Identification, Genotyping and Antimicrobial Susceptibility Testing of Brucella spp. Isolated from Livestock in Egypt [PDF]
Brucellosis is a highly contagious zoonosis worldwide with economic and public health impacts. The aim of the present study was to identify Brucella (B.) spp. isolated from animal populations located in different districts of Egypt and to determine their
El-Adawy, Hosny +9 more
core +1 more source
Anti-tubercular therapy (ATT) drugs are the mainstay of management of tuberculosis worldwide. These medicines are used extensively across the globe in treating tubercular infections of any organ.
Simarjit S Rehsi +6 more
doaj +1 more source
Synthesis, in vitro and in vivo evaluation of 3β-[18F]fluorocholic acid for the detection of drug-induced cholestasis in mice [PDF]
Introduction : Drug-induced cholestasis is a liver disorder that might be caused by interference of drugs with the hepatobiliary bile acid transporters. It is important to identify this interference early on in drug development.
De Lombaerde, Stef +7 more
core +3 more sources
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Rationing tests for drug-resistant tuberculosis - who are we prepared to miss? [PDF]
BACKGROUND: Early identification of patients with drug-resistant tuberculosis (DR-TB) increases the likelihood of treatment success and interrupts transmission.
A Faustini +35 more
core +4 more sources
Paraspinal Abscess Secondary to Tuberculous Spondylitis Diagnosed by Xpert MTB/RIF Assay in Rural Tanzania. [PDF]
A 31-year-old HIV-negative man presented to our clinic with a 6-month history of back pain and a swelling at the back. Radiological studies revealed lumbar vertebral destruction.
Hella, Jerry Joseph +3 more
core +1 more source
Rifampicin resistance is a major therapeutic challenge, particularly in tuberculosis, leprosy, P. aeruginosa and S. aureus infections, where it develops via missense mutations in gene rpoB.
Stephanie Portelli +5 more
semanticscholar +1 more source
The actinobacterial transcription factor RbpA binds to the principal sigma subunit of RNA polymerase [PDF]
RbpA is a small non-DNA-binding transcription factor that associates with RNA polymerase holoenzyme and stimulates transcription in actinobacteria, including Streptomyces coelicolor and Mycobacterium tuberculosis.
Aline Tabib-Salazar +82 more
core +1 more source
The objective of the study: to investigate the effectiveness of real-time PCR for express drug susceptibility testing in drug resistant pulmonary tuberculosis patients using sputum samples and specimens of lung tissue collected during surgery.Subjects ...
Yu. S. Alyapkina +3 more
doaj +1 more source
Early Detection of Multi-drug Resistant Tuberculosis and Mutations in Mycobacterium tuberculosis isolates using Line Probe Assay from a Tertiary Care Centre in Northern India [PDF]
Introduction: Early detection and drug susceptibility analysis of Mycobacterium tuberculosis (MTB) in the shortest possible time has been the driving force for research that aims to bridge the gap between detection and treatment.
Omar Rashid +6 more
doaj +1 more source

