Results 31 to 40 of about 10,421 (212)

Novel small molecule retrograde transport blocker confers post-exposure protection against ricin intoxication

open access: yesActa Pharmaceutica Sinica B, 2020
Ricin is a highly toxic type 2 ribosome-inactivating protein (RIP) which is extracted from the seeds of castor beans. Ricin is considered a potential bioterror agent and no effective antidote for ricin exists so far.
Xu Zhao   +7 more
doaj  

TRAIL (CD253) Sensitizes Human Airway Epithelial Cells to Toxin-Induced Cell Death

open access: yesmSphere, 2018
Inhalation of ricin toxin is associated with the onset of acute respiratory distress syndrome (ARDS), characterized by hemorrhage, inflammatory exudates, and tissue edema, as well as the nearly complete destruction of the lung epithelium.
Yinghui Rong   +4 more
doaj   +1 more source

Detection of Ricin Contamination in Ground Beef by Electrochemiluminescence Immunosorbent Assay

open access: yesToxins, 2011
Ricin is a highly toxic protein present in the seeds of Ricinus communis (castor), grown principally as a source of high quality industrial lubricant and as an ornamental.
David L. Brandon
doaj   +1 more source

Ricin and abrin

open access: yesMedicine, 2007
Ricin is a type 2 ribosome-inactivating protein derived from the beans of the castor oil plant, Ricinus communis. It exerts toxicity by inhibiting protein synthesis. Many of the features seen in poisoning can be explained by ricin-induced endothelial cell damage, which leads to fluid and protein leakage and tissue oedema, causing so-called ‘vascular ...
openaire   +2 more sources

Development of a bioassay to quantify the ricin toxin content of castor bean (Ricinus communis L.) seeds - doi: 10.4025/actasciagron.v34i4.11284

open access: yesActa Scientiarum: Agronomy, 2011
In this study, we developed a bioassay to quantify the ricin toxin content of castor bean seeds. Existing quantification methods do not always reflect actual toxicity of the seeds analyzed, which may present lower ricin content even though they are more ...
Carlos Alberto Rauer Demant   +2 more
doaj   +1 more source

Chemical Components of the Dried Latex of Euphorbia resinifera Berg and Its Medicinal Features

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT A great deal of research has been carried out on the latex of Euphorbia resinifera Berg, which is an important source of several compounds of therapeutic and medicinal interest. Extraction, synthesis, and hemi synthesis pathways continue to reveal the existence of other new products with anticancer, antioxidant, antidiuretic, and antimalarial ...
Doaa Hammad   +5 more
wiley   +1 more source

Oligo‐Adenine Derived Secondary Nucleic Acid Frameworks: From Structural Characteristics to Applications

open access: yesAngewandte Chemie, Volume 136, Issue 45, November 4, 2024.
Supramolecular oligo‐adenine structures, including A‐motif, T ⋅ A‐T triplex, adenine‐cyanuric acid triplex, and adenine‐coralyne‐adenine complex, find growing interest in the area of DNA‐nanotechnology, and significant recent advances and applications of these frameworks are demonstrated.
Yuwei Hu, Itamar Willner
wiley   +2 more sources

A Critical Overview of Common Foodborne Toxicants and Methods for Their Reliable Detection

open access: yesFood Frontiers, EarlyView.
ABSTRACT Food is an essential commodity for human health. However, toxicants such as mycotoxins, heavy metals, acrylamide, and pesticides can be present in food either naturally or through processing, packaging, or some anthropogenic activities. A thorough review of carefully selected studies revealed that climate change and pandemics have led to an ...
Betty Bowe Acquah   +1 more
wiley   +1 more source

Über Ricin‐stearolsäure [PDF]

open access: yesBerichte der deutschen chemischen Gesellschaft, 1913
n ...
openaire   +3 more sources

Optimization of Lipid Nanoparticles with Robust Efficiency for the Delivery of Protein Therapeutics to Augment Cancer Immunotherapy

open access: yesAdvanced Science, Volume 12, Issue 17, May 8, 2025.
This study develops lipid nanoparticles (LNPs) combining cationic and ionizable lipids for efficient cytosolic protein delivery. Optimized LNPs deliver functional proteins, including antibodies, enzymes, and Cas9, with high serum stability and albumin‐mediated endocytosis.
Lanfang Ren   +6 more
wiley   +1 more source

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