Results 31 to 40 of about 856,718 (308)
Jahn-Teller instability in C6H6+ and C6H6- revisited
, 2003 The benzene cation (C6H6+) has a doublet (e_{1g}) ground state in hexagonal ring (D_{6h}) geometry. Therefore a Jahn-Teller (JT) distortion will lower the energy.
H. Jahn +4 more
core +1 more source
Biosensors, 2021 Biofilms growing on electrodes are the heart piece of bioelectrochemical systems (BES). Moreover, the biofilm morphology is key for the efficient performance of BES and must be monitored and controlled for a stable operation.
Andreas Netsch +2 more
doaj +1 more source
Lithiation of 4-membered heterocycles as useful strategy for the preparation of new molecular scaffolds: addressing the regioselectivity in azetidines and thietanes [PDF]
, 2013 Four-membered heterocycles (4-MH) with one or two heteroatoms are of great importance in medicinal chemistry and synthetic organic chemistry. This kind of scaffolds show peculiar structural features, related to the ring “puckering”, and biological ...
Carroccia, Laura +7 more
core
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
FEBS Letters, EarlyView.This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source
Label‐Free Fluorescent Kinase and Phosphatase Enzyme Assays with Supramolecular Host‐Dye Pairs
ChemistryOpen, 2019 The combination of the macrocyclic hosts p‐sulfonatocalix[4]arene and cucurbit[7]uril with the fluorescent dyes lucigenin and berberine affords two label‐free enzyme assays for the detection of kinase and phosphatase activity by fluorescence monitoring ...
Yan‐Cen Liu +4 more
doaj +1 more source
DNA Damaging Agents in Chemical Biology and Cancer
CHIMIA, 2020 Despite their toxicity, DNA alkylating drugs remain a cornerstone of anticancer therapy. The classical thinking was that rapidly dividing tumour cells left more of its DNA in an exposed single-stranded state, making these rapidly dividing cells more ...
Basilius Sauter, Dennis Gillingham
doaj +1 more source
A sensitive and selective chemiluminogenic probe for palladium [PDF]
, 2015 Palladium triggered removal of a propargyl group leads to the cleavage of the 1,2-dioxetane ring, leading to bright chemiluminescence. The reaction of the probe is highly specific for the Pd species, thus the probe described here has considerable ...
Akkaya, E.U. +3 more
core +1 more source
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Recent Biomimetic and Organocatalytic Syntheses of ?-Tocopherol
CHIMIA, 2010 We report here on our efforts to develop new strategies for the synthesis of ?-tocopherol, the biologically most significant member of the vitamin E family.
Antoinette Chougnet +2 more
doaj +1 more source
Molecular gas chemistry in AGN. II. High-resolution imaging of SiO emission in NGC1068: shocks or XDR? [PDF]
, 2010 This paper is part of a multi-species survey of line emission from the molecular gas in the circum-nuclear disk (CND) of the Seyfert 2 galaxy NGC1068. Single-dish observations have provided evidence that the abundance of silicon monoxide(SiO) in the CND ...
A. Fuente +87 more
core +3 more sources