Results 121 to 130 of about 121,575 (281)

Bedaquiline Resistance and Molecular Characterization of Rifampicin-Resistant Mycobacterium Tuberculosis Isolates in Zhejiang, China

, 2023
Enyu Tong,1,* Ying Zhou,1,* Zhengwei Liu,2 Yelei Zhu,2 Mingwu Zhang,2 Kunyang Wu,2 Junhang Pan,2 Jianmin Jiang1– 3 1School of Public Health, Hangzhou Normal University, Hangzhou, 311100, People’s Republic of China; 2Tuberculosis Control ...
Wu K, Jiang J, Liu Z, Pan J, Zhu Y, Zhang M, Zhou Y, Tong E   +7 more
core  

Therapeutic Inertia in Hidradenitis Suppurativa: Could Defensive Medicine Play a Role?

JEADV Clinical Practice, EarlyView.
Anju George, Alejandro Molina‐Leyva
wiley   +1 more source

Proteomic analysis in hidradenitis suppurativa reveals systemic inflammation in all disease stages

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Proteomic profiling reveals systemic inflammation in patients with hidradenitis suppurativa, even in early disease. Distinct mediators (e.g. TGF‐α, OSM, HGF) are elevated early, whereas others correlate with clinical severity (e.g. IL‐6, VEGF‐A, IL‐17A) or disease duration (e.g.
Lotta Sandelin Francke, Ansam Al‐Bayatti, Hanqian Zhang, Mohammad Alimohammadi, Hans Törmä, Enikö Sonkoly   +5 more
wiley   +1 more source

Pathogenesis of hidradenitis suppurativa: From susceptibility to chronicity

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This review describes hidradenitis suppurativa as a heterogeneous disorder in which genetic susceptibility, epithelial dysfunction, environmental exposures, immune activation and microbial ecology converge differently across patients and disease stages.
Kelsey R. van Straalen, Nisha S. Chandran, Jean M. Fletcher, Evangelos J. Giamarellos‐Bourboulis, Elia Rosi, Gregor B. E. Jemec   +5 more
wiley   +1 more source

Corynebacterium striatum‐Associated Pyogenic Osteomyelitis With Direct Extension From Postoperative Empyema

Respirology Case Reports
Corynebacterium striatum can cause postoperative empyema. C. striatum‐associated empyema may be associated with osteomyelitis. Rifampicin is a viable therapeutic option for C. striatum infection.
Shinnosuke Fukushima, Kazuhiro Noma, Hideharu Hagiya   +2 more
doaj   +1 more source

Development and Validation of a UPLC-MS/MS Method for Therapeutic Drug Monitoring, Pharmacokinetic and Stability Studies of First-Line Antituberculosis Drugs in Urine

Molecules
Tuberculosis (TB) remains one of the leading global causes of mortality. Several methods have been established to detect anti-TB agents in human plasma and serum. However, there is a notable absence of studies analyzing TB drugs in urine.
Mohamed Abouzid, Katarzyna Kosicka-Noworzyń, Marta Karaźniewicz-Łada, Prakruti Rao, Nisha Modi, Yingda L. Xie, Scott K. Heysell, Anna Główka, Leonid Kagan   +8 more
doaj   +1 more source

Next Generation Smart Implant Surfaces: Engineering Multifunctional Antimicrobial, Immunomodulatory and Regenerative Interfaces

Journal of Periodontal Research, EarlyView.
Natural‐inspired nano‐textured implant surfaces can be functionalised to modulate macrophage polarisation and local immune responses. This bioactive control promotes improved tissue integration and healing outcomes. ABSTRACT Dental implants rely on a stable and functional interface between the implant surface, surrounding tissues, and the oral ...
Roberto S. Pessoa, Lauren E. Steele, Mehvish Mumtaz, Denver P. Linklater, Neil M. O'Brien‐Simpson, Vladimir Baulin, Peter Kingshott, Roy Judge, Alastair J. Sloan, Elena P. Ivanova   +9 more
wiley   +1 more source

Differential ubiquitin modifications of ESCRT‐I subunits VPS37‐1 and VPS28‐2 positively regulate plant immunity

New Phytologist, EarlyView.
The RING type ubiquitin ligase (E3), XBAT35.2, positively regulates FLS2‐mediated plant immunity against bacterial pathogens by modifying the ESCRT‐I subunits VPS28‐2 and VPS37‐1 with distinct ubiquitin chain types. Summary Sensing of pathogen‐associated molecular patterns (PAMPs) by pattern recognition receptors at the cell surface initiates the first
Chaofeng Wang, Yi Zhang, Bangjun Zhou, Pooja Verma, Lirong Zeng   +4 more
wiley   +1 more source

Synergy and rifampicin [PDF]

Journal of Antimicrobial Chemotherapy, 1977
openaire   +2 more sources

Subversion of plant endomembrane trafficking by a Plasmodiophora brassicae effector PbALE that recruits membrane components at the host–pathogen interface to aid in colonization

New Phytologist, EarlyView.
Schematics of ΔSPPbALE‐induced disruption of plant endomembrane trafficking impairs both preinvasive and postinvasive immunity against filamentous fungi and facilitates intracellular colonization by Plasmodiophora brassicae. Summary Plasmodiophora brassicae, an intracellular biotrophic protist that causes clubroot in crucifers, extensively alters the ...
Musharaf Hossain, Jiangying Tu, Yangdou Wei, Peta C. Bonham‐Smith, Christopher D. Todd   +4 more
wiley   +1 more source