Results 71 to 80 of about 157,428 (296)

Adverse events in bedaquiline‐ and pretomanid‐based regimens for drug‐resistant tuberculosis from trial, implementation and pharmacovigilance studies

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract The availability of safety data, particularly concerning adverse events (AEs) associated with the new shorter regimen for drug‐resistant tuberculosis (TB) containing a bedaquiline–pretomanid‐based regimen, is still limited. This systematic review aims to provide a comprehensive and updated analysis of AEs related to this new regimen by ...
Nisa Maria   +4 more
wiley   +1 more source

Quantitative prediction of intravenous drug interactions caused by cytochromes P450 inhibitors and inducers

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Background Aims Pharmacokinetic interaction studies typically focus on oral administration, but intravenous (IV) administration bypasses intestinal degradation and hepatic first‐pass metabolism, leading to distinct drug–drug interaction (DDI) magnitude. This study aimed to develop a predictive model for DDIs involving IV‐administered drugs.
Vianney Tuloup   +2 more
wiley   +1 more source

Fabricating and Properties of Rifampicin-loaded Ethyl Cellulose Composites Via Electrospray

open access: yesStudia Universitatis Babes-Bolyai Chemia
Rifampin (Rif) is usually applied as first-line anti-tubercular drugs but has limited bioavailability. Herein, Rif-loaded ethyl cellulose (EC) composites was designed and fabricated by electrospray to improve therapy effectiveness and duration.
Xi LI   +9 more
doaj   +1 more source

Antileprotic medication induced psychosis in a patient of tuberous sclerosis: A case report

open access: yesIndian Journal of Community and Family Medicine, 2017
Tuberous sclerosis is a rare multisystem neurocutaneous genetic disorder primarily presented with seizures, mental retardation and hamartomas involving multiple systems.
Udit Kumar Panda   +2 more
doaj   +1 more source

Studies on Resistance to Vegetative (Vip3A) and Crystal (Cry1A) Insecticidal Toxins of Bacillus thuringiensis in Heliothis virescens (Fabricius) [PDF]

open access: yes, 2009
Bacillus thuringiensis (Bt) toxins expressed in commercial transgenic crop varieties are all δ-endotoxins (Cry toxins) but the identification of novel vegetative insecticidal proteins (Vip toxins) has extended the range of insecticidal proteins derived
Pickett, Brian R, Pickett, Brian R
core   +1 more source

Effect of oxycodone vs. morphine as first‐line opioid on new persistent opioid use after orthopaedic surgery: A prospective sequential cohort study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Background Postoperative opioids, intended for short‐term analgesia, contribute to new persistent opioid use in 1%–7% of patients, adversely affecting outcomes. Oxycodone may carry higher risk than morphine, though long‐term data are limited.
Eward J. Melis   +5 more
wiley   +1 more source

Efavirenz Plasma Concentrations and HIV Viral Load in HIV/AIDS-tuberculosis Infection Patients Treated with Rifampicin

open access: yesActa Medica Indonesiana, 2016
Aim:to determine the effect of a rifampicin-containing tuberculosis regimen on efavirenz plasma concentrations and viral load in HIV/AIDS-Tuberculosis infection patients who received efavirenz-based antiretroviral therapy.
Nina Mariana   +3 more
doaj  

A novel approach for lung delivery of rifampicin-loaded liposomes in dry powder form for the treatment of tuberculosis

open access: yesLung India, 2015
Background: Lung administration of antibiotics by nebulization is promising for improved treatment efficiency for pulmonary infections, as it increases drug concentration at sites of infection while minimizing systemic side effects.
Jagadevappa S Patil   +3 more
doaj   +1 more source

The susceptibility of pathogenic free-living amebae to chemotherapeutic agents : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Microbiology at Massey University [PDF]

open access: yes, 1979
The treatment of infections caused by pathogenic free-living amebae (PFLA) has, until only recently, been far from successful. The continued screening of chemotherapeutic agents against amebae of the genera Naegleria and Acanthamoeba is therefore of the ...
Donald, Jennifer Jane
core  

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