academy of Sciences, 1989 We show by immunofluorescence microscopy of amphibian oocyte nuclei that small nuclear ribonucleoproteins (snRNPs) occur in lampbrush chromosome loops, in a few dozen extrachromosomal organelles previously described as "spheres," and in thousands of smaller granules.
J G, Gall, H G, Callan
openaire +2 more sources
Gemin5: A Multitasking RNA-Binding Protein Involved in Translation Control
Biomolecules, 2015 Gemin5 is a RNA-binding protein (RBP) that was first identified as a peripheral component of the survival of motor neurons (SMN) complex. This predominantly cytoplasmic protein recognises the small nuclear RNAs (snRNAs) through its WD repeat domains ...
David Piñeiro +3 more
doaj +1 more source
Biology Open, 2018 Small Cajal body-specific RNAs (scaRNAs) are part of small Cajal body-specific ribonucleoproteins (scaRNPs) that modify small nuclear RNA (snRNA) in Cajal bodies (CBs).
Madelyn K. Logan +2 more
doaj +1 more source
Polypeptide components ofDrosophilasmall nuclear ribonucleoprotein particles
Nucleic Acids Research, 1991 In eukaryotes splicing of pre-mRNAs is mediated by the spliceosome, a dynamic complex of small nuclear ribonucleoprotein particles (snRNPs) that associate transiently during spliceosome assembly and the splicing reaction. We have purified snRNPs from nuclear extracts of Drosophila cells by affinity chromatography with an antibody specific for the ...
PATERSON, T +4 more
openaire +4 more sources
Biology Open, 2017 Many ribonucleoproteins (RNPs), which are comprised of noncoding RNA and associated proteins, are involved in essential cellular processes such as translation and pre-mRNA splicing.
Aaron R. Poole +4 more
doaj +1 more source
Coilin Can Form a Complex with the U7 Small Nuclear Ribonucleoprotein [PDF]
Molecular Biology of the Cell, 1998 Coiled bodies (CBs) in the amphibian oocyte nucleus are spherical structures up to 10 μm or more in diameter, much larger than their somatic counterparts, which rarely exceed 1 μm. Oocyte CBs may have smaller granules attached to their surface or embedded within them, which are identical in structure and composition to the many hundreds of B ...
M, Bellini, J G, Gall
openaire +2 more sources
Cell ReportsSummary: Membrane-less subcellular compartments play important roles in various cellular functions. Although techniques exist to identify components of cellular bodies, a comprehensive method for analyzing both static and dynamic states has not been ...
Keisuke Noguchi +17 more
doaj +1 more source
Structure and conformational plasticity of the U6 small nuclear ribonucleoprotein core [PDF]
Acta Crystallographica Section D Structural Biology, 2017 U6 small nuclear RNA (snRNA) is a key component of the active site of the spliceosome, a large ribonucleoprotein complex that catalyzes the splicing of precursor messenger RNA. Prior to its incorporation into the spliceosome, U6 is bound by the protein Prp24, which facilitates unwinding of the U6 internal stem-loop (ISL) so that it can pair with U4 ...
Eric J. Montemayor +5 more
openaire +2 more sources