Results 191 to 200 of about 121,575 (281)

A Multi‐Scale Computational Framework for Anti‐Persister Tuberculosis Drug Discovery

Chemical Biology &Drug Design, Volume 108, Issue 4, October 2026.
This review presents an integrated QSAR–scaffold design–docking–MD framework for discovering anti‐persister tuberculosis agents active in dormant granuloma‐like conditions. By targeting Mtb bioenergetics and prioritising dual NDH‐2/cytochrome bd oxidase inhibition, the workflow advances rational design of candidates with higher resistance barriers ...
Said Moshawih, Anguraj Moulishankar, Chee Yan Choo, Khang Wen Goh, Chrismawan Ardianto, Azam Che Idris, Long Chiau Ming   +6 more
wiley   +1 more source

Tuberculosis Disease Severity Assessment Using Clinical Variables and Radiology Enabled by Artificial Intelligence. [PDF]

J Infect Dis
Ghanem M, Srivastava R, Ektefaie Y, Hoppes D, Rosenfeld G, Yaniv Z, Grinev A, Xu AY, Yang E, Velásquez GE, Harrison L, Rosenthal A, Savic RM, Jacobson KR, Farhat MR.   +14 more
europepmc   +1 more source

Diagnosis and Management of Infectious Encephalitis in Adults: Guidelines From the European Academy of Neurology and European Society of Clinical Microbiology and Infectious Diseases

European Journal of Neurology, Volume 33, Issue 10, October 2026.
ABSTRACT Background Encephalitis is difficult to diagnose and manage, posing a challenge to clinicians. Since the last European guidelines were published in 2010, novel causes have emerged, diagnostic processes have evolved and treatments assessed which need to be reflected in updated guidelines.
Julia Granerod, Johann Sellner, Jean‐Paul Stahl, Sylviane Defres, Alexandra Mailles, Erich Schmutzhard, Elisabeth Aurelius, Thomas Whitfield, Luca Massacesi, Maarten J. Titulaer, Pille Taba, Benedict D. Michael, Tehmina Bharucha, Lance Turtle, Brendan Sargent, Arina Tamborska, Jonathan Cattrall, Yun Huang, Eva Maria Hodel, Suzannah Lant, Glynn Webb, Rajish S. K. Shil, Shalley Dhar, Diederik van de Beek, Marie Studahl, Matthijs C. Brouwer, Uta Meyding‐Lamade, Ava Easton, Bhagteshwar Singh, Tom Solomon   +29 more
wiley   +1 more source

Electrospun PLA/PCL Membranes for Sustained Transdermal Rifampicin Delivery: Biocompatibility, Stability, and Antimycobacterial Activity. [PDF]

Polymers (Basel)
Juárez E, Ortiz E, Gama NO, Ruiz A, Guzmán-Beltrán S, Arias W, Aguilar-Méndez MA, San Martin-Martínez E, Vieyra H.   +8 more
europepmc   +1 more source

Lysin Motif Effectors Facilitate the Endophytic Colonization of Wheat by Sclerotinia sclerotiorum via Modulating Plant Immunity

Molecular Plant Pathology, Volume 27, Issue 10, October 2026.
Two LysM effectors of Sclerotinia sclerotiorum are essential for the endophytic colonization of wheat. SsLysM6/7 inhibit chitin‐induced immune responses and undermine wheat immunity to promote fungal growth. ABSTRACT Sclerotinia sclerotiorum is a necrotrophic fungus that causes severe plant diseases but can also colonize wheat as a symptomless ...
Yamin Du, Haohao Ren, Hui Tang, Yafei Chen, Jianqi Wang, Xiaofan Liu, Jiatao Xie, Jiasen Cheng, Yanping Fu, Daohong Jiang, Bo Li, Xiao Yu   +11 more
wiley   +1 more source

A liquid handling platform for standardized quantification of cell-free enzymatic activity encoded by antimicrobial resistance genes. [PDF]

Synth Biol (Oxf)
Bergum M, Suthakaran S, Martin B, Sutton JM, Moore SJ.   +4 more
europepmc   +1 more source

The combination of morphogenic regulators BABY BOOM and GRF‐GIF improves maize transformation efficiency and promotes leaf regeneration

New Phytologist, Volume 252, Issue 1, Page 260-275, October 2026.
Maize regeneration via somatic embryogenesis by ectopic expression of morphogenic factors TaGRF4‐TaGIF1 and ZmBBM. Summary Transformation is an indispensable tool for plant genetics and functional genomics. Although stable transformation in maize is no longer a major obstacle, there remains a need for accessible and efficient methods for academic ...
Zongliang Chen, Jiaqi Zhou, Mary Galli, Sessen Daniel Iohannes, Theresa Clark, Juan M. Debernardi, Jorge Dubcovsky, David Jackson, Andrea Gallavotti   +8 more
wiley   +1 more source

N-acetylcysteine as an adjunct to antibiotics against bacterial biofilms: A systematic review of in vitro evidence. [PDF]

Biofilm
Seksenbayev B, Suleimenov Y, Bekbayev A, Sadykov N, Omari A.   +4 more
europepmc   +1 more source

Multi‐Omics Analyses Reveal the Red and Far‐Red Light Combination Enhancing Heterologous Protein and Metabolite Production in Nicotiana benthamiana

Plant, Cell &Environment, Volume 49, Issue 10, Page 7435-7448, October 2026.
ABSTRACT Transient expression of exogenous protein in Nicotiana benthamiana leaves via agroinfiltration offers a rapid and efficient platform for functional gene discovery and heterologous production of valuable eukaryotic proteins and metabolites. Though light quality is an important factor for plant photomorphogenesis, its impact on the efficiency of
Yating Zhang, Fengjiao Wang, Ran Du, Tao Li, Shaoqun Zhou, Jianbin Yan, Wei Li   +6 more
wiley   +1 more source

Burden of Rifampicin Resistance Among Patients With Tuberculosis at a Tertiary Care Center in Uttarakhand, India: A Prospective Cross-Sectional Study. [PDF]

Cureus
Negi S, Singh M, Chandola I, Rawat J.
europepmc   +1 more source