Results 41 to 50 of about 191,709 (318)

Identification, Genotyping and Antimicrobial Susceptibility Testing of Brucella spp. Isolated from Livestock in Egypt [PDF]

open access: yes, 2019
Brucellosis is a highly contagious zoonosis worldwide with economic and public health impacts. The aim of the present study was to identify Brucella (B.) spp. isolated from animal populations located in different districts of Egypt and to determine their
El-Adawy, Hosny   +9 more
core   +1 more source

A rare case of tuberculosis spine on antitubercular drug succumbing to pseudomembranous enterocolitis

open access: yesJournal of Dr. NTR University of Health Sciences, 2021
Anti-tubercular therapy (ATT) drugs are the mainstay of management of tuberculosis worldwide. These medicines are used extensively across the globe in treating tubercular infections of any organ.
Simarjit S Rehsi   +6 more
doaj   +1 more source

Synthesis, in vitro and in vivo evaluation of 3β-[18F]fluorocholic acid for the detection of drug-induced cholestasis in mice [PDF]

open access: yes, 2017
Introduction : Drug-induced cholestasis is a liver disorder that might be caused by interference of drugs with the hepatobiliary bile acid transporters. It is important to identify this interference early on in drug development.
De Lombaerde, Stef   +7 more
core   +3 more sources

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Rationing tests for drug-resistant tuberculosis - who are we prepared to miss? [PDF]

open access: yes, 2016
BACKGROUND: Early identification of patients with drug-resistant tuberculosis (DR-TB) increases the likelihood of treatment success and interrupts transmission.
A Faustini   +35 more
core   +4 more sources

Paraspinal Abscess Secondary to Tuberculous Spondylitis Diagnosed by Xpert MTB/RIF Assay in Rural Tanzania. [PDF]

open access: yes, 2013
A 31-year-old HIV-negative man presented to our clinic with a 6-month history of back pain and a swelling at the back. Radiological studies revealed lumbar vertebral destruction.
Hella, Jerry Joseph   +3 more
core   +1 more source

Prediction of rifampicin resistance beyond the RRDR using structure-based machine learning approaches

open access: yesScientific Reports, 2020
Rifampicin resistance is a major therapeutic challenge, particularly in tuberculosis, leprosy, P. aeruginosa and S. aureus infections, where it develops via missense mutations in gene rpoB.
Stephanie Portelli   +5 more
semanticscholar   +1 more source

The actinobacterial transcription factor RbpA binds to the principal sigma subunit of RNA polymerase [PDF]

open access: yes, 2013
RbpA is a small non-DNA-binding transcription factor that associates with RNA polymerase holoenzyme and stimulates transcription in actinobacteria, including Streptomyces coelicolor and Mycobacterium tuberculosis.
Aline Tabib-Salazar   +82 more
core   +1 more source

EFFECTIVENESS OF REAL-TIME PCR FOR EXPRESS FIRST LINE DRUG SUSCEPTIBILITY TESTING OF TUBERCULOUS MYCOBACTERIA USING SPUTUM SAMPLES AND SURGICAL SPECIMENS OF LUNG TISSUE

open access: yesТуберкулез и болезни лёгких, 2019
The objective of the study: to investigate the effectiveness of real-time PCR for express drug susceptibility testing in drug resistant pulmonary tuberculosis patients using sputum samples and specimens of lung tissue collected during surgery.Subjects ...
Yu. S. Alyapkina   +3 more
doaj   +1 more source

Early Detection of Multi-drug Resistant Tuberculosis and Mutations in Mycobacterium tuberculosis isolates using Line Probe Assay from a Tertiary Care Centre in Northern India [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2020
Introduction: Early detection and drug susceptibility analysis of Mycobacterium tuberculosis (MTB) in the shortest possible time has been the driving force for research that aims to bridge the gap between detection and treatment.
Omar Rashid   +6 more
doaj   +1 more source

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