Under iron‐limited conditions, FsrA base‐pairs with the intergenic region between epeX and epeE, enhancing epeE translation and triggering EPE production. Toxin‐mediated cell lysis releases nutrients, including iron, which can be taken up by surviving cells.
Sarah Miercke +3 more
wiley +1 more source
This review illustrates how intracellular bacterial pathogens—such as Brucella, Mycobacterium tuberculosis, and Legionella—secrete effector proteins that specifically target the IRE1α, PERK, and ATF6 branches of the unfolded protein response (UPR) to hijack ER stress signaling.
Enhui Dai +5 more
wiley +1 more source
Ay et al. investigated the cellular mechanisms behind the role of lysophosphatidic acid (LPA) in FGF23 production. They revealed that LPA cooperates with 1,25‐dihydroxyvitamin D (1,25D), that is, the bioactive form of vitamin D known to stimulate FGF23 synthesis. This synergy entails MAPK signaling and the induction of the gene encoding the interleukin‐
Birol Ay +7 more
wiley +1 more source
[Highly toxic type Ⅱ ribosome-inactivating proteins ricin and abrin and their detection methods: a review]. [PDF]
Liang L, Xia J, Liu C, Liu S.
europepmc +1 more source
Antiviral Activity of PD-L1 and PD-L4, Type 1 Ribosome Inactivating Proteins from Leaves of Phytolacca dioica L. in the Pathosystem Phaseolus vulgaris-Tobacco Necrosis Virus (TNV). [PDF]
Bulgari D +4 more
europepmc +1 more source
Functional Assays for Measuring the Catalytic Activity of Ribosome Inactivating Proteins. [PDF]
Zhou Y, Li XP, Kahn JN, Tumer NE.
europepmc +1 more source
Correction: Generality of toxins in defensive symbiosis: Ribosome-inactivating proteins and defense against parasitic wasps in Drosophila. [PDF]
Ballinger MJ, Perlman SJ.
europepmc +1 more source
Exploring two tumor treatment strategies: effectiveness of ribosome inactivating proteins and mesenchymal stem cells/MSC derived extracellular vesicles in cancer treatment. [PDF]
Mavaei M +7 more
europepmc +1 more source
Ribosome Inactivating Proteins: From Plant Defense to Treatments against Human Misuse or Diseases. [PDF]
Barbier J, Gillet D.
europepmc +1 more source

