Results 21 to 30 of about 24,694 (278)
Small nuclear ribonucleoprotein complexes of Drosophila melanogaster. [PDF]
Proceedings of the National Academy of Sciences, 1982 We report here on the isolation and characterization of small nuclear ribonucleoproteins (snRNPs) and corresponding small nuclear RNA (snRNA) species from nuclei of Drosophila melanogaster. Velocity sedimentation in sucrose gradients was used to partially fractionate the RNPs; analysis of fractions so obtained suggests that, in general, one snRNP ...
J C, Wooley +3 more
openaire +2 more sources
PRP4: a protein of the yeast U4/U6 small nuclear ribonucleoprotein particle [PDF]
, 1989 The Saccharomyces cerevisiae prp mutants (prp2 through prp11) are known to be defective in pre-mRNA splicing at nonpermissive temperatures. We have sequenced the PRP4 gene and shown that it encodes a 52-kilodalton protein.
Abelson, John N., Banroques, Josette
core +1 more source
Small Nuclear Ribonucleoprotein Remodeling During Catalytic Activation of the Spliceosome [PDF]
Science, 2002 Major structural changes occur in the spliceosome during its activation just before catalyzing the splicing of pre–messenger RNAs (pre-mRNAs). Whereas changes in small nuclear RNA (snRNA) conformation are well documented, little is known about remodeling of small nuclear ribonucleoprotein (snRNP) structures during spliceosome ...
Makarov, E.M. +6 more
openaire +4 more sources
Plant snRNP Biogenesis: A Perspective from the Nucleolus and Cajal Bodies
Frontiers in Plant Science, 2018 Small nuclear ribonucleoproteins (snRNPs) are protein–RNA complexes composed of specific snRNP-associated proteins along with small nuclear RNAs (snRNAs), which are non-coding RNA molecules abundant in the nucleus.
Misato Ohtani, Misato Ohtani
doaj +1 more source
Rpl13a small nucleolar RNAs regulate systemic glucose metabolism [PDF]
, 2016 Small nucleolar RNAs (snoRNAs) are non-coding RNAs that form ribonucleoproteins to guide covalent modifications of ribosomal and small nuclear RNAs in the nucleus. Recent studies have also uncovered additional non-canonical roles for snoRNAs.
Alexis N. Harris +23 more
core +2 more sources
Targeted mutagenesis using CRISPR-Cas9 in the chelicerate herbivore Tetranychus urticae [PDF]
, 2020 The use of CRISPR-Cas9 has revolutionized functional genetic work in many organisms, including more and more insect species. However, successful gene editing or genetic transformation has not yet been reported for chelicerates, the second largest group ...
Dermauw, Wannes +5 more
core +1 more source
Polypeptide components of human small nuclear ribonucleoproteins. [PDF]
Proceedings of the National Academy of Sciences, 1983 Small nuclear RNA molecules (snRNAs) are associated with polypeptides in vivo, forming small nuclear ribonucleoprotein complexes (snRNPs). These snRNP complexes are targets for certain autoimmune antisera. Antisera of the type anti-Sm precipitate (and therefore define) a class including U1, U2, U4, U5, and U6 snRNAs, whereas antisera of the anti-RNP ...
J C, Wooley, L R, Zukerberg, S Y, Chung
openaire +2 more sources
Molecular determinants that govern scaRNA processing by Drosha/DGCR8
Biology Open, 2020 The Cajal body (CB) is a subnuclear domain that participates in the biogenesis of many different types of ribonucleoproteins (RNPs), including small nuclear RNPs (snRNPs), small Cajal body-specific RNPs (scaRNPs) and telomerase.
Douglas M. McLaurin +3 more
doaj +1 more source
Brazilian Journal of Medical and Biological Research, 2004 We detected anti-human small nuclear ribonucleoprotein (snRNP) autoantibodies in chagasic patients by different immunological methods using HeLa snRNPs.
M.C. Bosetto +3 more
doaj +1 more source
RNA-Seq analysis of splicing in Plasmodium falciparum uncovers new splice junctions, alternative splicing and splicing of antisense transcripts. [PDF]
, 2011 Over 50% of genes in Plasmodium falciparum, the deadliest human malaria parasite, contain predicted introns, yet experimental characterization of splicing in this organism remains incomplete.
DeRisi, Joseph L +2 more
core +3 more sources