Results 101 to 110 of about 121,575 (281)

Mutations outside the rifampicin resistance-determining region associated with rifampicin resistance in Mycobacterium tuberculosis

, 2011
Objectives: Ninety-six percent of rifampicin resistance in Mycobacterium tuberculosis was shown to be associated with mutations inside the 81 bp rifampicin resistance-determining region (RRDR) located in the centre of the rpoB gene.
Yam, WC, Cheng, VCC, Siu, GKH, Lau, RWT, Tsui, SKW, Ying Zhang, Zhang, Y, Wing-Cheong Yam, Lau, TCK, Kwok-Yung Yuen, Vincent C. C. Cheng, Gilman Kit Hang Siu, Ho, PL, Yew, WW, Yuen, KY, Terrence C. K. Lau, Wing-Wai Yew, Ricky W. T. Lau, Pak-Leung Ho, Stephen K. W. Tsui   +19 more
core   +1 more source

Resolution of proximal tubular dysfunction after liver transplantation in ATP8B1 deficiency: A case report

JPGN Reports, EarlyView.
Abstract Progressive familial intrahepatic cholestasis type 1 (PFIC1), caused by ATP8B1 deficiency, is a multisystem disorder with extrahepatic manifestations; however, renal involvement has rarely been described. We report a child with genetically confirmed PFIC1 who underwent living donor liver transplantation (LT) for progressive liver disease ...
Angela Marino, Nathalie Godefroid, Catherine De Magnée, Xavier Stephenne   +3 more
wiley   +1 more source

Acquired rifampicin resistance in thrice-weekly antituberculosis therapy: impact of HIV and antiretroviral therapy [PDF]

, 2014
Risk factors for acquired rifampicin resistance (ARR) among tuberculosis patients on thrice-weekly antituberculosis therapy were baseline isoniazid resistance and HIV.
Ramesh Kumar, Santhanakrishnan, Sridhar, R., Padmapriyadarsini, Chandrasekaran, Menon, Pradeep Aravindan, Narendran, G., Venkatesan, P., Bhavani, Kannabiran Perumal, Chandrasekhar, Chockalingam, Vijay, K., Swaminathan, Soumya, Kumar, Satagopan, Gomathi, S. N., Chandrasekhar, C., Kumar, S., Ramesh Kumar, S., Sekar, L., Vijay, Krishnamoorthy, Menon, P. A., Narendran, Gopalan, Padmapriyadarsini, C., Swaminathan, S., Gomathi, Sivaramakrishnan Narayan, Sridhar, Rathinam, Venkatesan, Perumal, Sekar, Lakshmanan, Bhavani, K. P.   +25 more
core   +1 more source

Primary Antimicrobial Resistance Among Mycobacterium Tuberculosis Isolates from HIV Seropositive and HIV Seronegative Patients in Dar es Salaam Tanzania. [PDF]

, 2008
The United Republic of Tanzania is one of the 22 high M. tuberculosis burden countries. Data collected between 2002 and 2007 indicate that the global prevalence of drug-resistant M. tuberculosis including MDR vary greatly.
Saathoff, Elmar, Mugusi, F., Saathoff, E., Moshiro Candida, Bosch, R., Urassa, W., Urassa, Willy, Mugusi Ferdinand, Fawzi Wafaie, Villamor, E., Mugusi, Ferdinand, Moshiro, C., Fawzi, W., Bosch, Ronald, Saathoff Elmar, Bosch Ronald, Msamanga Gernard, Msamanga, Gernard, Moshiro, Candida, Villamor Eduardo, Villamor, Eduardo, Fawzi, Wafaie, Urassa Willy   +22 more
core   +1 more source

Therapeutic Challenges in Managing Coexisting Hidradenitis Suppurativa and Squamous Cell Carcinoma: A Clinical Case Study

JEADV Clinical Practice, EarlyView.
ABSTRACT Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder affecting intertriginous areas. Long‐standing HS can undergo malignant transformation into squamous cell carcinoma (SCC), particularly in the perineal and gluteal regions. We report a 54‐year‐old man with severe, treatment‐refractory HS complicated by an aggressive verrucous
Michael Zolotas, Tereza Jakovljevicova, Kamran Ghoreschi, Kerstin Kusch, Marisa Klemp, Robert Sabat, Georgios Kokolakis   +6 more
wiley   +1 more source

Comparison of Nucleotide MALDI-TOF MS with Xpert MTB/RIF for Rifampicin Susceptibility Identification and Associated Risk Factors of Rifampicin Resistance Among Drug Resistant Mycobacterium tuberculosis [PDF]

Song Song,1,* Honghong Xu,1,* Jiawei Cao,2,* Guanghong Wu,2 Haiyan Sun,1 Xiaoqi Dai,1 Xuekui Li,1 Meng Chen,1 Menghan Zhang,1 Yueming Yan,1 Jingfeng Tong,3 Zhongdong Wang1 1Institute of Tuberculosis Control, Qingdao Preventive Medicine ...
Li X, Cao J, Chen M, Tong J, Song S, Zhang M, Xu H, Wu G, Sun H, Yan Y, Wang Z, Dai X   +11 more
core  

Rifampicin-Loaded Polyelectrolyte Complex Eliminates Intracellular Bacteria through Thiol-Mediated Cellular Uptake and Oxidative Stress Enhancement

The poor accumulation of antibiotics in the cytoplasm leads to the poor eradication of intracellular bacteria. Herein, a polyelectrolyte complex (PECs@Rif) allowing direct cytosolic delivery of rifampicin (Rif) was developed for the treatment of ...
Ge Gao (5909), Zhaoxin Xia (14758189), Yulong Liao (1585696), Shiyong Zhang (1921348)   +3 more
core   +1 more source

Pharmacokinetic interactions between rifampicin and efavirenz in HIV-TB coinfections [PDF]

Universa Medicina, 2009
The increased percentage of patients with HIV-TB coinfection leads to inevitable interactions between rifampicin and efavirenz. Efavirenz is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) for the treatment of HIV infection.
Yenny
doaj  

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Nonthermal plasma approaches for combating implant‐associated infections: A compendious review

VIEW, EarlyView.
Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe, Satish Rojekar, Amol Gholap, K. Navaneetha Pandiyaraj, Mukesh Patekar, Claudia Riccardi, R. R. Deshmukh, Tomáš Kovářík, Kalim Deshmukh   +8 more
wiley   +1 more source