Results 71 to 80 of about 9,338 (256)
Salvage enzymes in nucleotide biosynthesis [PDF]
Balanced pools of deoxyribonucleoside triphosphates (dNTPs), the building blocks of DNA, and ribonucleoside triphosphates (NTPs), the precursors of RNA, are crucial for a controlled cell proliferation.
Kosinska, Urszula
core
Hachimoji DNA and RNA: A genetic system with eight building blocks [PDF]
Reported here are DNA and RNA-like systems built from eight (hachi-) nucleotide letters (-moji) that form four orthogonal pairs. This synthetic genetic biopolymer meets the structural requirements needed to support Darwinism, including a polyelectrolyte ...
Bates, Alison M.+15 more
core +1 more source
Adenosine 5'-phosphate was converted to the 2', 3'-cyclic phosphate by the treatment with dimethylformamide at reflux temperature. The reaction was shown to be proceeded by the initial release of the phosphoryl group as an"activated phosphoric acid"and rephosphorylated to furnish the 2', 3'-cyclic phosphate. In fact a ribonucleoside and phosphoric acid,
Ikuko Kawai, Tohru Ueda
openaire +3 more sources
Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy+7 more
wiley +1 more source
Synthesis of 5''-phosphate 2'-O-ribosylribonucleosides [Nr(p)] of four common ribonucleosides, and 3'-phosphoramidites of 5''-phosphate 2'-O-ribosyladenosine and 2'-O-ribosylguanosine using the H-phosphonate chemistry is described.
Marcin K. Chmielewski+1 more
doaj +1 more source
Alginate dialdehyde (ADA)‐gelatin (GEL) hydrogels are supplemented with mesoporous bioactive glass nanoparticles (MBGNs) and human platelet lysate (HPL) to enhance the biological performance of 3D printed scaffolds. Improved printability and higher shape fidelity are observed by incorporating 0.1% (w/v) MBGNs.
Yijun Zhao+2 more
wiley +1 more source
An Unusual Mode of DNA Duplex Association: Watson-Crick Interaction of All-Purine Deoxyribonucleic Acids [PDF]
SummaryNucleic acid duplexes associating through purine-purine base pairing have been constructed and characterized in a remarkable demonstration of nucleic acids with mixed sequence and a natural backbone in an alternative duplex structure.
Albalos, Maria+2 more
core +1 more source
Optical Probes for Cellular Imaging of G‐quadruplexes: Beyond Fluorescence Intensity Probes
DNA and RNA can fold into tetra‐stranded helical structures known as G‐quadruplexes (G4s). There is mounting evidence suggesting that these structures have important biological roles. In this minireview we discuss advances in the design of optical probes for the detection of G4s that offer intensity‐independent readouts that address limitations of ...
Jenna Robinson+3 more
wiley +2 more sources
Incorporation of Histamine Ribonucleoside into Soluble Proteins [PDF]
ISOTOPICALLY labelled histamine ribonucleoside can be detected in the urine of experimental animals after intraperitoneal administration of either 2(ring)−14C-labelled histamine1, or similarly labelled histamine-adenine-dinucleotides2. However, in such experiments the quantities of histamine ribonucleoside recovered from the urine represent only a ...
Frieda Ungar+2 more
openaire +3 more sources
ABSTRACT Deep sequencing of ribosome footprints, also known as ribosome profiling (Ribo‐seq), enables the quantification of mRNA translation and a comprehensive view of the translatome landscape. Here, we report an optimised Ribo‐seq protocol and analysis pipeline for the model green alga, Chlamydomonas reinhardtiii (Chlamydomonas).
Yen‐Ling Lin+4 more
wiley +1 more source