Results 51 to 60 of about 139,231 (236)
Polypeptide components ofDrosophilasmall nuclear ribonucleoprotein particles
Nucleic Acids Research, 1991 In eukaryotes splicing of pre-mRNAs is mediated by the spliceosome, a dynamic complex of small nuclear ribonucleoprotein particles (snRNPs) that associate transiently during spliceosome assembly and the splicing reaction. We have purified snRNPs from nuclear extracts of Drosophila cells by affinity chromatography with an antibody specific for the ...
PATERSON, T +4 more
openaire +5 more sources
Gemin5: A Multitasking RNA-Binding Protein Involved in Translation Control
Biomolecules, 2015 Gemin5 is a RNA-binding protein (RBP) that was first identified as a peripheral component of the survival of motor neurons (SMN) complex. This predominantly cytoplasmic protein recognises the small nuclear RNAs (snRNAs) through its WD repeat domains ...
David Piñeiro +3 more
doaj +1 more source
Cellular bases of the RNA metabolism dysfunction in motor neurons of a murine model of spinal muscular atrophy: Role of Cajal bodies and the nucleolus [PDF]
, 2017 Spinal muscular atrophy (SMA) is caused by a homozygous deletion or mutation in the survival motor neuron 1 (SMN1) gene that leads to reduced levels of SMN protein resulting in degeneration of motor neurons (MNs).
Berciano, Maria T. +7 more
core +2 more sources
RNA-Seq analysis of splicing in Plasmodium falciparum uncovers new splice junctions, alternative splicing and splicing of antisense transcripts. [PDF]
, 2011 Over 50% of genes in Plasmodium falciparum, the deadliest human malaria parasite, contain predicted introns, yet experimental characterization of splicing in this organism remains incomplete.
DeRisi, Joseph L +2 more
core +3 more sources
Biology Open, 2018 Small Cajal body-specific RNAs (scaRNAs) are part of small Cajal body-specific ribonucleoproteins (scaRNPs) that modify small nuclear RNA (snRNA) in Cajal bodies (CBs).
Madelyn K. Logan +2 more
doaj +1 more source
Conserved requirement for DEAD-box RNA helicase Gemin3 in Drosophila oogenesis [PDF]
, 2012 Background: DEAD-box RNA helicase Gemin3 is an essential protein since its deficiency is lethal in both vertebrates and invertebrates. In addition to playing a role in transcriptional regulation and RNA silencing, as a core member of the SMN (survival of
Cauchi, Ruben J.
core +3 more sources
Biology Open, 2017 Many ribonucleoproteins (RNPs), which are comprised of noncoding RNA and associated proteins, are involved in essential cellular processes such as translation and pre-mRNA splicing.
Aaron R. Poole +4 more
doaj +1 more source
Malaria infected red blood cells release small regulatory RNAs through extracellular vesicles [PDF]
, 2018 The parasite Plasmodium falciparum causes the most severe form of malaria. Cell communication between parasites is an important mechanism to control population density and differentiation.
Adapa, Swamy R. +9 more
core +2 more sources
Journal of Biological Chemistry, 2009 In this study, we sought to investigate the mechanism by which heterogeneous nuclear ribonucleoprotein (hnRNP) H and F regulate proteolipid protein (PLP)/DM20 alternative splicing.
E. Wang, F. Cambi
semanticscholar +1 more source
PHF5A promotes colorectal cancerprogression by alternative splicing of TEAD2
Molecular Therapy: Nucleic Acids, 2021 Dysregulated alternative splicing (AS) plays critical roles in driving cancer progression, and the underlying mechanisms remain largely unknown. Here, we demonstrated that PHF5A, a component of U2 small nuclear ribonucleoproteins, was frequently ...
Yue Chang +21 more
doaj