Results 201 to 207 of about 17,697 (207)
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Hypoxia-stabilized RIPK1 promotes cell death
Nature Cell Biology, 2023Wei Ruan +2 more
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Monitoring RIPK1 Phosphorylation in the TNFR1 Signaling Complex
2018Receptor-interacting protein kinase 1 (RIPK1) is a component of the TNFR1 signaling complex (also known as complex I or TNFR-SC), where its ubiquitylation by cIAP1/2 and LUBAC serves to initiate prosurvival and proinflammatory responses through activation of the MAPK and NF-κB pathways. IKKα/β-mediated phosphorylation of RIPK1 in complex I was shown to
Dario, Priem +2 more
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Sanofi buys into Denali’s RIPK1 drugs
C&EN Global Enterprise, 2018In another sizable deal for Denali Therapeutics, Sanofi is paying $125 million to buy into a series of neuroinflammation compounds called RIPK1 inhibitors. The pact provides key funding for the molecules, which have potential activity across several diseases with large patient populations, including Alzheimer’s, multiple sclerosis, and arthritis.
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RIPK1, a key survival factor for hepatocytes
Journal of Hepatology, 2017Bleriot, Camille, Lecuit, Marc
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RIPK1 and necroptosis role in premature ageing
Nature Cell BiologyPanxue Wang, John Silke
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