Phenotypic drug resistance and genome sequencing based identified mutations linked to resistance in Mycobacterium tuberculosis isolated from extrapulmonary clinical specimens. [PDF]
Mollalign H +14 more
europepmc +1 more source
Clinical Pharmacology Quality Assurance Program for Global HIV and Co‐Infection Drug Development
When the acquired immunodeficiency syndrome emerged in the 1980s, the United States National Institutes of Health established research networks to conduct clinical trials with the pharmaceutical industry to identify effective antiretroviral therapeutics.
Robin DiFrancesco +17 more
wiley +1 more source
THP-1-derived polarized macrophages differ by drug transporter transcriptomics, P-glycoprotein activity and rifampicin uptake kinetics. [PDF]
Hamburg K +5 more
europepmc +1 more source
Management of Tuberculosis: Manual for Health Workers [PDF]
Ministry of Health and Social Welfare, (MHSW)
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ABSTRACT Background and Aims Tuberculosis (TB) remains a major global health problem and poses significant challenges for diagnosis and treatment. The World Health Organization (WHO) recommends the use of molecular methods for the diagnosis and genotyping of Mycobacterium tuberculosis complex (MTBC).
Mohammad Yazdanmanesh +4 more
wiley +1 more source
High Levels of <i>Helicobacter pylori</i> Antimicrobial Resistance in Ireland-A Multicentre Study. [PDF]
Butler TJ +14 more
europepmc +1 more source
ABSTRACT Background and Aims Tuberculosis (TB) remains a major global health problem, and treatment progress is increasingly threatened by rising multidrug‐resistant tuberculosis (MDR‐TB). Delamanid (DLM), a nitroimidazole drug, has shown good efficacy and safety against both drug‐susceptible and drug‐resistant Mycobacterium tuberculosis (Mtb) strains.
Md. Mahmudul Islam +19 more
wiley +1 more source
Autophagy is essential for anti-<i>Wolbachia</i> drug efficacy in <i>Brugia malayi</i> and insect cells. [PDF]
Yousef A +7 more
europepmc +1 more source
ABSTRACT Introduction Intravesical Bacillus Calmette‐Guérin (BCG) therapy is an established treatment for non‐muscle‐invasive bladder cancer. Although systemic BCG infection is rare, infectious aortic aneurysm is a potentially fatal complication.
Daisuke Muto +9 more
wiley +1 more source
Involvement of African patient populations in clinical trials on leprosy: a scoping review. [PDF]
Haarmann M +6 more
europepmc +1 more source

