Results 81 to 90 of about 121,575 (281)

Detection of multidrug resistant Mycobacterium tuberculosis in Tabuk, Saudi Arabia, using Genotype MTBDRplus

open access: yesInternational Journal of Mycobacteriology, 2019
Background: The global increase in the rates of multidrug-resistant (MDR) tuberculosis (TB) has made the timely identification of resistant Mycobacterium tuberculosis complex strains an important emergence to achieve effective disease management and to ...
Eltayib Hassan Ahmed-Abakur   +1 more
doaj   +1 more source

Rifampicin curing of plasmids in Escherichia coli K12−rifampicin resistant host

open access: yes, 1984
The in-vitro rifampicin curing of R-plasmids JR225, BN102, BN106 and F’-plasmid F’lac+/R386 in Escherichia coli K12 rifampicin-resistant host J62–2 is described. The minimum rifampicin curing concentration and the frequency of curing of plasmids from the
E E Obaseiki-Ebor
core   +1 more source

Challenges for interpreting results of antimicrobial susceptibility testing for treating infections of foals with Rhodococcus equi

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Rhodococcus equi is a facultative intracellular pathogen and a major cause of pneumonia in foals worldwide. The standard treatment for affected foals is a combination of a macrolide with rifampicin. The widespread use of this combination has led to the emergence of multidrug‐resistant (MDR) strains of R. equi.
Marlane Geribone Seeger   +7 more
wiley   +1 more source

Multi-Fluorescence Real-Time PCR Assay for Detection of RIF & INH Resistance of M. tuberculosis

open access: yesFrontiers in Microbiology, 2016
Background: Failure to early detect multidrug-resistant tuberculosis (MDR-TB) results in treatment failure and poor clinical outcomes, and highlights the need to rapidly detect resistance to rifampicin (RIF) and isoniazid (INH)Methods: In Multi ...
Jingfu ePeng   +11 more
doaj   +1 more source

Predicting outcomes in equine peritonitis: Multivariable analysis of admission and post‐admission data from a UK hospital population

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Peritonitis is life‐threatening, and limited information exists regarding outcomes and predictors of survival. Objectives To report short‐ and long‐term outcomes in horses diagnosed with peritonitis and identify factors associated with survival. Study Design Retrospective observational. Methods Data were obtained for horses admitted
E. K. Kopec   +4 more
wiley   +1 more source

Impact of COVID-19 pandemic on tuberculosis [PDF]

open access: yesMedical Laboratory Journal
Background: Tuberculosis (TB) is a disease of the respiratory system that spreads when a patient coughs, sneezes, or spits. COVID-19, another respiratory disease, created havoc in 2020 and 2021.
Sae Pol   +5 more
doaj  

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

FORMULATION AND EVALUATION OFENTERIC COATED PELLETS OF RIFAMPICIN AND ISONIAZID WITH IMPROVED RIFAMPICIN STABILITY [PDF]

open access: yes, 2014
Objective: The aim of the present study is to formulate and evaluate enteric coated pellets of Rifampicin and Isoniazid with improved Rifampicin stability in invitro conditions.Methodology: Two different capsule formulations of these drugs were prepared.
Sreenivasa Reddy, M., Krishna T, Vamshi
core   +1 more source

Identification of single-point mutations in mycobacterial 16S rRNA sequences by confocal single-molecule fluorescence spectroscopy [PDF]

open access: yes, 2006
Marme N, Friedrich A, Müller M, et al. Identification of single-point mutations in mycobacterial 16S rRNA sequences by confocal single-molecule fluorescence spectroscopy. Nucleic Acids Research.
Friedrich, Achim   +7 more
core   +1 more source

Multi‐omics–driven precision medicine

open access: yesiMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li   +20 more
wiley   +1 more source

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