Results 11 to 20 of about 818,628 (334)
Applied Sciences, 2022 The association of cathepsin proteases in neurobiology is increasingly recognized. Our previous studies indicated that cathepsin-K-deficient (Ctsk−/−) mice have learning and memory impairments.
Denise M. T. Yu +6 more
doaj +1 more source
A Unified Mechanism on the Formation of Acenes, Helicenes, and Phenacenes in the Gas Phase. [PDF]
, 2020 A unified low-temperature reaction mechanism on the formation of acenes, phenacenes, and helicenes-polycyclic aromatic hydrocarbons (PAHs) that are distinct via the linear, zigzag, and ortho-condensed arrangements of fused benzene rings-is revealed. This
Ablikim, Utuq +8 more
core +1 more source
Oxetanes: Recent Advances in Synthesis, Reactivity and Medicinal Chemistry [PDF]
, 2016 The 4-membered oxetane ring has been increasingly exploited for its behaviors, i.e. influence on physicochemical properties as a stable motif in medicinal chemistry, and propensity to undergo ring opening reactions as a synthetic intermediate.
Bull, JA +4 more
core +1 more source
Efficient ring perception for the Chemistry Development Kit [PDF]
Journal of Cheminformatics, 2014 The Chemistry Development Kit (CDK) is an open source Java library for manipulating and processing chemical information. A key aspect in handling chemical structures is the determination of the chemical rings. The rings of a structure are used areas including descriptors, stereochemistry, similarity, screening and atom typing. The CDK includes multiple
Christoph Steinbeck, John W. May
openaire +2 more sources
CHIMIA, 2010 Research projects of the Department of Chemistry, University of Basel are reviewed ranging from the synthesis of complex natural products to the development of metalorganic catalysts and organocatalysts
Karl Gademann +5 more
doaj +1 more source
Ringing the changes in chemistry [PDF]
Nature, 1985 Comprehensive Heterocyclic Chemistry: The Structure, Reactions, Synthesis and Uses of Heterocyclic Compounds. Chairmen of the editorial board Alan R. Katritzky and Charles W. Rees. Pergamon: 1984. Eight volumes. 1375, 2200.
openaire +2 more sources
Trace Amine-Associated Receptor 1 Trafficking to Cilia of Thyroid Epithelial Cells
Cells, 2021 Trace amine-associated receptor 1 (rodent Taar1/human TAAR1) is a G protein-coupled receptor that is mainly recognized for its functions in neuromodulation.
Maria Qatato +8 more
doaj +1 more source
Molecular line emission in NGC1068 imaged with ALMA: II. The chemistry of the dense molecular gas [PDF]
, 2014 We present a detailed analysis of ALMA Bands 7 and 9 data of CO, HCO+, HCN and CS, augmented with Plateau de Bure Interferometer (PdBI) data of the ~ 200 pc circumnuclear disk (CND) and the ~ 1.3 kpc starburst ring (SB ring) of NGC~1068, a nearby (D = 14
Aalto, S. +21 more
core +2 more sources
Strain Release Chemistry of Photogenerated Small‐Ring Intermediates [PDF]
Chemistry – A European Journal, 2021 AbstractPhotochemical processes, such as isomerizations and cycloadditions, have proven to be very useful in the construction of highly strained molecular frameworks. Photoinduced ring strain enables subsequent exergonic reactions which do not require the input of additional chemical energy and provides a variety of attractive synthetic options leading
Adriana Luque, Jan Paternoga, Till Opatz
openaire +4 more sources
The Cu(OTf)2 catalysed microwave assisted synthesis of a new scaffold, 7-aryl-7,8-dihydropyrido[4,3-c]pyridazin-5(6H)-one [PDF]
, 2014 The synthesis of novel 7-aryl-7,8-dihydropyrido[4,3-c]pyridazin-5(6H)-ones is described including a one-step Mannich-type reaction followed by intramolecular ring closure of ethyl 3-methylpyridazine-4- carboxylate and aldimines, catalysed by the Lewis ...
De Coen, Laurens +5 more
core +2 more sources