Results 71 to 80 of about 7,921 (135)

In vitro DNA/RNA Adductomics to Confirm DNA Damage Caused by Benzo[a]pyrene in the Hep G2 Cell Line

open access: yesFrontiers in Chemistry, 2019
In the development of new chemical substances, genetic toxicity evaluations are a high priority for safety risk management. Evaluation of the possibility of compound carcinogenicity with accuracy and at reasonable cost in the early stages of development ...
Toshihide Takeshita, Robert A. Kanaly
doaj   +1 more source

The search for an identification of amino acids, nucleobases and nucleosides in samples returned from Mars [PDF]

open access: yes
The Mars Sample Return mission will provide us with a unique source of material from our solar system; material which could advance our knowledge of the processes of chemical evolution. As has been pointed out, Mars geological investigations based on the
Gehrke, Charles W.   +4 more
core   +1 more source

Phosphate absorption by Arabidopsis thaliana : the effects of phosphorus nutritional status : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Plant Biology and Biotechnology at Massey University, Palmerston North, New Zealand [PDF]

open access: yes, 1997
The effect of phosphorus nutritional status on phosphate uptake within the concentration range of the high affinity uptake mechanism, and subsequent translocation to the shoot was investigated in the plant species Arabidopsis thaliana.
Clark, Gregory Thomas
core  

Stimuli-responsive releasing of gold nanoparticles and liposomes from aptamer-functionalized hydrogels [PDF]

open access: yes, 2011
This is an author-created, un-copyedited version of an article accepted for publication/published in Nanotechnology. IOP Publishing Ltd is not responsible for any errors or omissions in this version of the manuscript or any version derived from it.
Dave, Neeshma   +2 more
core   +1 more source

INTRACELLULAR Leishmania amazonensis KILLING INDUCED BY THE GUANINE NUCLEOSIDE 8-BROMOGUANOSINE

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1998
In this study we investigated the effect of 8-Bromoguanosine, an immunostimulatory compound, on the cytotoxicity of macrophages against Leishmania amazonensis in an in vitro system. The results showed that macrophages treated with 8-Bromoguanosine before
GIORGIO Selma, BARÃO Sandra C.
doaj  

Design, synthesis, conformational analysis and nucleic acid hybridisation properties of thymidyl pyrrolidine-amide oligonucleotide mimics (POM) [PDF]

open access: yes, 2003
Pyrrolidine-amide oligonucleotide mimics (POM) 1 were designed to be stereochemically and conformationally similar to natural nucleic acids, but with an oppositely charged, cationic backbone.
Cooper, M.A.   +5 more
core   +1 more source

Characterization of nucleoside transport in the intestinal protozoan parasite Giardia intestinalis. [PDF]

open access: yes, 1994
A rapid sampling technique has been adapted and used to measure nucleoside transport in a human-derived isolate of the intestinal protozoan parasite Giardia intestinalis (syn. G.
Davey, Robert Andrew
core  

Abiotic Ribonucleoside Formation in Aqueous Microdroplets: Mechanistic Exploration, Acidity, and Electric Field Effects

open access: yesChemistryEurope
Aqueous microdroplets have been reported to dramatically increase the rate of chemical reactions. Proposed mechanisms for this acceleration include confinement effects upon droplet evaporation, and Brønsted acid or electric field catalysis at the air ...
Maciej Piejko   +3 more
doaj   +1 more source

An Efficient and Short Route for the Synthesis of Reverse Pyrrole Ribonucleosides

open access: yesJournal of the Brazilian Chemical Society, 2002
The synthesis of reverse pyrrole ribonucleosides methyl 5-C-(4-acetyl-5-methyl-pyrrol-1-yl)-2,3-O-isopropylidene-5-deoxy- beta-D-ribofuranoside (10), methyl 5-C-(4-ethoxycarbonyl-5-methyl-pyrrol-1-yl)-2,3-O-isopropylidene-5-deoxy- beta-D-ribofuranoside ...
Pereira Letícia O. R.   +3 more
doaj  

Engineering a Bifunctional Fusion Purine/Pyrimidine Nucleoside Phosphorylase for the Production of Nucleoside Analogs

open access: yesBiomolecules
Nucleoside phosphorylases (NPs) are pivotal enzymes in the salvage pathway, catalyzing the reversible phosphorolysis of nucleosides to produce nucleobases and α-D-ribose 1-phosphate.
Daniel Hormigo   +4 more
doaj   +1 more source

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