Equal Neutralization Potency of Antibodies Raised against Abrin Subunits
Antibodies, 2020 Abrin and ricin are potent AB toxins, which are considered biological threats. To date, there are no approved treatments against abrin or ricin intoxications.
Yoav Gal +9 more
doaj +1 more source
TRAIL (CD253) Sensitizes Human Airway Epithelial Cells to Toxin-Induced Cell Death
mSphere, 2018 Inhalation of ricin toxin is associated with the onset of acute respiratory distress syndrome (ARDS), characterized by hemorrhage, inflammatory exudates, and tissue edema, as well as the nearly complete destruction of the lung epithelium.
Yinghui Rong +4 more
doaj +1 more source
Syntaxin 16 and syntaxin 5 are required for efficient retrograde transport of several exogenous and endogenous cargo proteins [PDF]
, 2007 Retrograde transport allows proteins and lipids to leave the endocytic pathway to reach other intracellular compartments, such as trans-Golgi network (TGN)/Golgi membranes, the endoplasmic reticulum and, in some instances, the cytosol. Here, we have used
Amessou, Mohamed +7 more
core +1 more source
A double safety lock tumor-specific device for suicide gene therapy in breast cancer [PDF]
, 2020 Producción CientíficaThe complexity and continuous evolution of cancer make the design of novel strategies of treatment a constant challenge in biomedicine.
Arias Vallejo, Francisco Javier +5 more
core +2 more sources
Extensive evolution of cereal ribosome-inactivating proteins translates into unique structural features, activation mechanisms, and physiological roles [PDF]
, 2017 Ribosome-inactivating proteins (RIPs) are a class of cytotoxic enzymes that can depurinate rRNAs thereby inhibiting protein translation. Although these proteins have also been detected in bacteria, fungi, and even some insects, they are especially ...
De Zaeytijd, Jeroen, Van Damme, Els
core +2 more sources
Immunochromatography Detection of Ricin in Environmental and Biological Samples
Nano Biomedicine and Engineering, 2011 Ricin has been considered as a potential agent of biological warfare or terrorist attack. This work is aimed to develop and evaluate a rapid test strip for the assay of ricin in environmental and biological samples.
Junhua Wu +7 more
doaj +1 more source
A Glycoprotein-Based Surface-Enhanced Raman Spectroscopy-Lateral Flow Assay Method for Abrin and Ricin Detection. [PDF]
Toxins (Basel)Xiao L +8 more
europepmc +3 more sources
Methods for nanoparticle labeling of ricin and effect on toxicity [PDF]
, 2009 The unique optical properties associated with nanostructured materials that support the excitation of surface plasmons offer many new opportunities for the enhanced optical investigation of biological materials that pose a security threat. In particular,
Graham, Duncan +4 more
core +1 more source
Toxins, 2018 Ricin, a highly lethal toxin derived from the seeds of Ricinus communis (castor beans) is considered a potential biological threat agent due to its high availability, ease of production, and to the lack of any approved medical countermeasure against ...
Reut Falach +11 more
doaj +1 more source
The role of CDC48 in the retro-translocation of non-ubiquitinated toxin substrates in plant cells [PDF]
, 2009 When the catalytic A subunits of the castor bean toxins ricin and Ricinus communis agglutinin (denoted as RTA and RCA A, respectively) are delivered into the endoplasmic reticulum (ER) of tobacco protoplasts, they become substrates for ER ...
Aldo Ceriotti +69 more
core +2 more sources